三通推拿法联合骶管封闭治疗腰椎间盘突出症临床研究
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摘要
目的:观察三通推拿法联合骶管封闭治疗腰椎间盘突出症的临床疗效。方法:选取136例腰椎间盘突出症患者,采用随机数字表法分为观察组与对照组,每组68例。2组均采用一般治疗,对照组联合骶管封闭治疗,观察组在对照组基础上联合三通推拿法治疗。对比2组临床疗效、疼痛指数、血浆血栓素B2及血清炎症因子水平。结果:总有效率观察组95.59%,高于对照组的82.35%,差异有统计学意义(P <0.05)。治疗后,2组疼痛指数及血浆血栓素B2水平与治疗前比较,差异均有统计学意义(P <0.05);观察组疼痛指数高于对照组,血浆血栓素B2水平低于对照组,差异均有统计学意义(P <0.05)。治疗后,2组肿瘤坏死因子-α(TNF-α)、白细胞介素-6 (IL-6)及C-反应蛋白(CRP)水平均较治疗前下降,差异均有统计学意义(P <0.05);观察组3项炎症因子水平均低于对照组,差异均有统计学意义(P <0.05)。结论:三通推拿法联合骶管封闭治疗腰椎间盘突出症,能提高临床疗效,减轻疼痛,降低患者的血浆血栓素B2及血清炎症因子水平。
Objective:To observe the clinical effect of Santong Tuina method combined with sacral canal blocking in the treatment of lumbar intervertebral disc herniation. Methods:A total of 136 patients with lumbar intervertebral disc herniation were selected and divided into the observation group and the control group according to random number table method,68 patients in each group. The two groups were treated with general therapy, the control group was additionally treated with sacral canal blocking,and the observation group treated with Santong Tuina method based on the treatment of the control group. Clinical effect, pain degree and levels of plasma thrombin B2 and inflammatory factors in serum were compared between the two groups. Results:The total effective rate was 95.59% in the observation group,higher than that of 82.35%in the control group,the difference being significant(P < 0.05). After treatment,pain degree and levels of plasma thrombin B2 in the two groups were compared with those before treatment,differences being significant(P < 0.05). The pain degree in the observation group was higher than that in the control group,and the level of plasma thrombin B2 was lower than that in the control group, differences being significant(P < 0.05). After treatment, levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in both groups were decreased when compared with those before treatment,differences being significant(P < 0.05). The levels of the above three inflammatory factors in the observation group were lower than those in the control group, differences being significant(P < 0.05). Conclusion: The therapy of Santong Tuina method combined with sacral canal blocking in the treatment of lumbar intervertebral disc herniation,can improve the clinical effect,lessen pain,and reduce the levels of plasma thrombin B2 and inflammatory factors in serum.
Objective:To observe the clinical effect of Santong Tuina method combined with sacral canal blocking in the treatment of lumbar intervertebral disc herniation. Methods:A total of 136 patients with lumbar intervertebral disc herniation were selected and divided into the observation group and the control group according to random number table method,68 patients in each group. The two groups were treated with general therapy, the control group was additionally treated with sacral canal blocking,and the observation group treated with Santong Tuina method based on the treatment of the control group. Clinical effect, pain degree and levels of plasma thrombin B2 and inflammatory factors in serum were compared between the two groups. Results:The total effective rate was 95.59% in the observation group,higher than that of 82.35%in the control group,the difference being significant(P < 0.05). After treatment,pain degree and levels of plasma thrombin B2 in the two groups were compared with those before treatment,differences being significant(P < 0.05). The pain degree in the observation group was higher than that in the control group,and the level of plasma thrombin B2 was lower than that in the control group, differences being significant(P < 0.05). After treatment, levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in both groups were decreased when compared with those before treatment,differences being significant(P < 0.05). The levels of the above three inflammatory factors in the observation group were lower than those in the control group, differences being significant(P < 0.05). Conclusion: The therapy of Santong Tuina method combined with sacral canal blocking in the treatment of lumbar intervertebral disc herniation,can improve the clinical effect,lessen pain,and reduce the levels of plasma thrombin B2 and inflammatory factors in serum.
引文
[1]马宝佳.针刀联合骶管封闭治疗腰椎间盘突出症537例[J].人民军医,2014,57(10):1121.
[2]顾罗加,孙文里,潘浩.中医推拿联合中药外敷治疗腰椎间盘突出症临床疗效[J].辽宁中医杂志,2015,42(1):100-102.
[3]胡有谷.腰椎间盘突出症[M].3版.北京:人民卫生出版社,2004:149-163.
[4]国家中医药管理局.ZY/T001.1~001.9-94中医病证诊断疗效标准[S].南京:南京大学出版社,1994:201.
[5]谭克平,刘光国,姚旭,等.针药结合对腰椎间盘突出症患者血清细胞因子、MDA、SOD及血浆血栓素B2水平的影响[J].中华中医药学刊,2016,34(6):1523-1526.
[6]曹越,章薇.针药结合对寒湿证腰椎间盘突出症患者血清IL-6和TNF-α的影响[J].针灸临床杂志,2016,32(1):8-10.
[7]侯桂红,李倩,谢燕.椎间盘组织中炎症因子水平、MMPs/TIMPs表达与腰椎间盘突出症的关系研究[J].中国实验诊断学,2018,22(5):791-794.
[8]杨艳,孙赟,李蕊,等.经皮椎间孔镜治疗腰椎间盘突出症围手术期的护理[J].中华全科医学,2016,14(2):317-319.
[9]吴建民,牛爱春,邱偲泓,等.改良骶管封闭疗法联合小针刀治疗腰椎间盘突出症的临床研究[J].中华中医药杂志,2017,32(8):3855-3857.
[10]武占红,王鹏,祁志敏,等.推拿联合功能训练对康复期腰椎间盘突出症腰椎功能的影响[J].长春中医药大学学报,2015,31(6):1228-1229,1230.
[11]梅莎莎,宋恩峰,项琼.中西医结合治疗腰椎间盘突出症临床观察[J].湖北中医药大学学报,2015,17(5):86-87.
[12]莫伟,许金海,叶洁,等.腰椎间盘突出症中医治疗方法的研究进展[J].中国中医急症,2016,25(3):474-476.
[2]顾罗加,孙文里,潘浩.中医推拿联合中药外敷治疗腰椎间盘突出症临床疗效[J].辽宁中医杂志,2015,42(1):100-102.
[3]胡有谷.腰椎间盘突出症[M].3版.北京:人民卫生出版社,2004:149-163.
[4]国家中医药管理局.ZY/T001.1~001.9-94中医病证诊断疗效标准[S].南京:南京大学出版社,1994:201.
[5]谭克平,刘光国,姚旭,等.针药结合对腰椎间盘突出症患者血清细胞因子、MDA、SOD及血浆血栓素B2水平的影响[J].中华中医药学刊,2016,34(6):1523-1526.
[6]曹越,章薇.针药结合对寒湿证腰椎间盘突出症患者血清IL-6和TNF-α的影响[J].针灸临床杂志,2016,32(1):8-10.
[7]侯桂红,李倩,谢燕.椎间盘组织中炎症因子水平、MMPs/TIMPs表达与腰椎间盘突出症的关系研究[J].中国实验诊断学,2018,22(5):791-794.
[8]杨艳,孙赟,李蕊,等.经皮椎间孔镜治疗腰椎间盘突出症围手术期的护理[J].中华全科医学,2016,14(2):317-319.
[9]吴建民,牛爱春,邱偲泓,等.改良骶管封闭疗法联合小针刀治疗腰椎间盘突出症的临床研究[J].中华中医药杂志,2017,32(8):3855-3857.
[10]武占红,王鹏,祁志敏,等.推拿联合功能训练对康复期腰椎间盘突出症腰椎功能的影响[J].长春中医药大学学报,2015,31(6):1228-1229,1230.
[11]梅莎莎,宋恩峰,项琼.中西医结合治疗腰椎间盘突出症临床观察[J].湖北中医药大学学报,2015,17(5):86-87.
[12]莫伟,许金海,叶洁,等.腰椎间盘突出症中医治疗方法的研究进展[J].中国中医急症,2016,25(3):474-476.