地诺前列酮栓与催产素用于足月妊娠促宫颈成熟及引产中的临床效果
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摘要
目的探讨地诺前列酮栓与催产素在足月妊娠促宫颈成熟及引产中的应用价值。方法选取2017年4月至2018年4月仙桃市第一人民医院收治的68例产妇作为研究对象,将其进行奇偶排序分组,34例奇数产妇作为观察组,接受地诺前列酮栓治疗,34例偶数产妇作为对照组,接受催产素治疗。比较两组产妇引产效果及用药前后宫颈成熟度(Bishop)评分、新生儿Apgar评分。结果观察组引产总有效率高于对照组;用药后4 h观察组产妇Bishop评分高于对照组;观察组新生儿出生后各时间段Apgar评分均高于对照组;差异均有统计学意义(均P<0.05)。结论地诺前列酮栓促宫颈成熟效果显著,在确保规则宫缩前提下能够促进宫颈软化,加快产程进展,提高产妇引产成功率,并且具有较高安全性。
Obdective To explore the application value of dinoprostone suppositories and oxytocin in promoting cervical ripening and induced labouri in full-term pregnancy. Methods A total of 68 puerperas admitted in first people's hospital of Xiantao city from April 2017 to April 2018 were selected as subjects, and were divided into the observation group and the control group in odd and even order, with 34 cases as the observation group, treated with dinoprostone suppositories, and with 34 cases of even puerperas selected as the control group, treated with oxytocin. The effects of induced labour, and the cervical ripening score(Bishop)before and after treatment, and newborn score(Apgar) in the two groups were compared. Results The total effective rate of induced labour in the observation group was higher than that in the control group. The Bishop score in the observation group was higher than that in the control group at 4 h after treatment, while the Apgar score in the observation group was higher than that in the control group at each time after birth. The differences were statistically significant(P<0.05). Conclusion Dinoprostone suppositories can significantly promote cervical ripening effect, under the premise of ensuring regular uterine contration, which can promote cervical softening, accelerate the progress of labor, improve the success rate of induced labour, and have higher safety.
Obdective To explore the application value of dinoprostone suppositories and oxytocin in promoting cervical ripening and induced labouri in full-term pregnancy. Methods A total of 68 puerperas admitted in first people's hospital of Xiantao city from April 2017 to April 2018 were selected as subjects, and were divided into the observation group and the control group in odd and even order, with 34 cases as the observation group, treated with dinoprostone suppositories, and with 34 cases of even puerperas selected as the control group, treated with oxytocin. The effects of induced labour, and the cervical ripening score(Bishop)before and after treatment, and newborn score(Apgar) in the two groups were compared. Results The total effective rate of induced labour in the observation group was higher than that in the control group. The Bishop score in the observation group was higher than that in the control group at 4 h after treatment, while the Apgar score in the observation group was higher than that in the control group at each time after birth. The differences were statistically significant(P<0.05). Conclusion Dinoprostone suppositories can significantly promote cervical ripening effect, under the premise of ensuring regular uterine contration, which can promote cervical softening, accelerate the progress of labor, improve the success rate of induced labour, and have higher safety.
引文
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[9]甘焱宁.双球囊与欣普贝生用于羊水过少足月引产促宫颈成熟的临床效果[J].临床医药文献电子杂志,2017,4(65):12844,12846.
[10]张丽祥.双球囊与欣普贝生用于羊水过少足月引产促宫颈成熟的临床对照研究[J].临床医药文献电子杂志,2017,4(45):8747.
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[12]翁碧芬,李筱芸,余艳萍.宫颈球囊、欣普贝生及催产素引产对母婴结局的影响[J].海南医学,2017,28(3):414-416.
[2]刘海燕,叶旭萍,杨燕,等.欣普贝生用于足月胎膜早破低宫颈评分引产的效果观察[J].现代妇产科进展,2017,26(3):194-198.
[3]常林利,刘晓蓉,刘俊,等.欣普贝生促宫颈成熟后对阴道分娩、围产儿结局的影响[J].中国妇幼健康研究,2016,27(4):479-481.
[4]孙桂蓉.催产素联合COOK宫颈扩张球囊用于足月妊娠引产的效果分析[J].中国妇幼保健,2016,31(3):646-648.
[5]顾逢春,凌静,朱玉莲,等.欣普贝生与催产素用于足月妊娠促宫颈成熟及引产中的临床效果比较[J].北方药学,2017,14(10):106,105.
[6]宁飞燕.欣普贝生和米索前列醇用于足月妊娠促宫颈成熟的效果比较[J].河南医学研究,2017,26(16):2957-2958.
[7]孙连华.米索前列醇与催产素用于足月妊娠促宫颈成熟与引产的效果对比观察[J].中国疗养医学,2017,26(11):1216-1218.
[8]聂乐凯,陈文惠.足月妊娠引产应用欣普贝生、缩宫素、米索前列醇的效果比较[J].实用妇科内分泌杂志(电子版),2017,4(2):114-115.
[9]甘焱宁.双球囊与欣普贝生用于羊水过少足月引产促宫颈成熟的临床效果[J].临床医药文献电子杂志,2017,4(65):12844,12846.
[10]张丽祥.双球囊与欣普贝生用于羊水过少足月引产促宫颈成熟的临床对照研究[J].临床医药文献电子杂志,2017,4(45):8747.
[11]曹妮.欣普贝生对宫颈未成熟足月妊娠产妇分娩方式及妊娠结局的影响[J].中国妇幼保健,2017,32(21):5244-5246.
[12]翁碧芬,李筱芸,余艳萍.宫颈球囊、欣普贝生及催产素引产对母婴结局的影响[J].海南医学,2017,28(3):414-416.