五味子胶囊提取工艺研究
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摘要
目的研究五味子胶囊的水提工艺。方法以料液比、提取时间、提取次数、浸泡时间为试验因素,各因素分别设计3个水平,采用L9(34)正交设计,以出膏率和总皂苷、总多糖含量作为筛选指标。结果最佳提取工艺为:提取次数3次,提取时间1 h,加水量6倍。结论本工艺操作简便、快捷、节约成本,为质量标准研究奠定了基础。
Objective The water extraction process of Schisandra capsule was studied. Methods The ratio of material to liquid, extraction time, extraction times and soaking time were taken as experimental factors. Each factor was designed with 3 levels. L9(34) orthogonal design was used. The rate of out of paste and total saponins and polysaccharides were used as screening indicators. Results The optimum extraction process was as follows: extraction times 3 times, extraction time 1 h, and water volume 6 times. Conclusion The process is simple, quick and cost saving, which lays the foundation for quality standard research.
Objective The water extraction process of Schisandra capsule was studied. Methods The ratio of material to liquid, extraction time, extraction times and soaking time were taken as experimental factors. Each factor was designed with 3 levels. L9(34) orthogonal design was used. The rate of out of paste and total saponins and polysaccharides were used as screening indicators. Results The optimum extraction process was as follows: extraction times 3 times, extraction time 1 h, and water volume 6 times. Conclusion The process is simple, quick and cost saving, which lays the foundation for quality standard research.
引文
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[2]孙福仁,焦安妮.人参五味子片保护小鼠酒精性肝细胞损伤研究[J].人参研究,2015,27(3):8-9.
[3]柳旭,付佳,王春梅,等.北五味子与人参配伍前后主要化学成分的变化研究[J].中药材,2017,40(9):2141-2144.
[4]王瑞,吴桐,刘悦,等.远志和蜜远志对小鼠胃肠的急性毒性作用[J].中国中医药现代远程教育,2018,16(8):88-90.
[5]姚梦杰,吕金朋,张乔,等.人参化学成分及药理作用研究[J].吉林中医药,2017,37(12):1261-1263.
[6]李珊珊,祁玉丽,华梅,等.北五味子多糖的分离纯化及抗氧化活性研究[J].食品工业,2018,39(4):233-237.
[7]翟海容.益元康方中西洋参总皂苷、总多糖提取纯化工艺研究[D].郑州:河南中医学院,2015.
[8]赵立军,崔敏,储君,等.复方中药增免颗粒药材提取工艺研究[J].中兽医学杂志,2017,8(3):10-12.
[9]龙晓燕,叶林,蔡林军,等.枸杞子残渣中多糖的提取工艺研究[J].食品工业科技,2017,38(9):248-251.
[10]梁艳君,谭喜梅,黄燕琼,等.红豆蔻等3味山姜属中药的提取工艺研究[J].浙江中医杂志,2017,52(12):920-922.
[11]王玉堂.人参中人参皂苷的提取、分离和测定[D].长春:吉林大学,2008.
[12]黄涛阳,王晖,刘华,等.通脉降脂分散片中总皂苷溶出度紫外自身对照检测方法研究[J].中药材,2010,33(5):819-821.
[13]P.C.ANDERSON,F.J.RICH,STANISLAV BORISOV.Mapping the South Atlantic Anomaly continuously over27 years[J].Journal of Atmospheric and Solar-Terrestrial Physics,2018,14(5):124-129.
[14]李海欧,陈琪,林英华,等.正交设计优化黄芪多糖提取工艺[J].畜牧与饲料科学,2018,39(1):1-3.
[15]姚亮,彭代银,俞年军,等.正交试验优化霍山米斛总多糖提取工艺[J].安徽中医药大学学报,2016,35(4):83-87.
[16]韩红玉.西洋参总皂苷和总多糖体外免疫学评价[D].郑州:河南中医药大学,2016.
[17]刘姝男.人参多糖及其组分抗老年痴呆的有效性研究[D].长春:吉林大学,2014.