甲状腺结节超声造影及相关病理形态结构研究

详细信息    查看全文 | 推荐本文 |

英文篇名：Study of Pathological Structure and Contrast-enhanced Ultrasonography Features of Thyroid Nodules 作者：陶玲玲 ; 樊金芳 ; 李伟伟 ; 吴敏 ; 陆采葑 ; 周伟 英文作者：TAO Ling-ling;FAN Jin-fang;LI Wei-wei;WU Min;LU Cai-feng;ZHOU Wei;Department of Ultrasound, Ruijin Hospital luwan branch, Medical college of Shanghai Jiaotong University;Department of Pathology, Ruijin Hospital luwan branch, Medical college of Shanghai Jiaotong University;Department of Ultrasound, Ruijin Hospital, Medical college of Shanghai Jiaotong University; 关键词：甲状腺结节 ; 超声造影 ; 病理形态结构 英文关键词：Thyroid nodules;;Contrast-enhanced ultrasound;;Pathological structure 中文刊名：YJTY 英文刊名：Chinese Computed Medical Imaging 机构：上海交通大学医学院附属瑞金医院卢湾分院超声科;上海交通大学医学院附属瑞金医院卢湾分院病理科;上海交通大学医学院附属瑞金医院超声科; 出版日期：2019-02-25 出版单位：中国医学计算机成像杂志 年：2019 期：v.25 基金：上海市黄浦区科研项目基金(No.HKM201704)~~ 语种：中文; 页：YJTY201901018 页数：4 CN：01 ISSN：31-1700/TH 分类号：69-72

摘要

目的:探寻甲状腺可疑结节的周边及内部病理形态结构分析指标与超声造影模式指标之间的相关性。方法:回顾性分析经病理证实的甲状腺结节手术患者共151个结节的病理形态结构指标与超声造影指标。结果:甲状腺结节周边血管粗细及周边组织主要构成在甲状腺良恶性结节组间差异有统计学意义(P<0.05),结节周边组织主要构成、周边血管的粗细程度在有无环形增强组间差异有统计学意义(P <0.05)。良性结节周边多以粗大血管为主,超声造影多提示有环形增强。恶性结节周边多以纤维成分为主,超声造影多提示无环形增强。结论:甲状腺良恶性结节超声造影指标具有一定的病理形态结构基础。
        Purpose: To explore the correlation between peripheral and internal morphological structure characteristics of suspicious thyroid nodules and the parameters of contrast-enhanced ultrasound(CEUS). Methods: One hundred and fifty-one thyroid nodules with pathological and CEUS results were retrospectively analyzed. Results: The size of vessels around thyroid nodules and the main components of peripheral tissues were with statistical significant difference between the benign and malignant nodules(P<0.05). The major components around the nodules and the size of peripheral vessels were with statistical significant difference between the groups with and without annular enhancement(P<0.05). The majority of benign nodules were mainly with large blood vessels around the nodules, and showed annular enhancements on CEUS. The majority of malignant nodules were dominated by fiber components around the nodules, and had no annular enhancement on CEUS. Conclusion: Contrast-enhanced ultrasound parameters of benign and malignant thyroid nodules were related to certain pathological morphological structure.

引文

[1]Parkin DM,Ferlay J,Curado MP et al.Fifty years of cancer incidence:CI5 I-IX.Int J Cancer,2010,127:2918-2927.
    [2]Sun B,Lang L,Zhu X et al.Accuracy of contrast-enhanced ultrasound in the identification of thyroid nodules:a meta-analysis.Int J Clin Exp Med,2015,8:12882-12889.
    [3]Zhang Y,Luo YK,Zhang MB et al.Diagnostic Accuracy of ContrastEnhanced Ultrasound Enhancement Patterns for Thyroid Nodules.Med Sci Monit,2016,22:4755-4764.
    [4]Sun B,Lang L,Zhu X et al.Accuracy of contrast-enhanced ultrasound in the identification of thyroid nodules:a meta-analysis.Int J Clin Exp Med,2015 8:12882-12889.
    [5]陶玲玲,王天翔,李小恩等.常规超声与超声造影联合评分对甲状腺良恶性结节的鉴别诊断价值.临床超声医学杂志,2015,4:227-230.
    [6]陶玲玲,王天翔,沈依等.甲状腺结节超声造影形态学特征初步研究.中国医学计算机成像杂志,2015,21:73-76.
    [7]Schleder S,Janke M,Aqha A et al.Preoperative differentiation of thyroid adenomas and thyroid carcinomas using high resolution contrast-enhancedultrasound(CEUS).Clin Hemorheol Microcirc,2015;61:13-22.
    [8]zhang B,Jiang YX,Liu JB,et al.Utility of contrast-enhanced ultrasound fbr evaluation ofthyroid nodules.Thyroid,2010,20:51-57.
    [9]周明炀,费小春,詹维伟,等.甲状腺微小乳头状癌常见超声表现的病理学基础.中华医学超声杂志(电子版),2014,5:383-387.
    [10]张岩,卢瑞刚,郭瑞君.超微血管成像技术在甲状腺乳头状癌诊断中的应用.中华医学超声杂志(电子版),2017,2:141-144.