原位电离小型便携式质谱的研究进展
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摘要
原位电离和小型便携式质谱的开发及应用是当前化学测量学领域的研究热点。基于原位电离小型便携式质谱的分析检测技术,无需色谱分离,亦可免除或简化样品前处理过程,突破了传统检测技术操作繁琐、耗时冗长的弊端,可实现样品高灵敏、高通量的现场快速检测,体现了化学测量向快速高效、实时原位、灵敏特异、环境友好等方向发展的重要趋势。本文对原位电离小型便携式质谱的研究进展及在食品安全、消费品安全、公共安全、生命科学、环境监测等相关领域的应用进行了综述,并对其发展趋势和应用前景进行了展望,以期为相关领域研究人员提供技术参考。
The development and application of ambient ionization and miniature mass spectrometry are current research focus in chemical measurements. The analytical technology based on ambient ionization coupled with miniature mass spectrometry can bypass chromatographic separation and eliminate or simplify sample pretreatment process. The protocol breaks through the drawbacks of labor-intensive and time-consuming of traditional analytical methodologies,and can be used for the rapid and on-site analysis with high sensitivity and high throughput. In this paper,research progress of ambient ionization and miniature mass spectrometry as well as their applications in the fields of food safety,consumer product safety,public security,life science and environmental monitoring have been reviewed,and future trends and prospective have been discussed,which may provide a technical guidance for the researchers engaged in relevant fields.
The development and application of ambient ionization and miniature mass spectrometry are current research focus in chemical measurements. The analytical technology based on ambient ionization coupled with miniature mass spectrometry can bypass chromatographic separation and eliminate or simplify sample pretreatment process. The protocol breaks through the drawbacks of labor-intensive and time-consuming of traditional analytical methodologies,and can be used for the rapid and on-site analysis with high sensitivity and high throughput. In this paper,research progress of ambient ionization and miniature mass spectrometry as well as their applications in the fields of food safety,consumer product safety,public security,life science and environmental monitoring have been reviewed,and future trends and prospective have been discussed,which may provide a technical guidance for the researchers engaged in relevant fields.
引文
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