高强度聚焦超声消融应用于子宫腺肌病合并子宫肌瘤治疗中的近期疗效与安全性观察
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摘要
目的探讨高强度聚焦超声消融应用于子宫腺肌病合并子宫肌瘤治疗中的近期疗效与安全性。方法选择2016年1月—2017年12月该院收治的子宫腺肌病合并子宫肌瘤患者72例,该组患者均行高强度聚焦超声消融治疗。结果治疗后6个月,该组患者病灶体积(60.8±12.5)cm~3、子宫体积(200.5±15.6)cm~3、痛经评分(5.2±0.5)分与经量评分(4.5±1.5)分均低于对照组(20.5±10.8)cm~3、(152.2±10.5)cm~3、(1.7±1.0)分、(2.5±1.2)分(t=6.526,5.656,6.052,4.856,P<0.05)。该组72例患者根据国际介入放射治疗协会并发症分级标准(SIR)分级显示,A级63例,B级9例,无C级及C级以上并发症。结论高强度聚焦超声消融治疗子宫腺肌病合并子宫肌瘤近期疗效满意,且安全性较佳,适于应用。
Objective To investigate the short-term efficacy and safety of high-intensity focused ultrasound ablation in the treatment of adenomyosis with uterine fibroids. Methods 72 patients with adenomyosis and uterine fibroids admitted to our hospital from January 2016 to December 2017 were enrolled. All patients underwent high-intensity focused ultrasound ablation. Results At 6 months after treatment, the lesion volume(60.8±12.5)cm~3, uterine volume(200.5±15.6)cm~3,dysmenorrhea score(5.2±0.5)points and longitude score(4.5±1.5)points were lower than that of control group(20.5±10.8)cm~3,(152.2±10.5)cm~3,(1.7±1.0)points, and(2.5±1.2)points(t=6.526, 5.656, 6.052, 4.856, P<0.05). According to the International Interventional Radiotherapy Association's Complication Grading Criteria(SIR), 72 patients in this group showed 63 cases of grade A, 9 cases of grade B, and no complications of grade C and above. Conclusion High-intensity focused ultrasound ablation for adenomyosis with uterine fibroids is satisfactory, and it is safe and suitable for application.
Objective To investigate the short-term efficacy and safety of high-intensity focused ultrasound ablation in the treatment of adenomyosis with uterine fibroids. Methods 72 patients with adenomyosis and uterine fibroids admitted to our hospital from January 2016 to December 2017 were enrolled. All patients underwent high-intensity focused ultrasound ablation. Results At 6 months after treatment, the lesion volume(60.8±12.5)cm~3, uterine volume(200.5±15.6)cm~3,dysmenorrhea score(5.2±0.5)points and longitude score(4.5±1.5)points were lower than that of control group(20.5±10.8)cm~3,(152.2±10.5)cm~3,(1.7±1.0)points, and(2.5±1.2)points(t=6.526, 5.656, 6.052, 4.856, P<0.05). According to the International Interventional Radiotherapy Association's Complication Grading Criteria(SIR), 72 patients in this group showed 63 cases of grade A, 9 cases of grade B, and no complications of grade C and above. Conclusion High-intensity focused ultrasound ablation for adenomyosis with uterine fibroids is satisfactory, and it is safe and suitable for application.
引文
[1]郭慧宁.高强度超声聚焦治疗子宫肌瘤的临床分析[J]系统医学,2018,3(10):109-111.
[2]王丽萍,柳弘彦,雷玉珍.高强度聚焦超声在子宫腺肌症治疗中的临床价值[J].中国冶金工业医学杂志,2018,35(1):4-5.
[3]颜容,申恒春.高强度聚焦超声治疗子宫腺肌症的临床疗效[J].广西医学,2018,40(9):1099-1101.
[4]崔运能,田橄,陈向东,等.高强度聚焦超声治疗子宫肌瘤及子宫腺肌瘤术后早期并发症的MR表现[J].临床放射学杂志,2018,37(3):461-465.
[5]谢幸,苟文丽.妇产科学[M].第8版.北京:人民卫生出版社,2013,310.
[6]罗爽,王艳,何佳.高强度聚焦超声消融联合孕三烯酮治疗子宫腺肌病的疗效评价[J].重庆医学,2018,47(2):170-172.
[7]王莹.探讨子宫动脉栓塞治疗和手术切除治疗对子宫腺肌症的临床效果[J].系统医学,2017,2(20):98-101.
[8]赵成,赵卫东,周虎,等.高强度聚焦超声联合GnRH-a治疗子宫腺肌症的临床研究[J].安徽医科大学学报,201752(12):1839-1844.
[9]周英杰,阎雪,张玉,等.声触诊组织定性成像技术在高强度聚焦超声消融子宫腺肌瘤疗效评价中的作用[J].中国超声医学杂志,2017,33(7):663-665.
[10]牟燕,刘晓芳,何佳.高强度聚焦超声治疗子宫肌瘤和子宫腺肌病后盆腔黏连情况分析[J].重庆医学,2016,45(10):1339-1342.
[11]杨欣,王晓娜,胡美丽,等.高强度聚焦超声消融子宫腺肌症48例临床疗效观察[J].河北医科大学学报,201637(1):83-86.
[12]郑媛媛,郑素娟,王润萍,等.高强度聚焦超声治疗子宫腺肌瘤28例[J].河南医学高等专科学校学报,2018,30(2):103-105.
[2]王丽萍,柳弘彦,雷玉珍.高强度聚焦超声在子宫腺肌症治疗中的临床价值[J].中国冶金工业医学杂志,2018,35(1):4-5.
[3]颜容,申恒春.高强度聚焦超声治疗子宫腺肌症的临床疗效[J].广西医学,2018,40(9):1099-1101.
[4]崔运能,田橄,陈向东,等.高强度聚焦超声治疗子宫肌瘤及子宫腺肌瘤术后早期并发症的MR表现[J].临床放射学杂志,2018,37(3):461-465.
[5]谢幸,苟文丽.妇产科学[M].第8版.北京:人民卫生出版社,2013,310.
[6]罗爽,王艳,何佳.高强度聚焦超声消融联合孕三烯酮治疗子宫腺肌病的疗效评价[J].重庆医学,2018,47(2):170-172.
[7]王莹.探讨子宫动脉栓塞治疗和手术切除治疗对子宫腺肌症的临床效果[J].系统医学,2017,2(20):98-101.
[8]赵成,赵卫东,周虎,等.高强度聚焦超声联合GnRH-a治疗子宫腺肌症的临床研究[J].安徽医科大学学报,201752(12):1839-1844.
[9]周英杰,阎雪,张玉,等.声触诊组织定性成像技术在高强度聚焦超声消融子宫腺肌瘤疗效评价中的作用[J].中国超声医学杂志,2017,33(7):663-665.
[10]牟燕,刘晓芳,何佳.高强度聚焦超声治疗子宫肌瘤和子宫腺肌病后盆腔黏连情况分析[J].重庆医学,2016,45(10):1339-1342.
[11]杨欣,王晓娜,胡美丽,等.高强度聚焦超声消融子宫腺肌症48例临床疗效观察[J].河北医科大学学报,201637(1):83-86.
[12]郑媛媛,郑素娟,王润萍,等.高强度聚焦超声治疗子宫腺肌瘤28例[J].河南医学高等专科学校学报,2018,30(2):103-105.