首发抑郁症患者性生活质量影响因素研究
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摘要
目的探讨影响首发抑郁症患者性生活质量的因素。方法采用躯体化症状自评量表(SSS)、蒙哥马利抑郁评定量表(MADRS)、匹兹堡睡眠质量指数(PSQI)、亚利桑那性体验量表(ASEX)对118例首发未治疗的抑郁症患者(研究组)及年龄、性别、受教育程度匹配的106例健康对照者(对照组)进行评估。结果研究组的ASEX总分及各因子分均明显高于对照组(P <0. 05);研究组SSS总分及各因子分、MADRS总分、PSQI总分与ASEX总分及各因子分呈正相关性(P <0. 001)。回归分析显示躯体化症状各因子(除视物模糊外)、抑郁程度、睡眠质量对ASEX总分具有较好的预测作用。结论首发抑郁症患者抑郁程度、躯体化症状、睡眠质量与性生活质量存在相关性,患者的抑郁程度、躯体化症状影响性生活质量。
Objective To explore the factors influencing sexual life quality of patients with first-episode depression. Methods The somatic self-rating scale( SSS), Montgomery and Asberg Depression Rating Scale(MADRS),Pittsburgh Sleep Quality Index(PSQI) and Arizona Sexual Experience Scale(ASEX) were used in this paper. The study compared and evaluated 118 first untreated depressive patients( Study Group) and 106 healthy controls matched( Control Group) by age,sex and education. Results The total score and factor scores of ASEX in the study group were significantly higher than those in the control group( P < 0. 05),and the total score of SSS and the total score of MADRS,the total score of MADRS and the total PSQI score of the study group were positively correlated with the total score of ASEX and each factor( P < 0. 001). Regression analysis showed that all factors of somatization symptom( except for blurred vision),depressive symptoms and sleep quality had a good predictive effect on ASEX score. Conclusion There is a correlation between depression,somatization,sleep quality and the quality of sexual life in the first-episode depressions. Depression and somatization symptoms affect the quality of sexual life.
Objective To explore the factors influencing sexual life quality of patients with first-episode depression. Methods The somatic self-rating scale( SSS), Montgomery and Asberg Depression Rating Scale(MADRS),Pittsburgh Sleep Quality Index(PSQI) and Arizona Sexual Experience Scale(ASEX) were used in this paper. The study compared and evaluated 118 first untreated depressive patients( Study Group) and 106 healthy controls matched( Control Group) by age,sex and education. Results The total score and factor scores of ASEX in the study group were significantly higher than those in the control group( P < 0. 05),and the total score of SSS and the total score of MADRS,the total score of MADRS and the total PSQI score of the study group were positively correlated with the total score of ASEX and each factor( P < 0. 001). Regression analysis showed that all factors of somatization symptom( except for blurred vision),depressive symptoms and sleep quality had a good predictive effect on ASEX score. Conclusion There is a correlation between depression,somatization,sleep quality and the quality of sexual life in the first-episode depressions. Depression and somatization symptoms affect the quality of sexual life.
引文
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[6] Beck J G. Hypoactive sexual desire disorder:an overview[J].Consult Clin Psychology,1995,63(6):919-27.
[7] Charandabi S M,Rezaei N,Hakimi S,et al,Sleep disturbances and sexual function among men aged 45-75 years in an urban area of Iran[J]. Sleep Sci,2016,9(1):29-34.
[8]徐阿红.抑郁症躯体化与心理社会因素的相关研究[D].苏州:苏州大学,2010.
[9]姚德鸿.人类性功能的神经调控机制[J].现代中西医结合杂志,2003,12(18):1921-2,1939.
[10] Sumaya I C,Bailey D,Catlett S L. Differential effects of a shortterm high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist,ondansetron,the 5-HT3 receptor agonist,2-methyl-5-HT,and the SSRI,fluoxetine[J].Pharmacol Biochem Behav,2016,144:78-84.
[11] Wu Y Y,Jiang Y L,He X F,et al. 5-HT in the dorsal raphe nucleus is involved in the effects of 100-Hz electro-acupuncture on the pain-depression dyad in rats[J]. Exp Ther Med,2017,14(1):107-14.
[12]王平,司天梅.抑郁障碍、抗抑郁药和性功能障碍的关系研究进展[J].中国新药杂志,2010,22(19):2045-9.
[2] Clayton A H,Montejo A L. Major depressive disorder,antideprssants,and sexual dysfunction[J]. J Clin Psychiatry,2006,67 Suppl 6:33-7.
[3] De Berardis G,Pellegrini F,Franciosi M,et al. Clinical and psychological predictors of incidence of self reported erectile dysfunction in patients with type 2 diabetes[J]. J Urol,2007,177(1):252-7.
[4]邹庆波,潘长景.男性抑郁症患者性功能状况调查分析[J].中国性科学,2014,23(9):25-7.
[5]杨俊,刘继红.睡眠相关性阴茎勃起的研究进展[J].中国男科学杂志,2006,20(10):62-4.
[6] Beck J G. Hypoactive sexual desire disorder:an overview[J].Consult Clin Psychology,1995,63(6):919-27.
[7] Charandabi S M,Rezaei N,Hakimi S,et al,Sleep disturbances and sexual function among men aged 45-75 years in an urban area of Iran[J]. Sleep Sci,2016,9(1):29-34.
[8]徐阿红.抑郁症躯体化与心理社会因素的相关研究[D].苏州:苏州大学,2010.
[9]姚德鸿.人类性功能的神经调控机制[J].现代中西医结合杂志,2003,12(18):1921-2,1939.
[10] Sumaya I C,Bailey D,Catlett S L. Differential effects of a shortterm high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist,ondansetron,the 5-HT3 receptor agonist,2-methyl-5-HT,and the SSRI,fluoxetine[J].Pharmacol Biochem Behav,2016,144:78-84.
[11] Wu Y Y,Jiang Y L,He X F,et al. 5-HT in the dorsal raphe nucleus is involved in the effects of 100-Hz electro-acupuncture on the pain-depression dyad in rats[J]. Exp Ther Med,2017,14(1):107-14.
[12]王平,司天梅.抑郁障碍、抗抑郁药和性功能障碍的关系研究进展[J].中国新药杂志,2010,22(19):2045-9.