妊娠期糖尿病患者平均血小板体积(MPV)和血小板平均分布宽度(PDW)与妊娠结局相关
|
摘要
目的:探究平均血小板体积(MPV)和血小板平均分布宽度(PDW)在妊娠期糖尿病患者的变化及对妊娠结局的影响。方法:150例妊娠期就诊患者分为妊娠期糖尿病组(52例)、妊娠糖耐量受损组(50例)、妊娠糖耐量正常组(48例),检测MPV和PDW。分析MPV、PDW与妊娠结局的相关性。结果:妊娠期糖尿病组患者的MPV、PDW高于其他两组,差异有统计学意义(P<0.05)。妊娠期糖尿病组Apgar 5 min评分低、低体重儿率、早产儿率等不良妊娠结局比其他两组差,差异有统计学意义(P<0.05)。MPV、PDW与不良新生儿围生期结局呈正相关。结论:MPV、PDW等血小板参数影响妊娠结局。
Objective: To explore the changes of mean platelet volume(MPV)and mean platelet distribution width(PDW)in gestational diabetes mellitus(GDM)patients and their effects on pregnancy outcomes. Methods: 150 patients were divided into gestational diabetes mellitus group(52 cases), impaired gestational glucose tolerance group(50 cases), normal gestational glucose tolerance group(48 cases), MPV and PDW were detected. The correlation between MPV, PDW and pregnancy outcome was analyzed. Results: There were significantly high in MVP and PDW between gestational diabetes mellitus group and other two groups(P<0.05). Apgar 5-minute score, low birth weight rate and premature birth rate in gestational diabetes mellitus group were worse than those in other two groups(P<0.05). MPV and PDW were positively correlated with perinatal outcomes. Conclusion: MPV, PDW and other platelet parameters affect pregnancy outcomes.
Objective: To explore the changes of mean platelet volume(MPV)and mean platelet distribution width(PDW)in gestational diabetes mellitus(GDM)patients and their effects on pregnancy outcomes. Methods: 150 patients were divided into gestational diabetes mellitus group(52 cases), impaired gestational glucose tolerance group(50 cases), normal gestational glucose tolerance group(48 cases), MPV and PDW were detected. The correlation between MPV, PDW and pregnancy outcome was analyzed. Results: There were significantly high in MVP and PDW between gestational diabetes mellitus group and other two groups(P<0.05). Apgar 5-minute score, low birth weight rate and premature birth rate in gestational diabetes mellitus group were worse than those in other two groups(P<0.05). MPV and PDW were positively correlated with perinatal outcomes. Conclusion: MPV, PDW and other platelet parameters affect pregnancy outcomes.
引文
[1] 荣太梓.妊娠期糖尿病发病的危险因素及干预措施[J].蚌埠医学院学报,2017,42(11):203-204.
[2] STEIROPOULOS P,PAPANAS N,NENA E,et al.Mean platelet volume and platelet distribution width in patients with chronic obstructive pulmonary disease the role of comorbidities[J].Angiology,2013,64(7):535-539.
[3] 张丽杰.妊娠期高血压孕妇凝血功能及血小板参数变化与妊娠结局的关系[J].血栓与止血学,2015,12(5):320-321.
[4] SAHIN M S,KIZILIRMAK D.Changes at mean platelet volume and platelet distribution width levels after septoplasty and its correlation with Epworth sleepness scale[J].Journal of Craniofacial Surgery,2017,28(1):71-71.
[5] 卞桂萍,薛艳春.妊娠期糖尿病对妊娠结局的影响及分析[J].中国计划生育学杂志,2017,25(6):402-404.
[6] 周剑利,刘聪慧,邢军.妊娠期糖尿病患者血脂水平的变化对妊娠结局的影响[J].中国计划生育和妇产科,2016,10(6):10-13.
[7] LIANG Q C,JIN D,LI Y,et al.Mean platelet volume and platelet distribution width in vascular dementia and Alzheimer’s disease[J].Platelets,2014,25(6):433-438.
[8] 陈正林,许烨,曾玉,等.妊娠期糖尿病患者血小板参数的变化[J].临床检验杂志,2014,15(5):377-377.
[9] 孙雪林,徐娜,景丽.妊娠期糖尿病患者血小板指标的变化及分析[J].宁夏医科大学学报,2016,38(10):213-2147.
[10] 黄芝,汤步阳,常琳,等.平均血小板体积变化与2型糖尿病和糖尿病肾病的关系[J].蚌埠医学院学报,2014,39(1):58-60.
[11] 王双,王志梅,杨佳佳,等.凝血功能指标、血小板参数与妊娠晚期子痫前期的关系研究[J].中国全科医学,2018,12(4):444-448.
[12] 李影.妊娠高血压疾病患者血小板参数和凝血指标的改变及临床意义[J].中国医药导报,2013,10(19):78-80.
[2] STEIROPOULOS P,PAPANAS N,NENA E,et al.Mean platelet volume and platelet distribution width in patients with chronic obstructive pulmonary disease the role of comorbidities[J].Angiology,2013,64(7):535-539.
[3] 张丽杰.妊娠期高血压孕妇凝血功能及血小板参数变化与妊娠结局的关系[J].血栓与止血学,2015,12(5):320-321.
[4] SAHIN M S,KIZILIRMAK D.Changes at mean platelet volume and platelet distribution width levels after septoplasty and its correlation with Epworth sleepness scale[J].Journal of Craniofacial Surgery,2017,28(1):71-71.
[5] 卞桂萍,薛艳春.妊娠期糖尿病对妊娠结局的影响及分析[J].中国计划生育学杂志,2017,25(6):402-404.
[6] 周剑利,刘聪慧,邢军.妊娠期糖尿病患者血脂水平的变化对妊娠结局的影响[J].中国计划生育和妇产科,2016,10(6):10-13.
[7] LIANG Q C,JIN D,LI Y,et al.Mean platelet volume and platelet distribution width in vascular dementia and Alzheimer’s disease[J].Platelets,2014,25(6):433-438.
[8] 陈正林,许烨,曾玉,等.妊娠期糖尿病患者血小板参数的变化[J].临床检验杂志,2014,15(5):377-377.
[9] 孙雪林,徐娜,景丽.妊娠期糖尿病患者血小板指标的变化及分析[J].宁夏医科大学学报,2016,38(10):213-2147.
[10] 黄芝,汤步阳,常琳,等.平均血小板体积变化与2型糖尿病和糖尿病肾病的关系[J].蚌埠医学院学报,2014,39(1):58-60.
[11] 王双,王志梅,杨佳佳,等.凝血功能指标、血小板参数与妊娠晚期子痫前期的关系研究[J].中国全科医学,2018,12(4):444-448.
[12] 李影.妊娠高血压疾病患者血小板参数和凝血指标的改变及临床意义[J].中国医药导报,2013,10(19):78-80.