产前超声对不同年龄阶段孕妇胎儿畸形筛查价值分析
|
摘要
目的探究分析产前超声对不同年龄阶段孕妇胎儿畸形筛查价值。方法选择于我院行产前超声检查的孕妇18256例作为研究对象,以年龄分组,共分成6组:<20岁组312例,20～24岁组5023例、25～29岁组7836例、30～34岁组3940例、35～39岁组773例及> 39岁组312例。记录并分析不同年龄段孕妇经产前超声筛查的胎儿畸形检出情况。结果 <20岁组的畸形胎儿检出20例、检出率6. 41%、20～24岁检出163例、检出率3. 25%、25～29岁检出169例、检出率2. 16%、30～34岁检出20例、检出率2. 31%、35～39岁检出30例、检出率3. 88%、> 39岁检出27例、检出率7. 26%。<20岁及> 39岁的畸形胎儿检出率明显高于其他年龄组别(P <0. 05)。> 39岁的胎儿以多发畸形为主,其他组别主要以单发畸形为主(P <0. 05)。胎儿的畸形类型以泌尿生殖系统畸形为主,明显高于其他类型(P <0. 05)。泌尿生殖系统畸形里主要以肾脏畸形为主,其中167例为肾积水。结论胎儿畸形由多种因素导致,孕妇年龄过小胎儿容易出现严重畸形;孕妇年龄过大胎儿容易出现多发畸形,增加先天性心脏畸形和神经系统畸形的发生率。
Objective To explore the value of prenatal ultrasound in screening fetal malformations in pregnant women of different ages. Methods A total of 18,256 pregnant women who underwent prenatal ultrasound examination in our hospital were selected as subjects. They were divided into 6 groups according to age: 312 patients be less than 20 age group 5023 patients in the20 ～ 24 age group,7836 patients in the 25 ～ 29 age group,and 3940 in the 30 ～ 34 age group. For example,773 patients in the35 ～ 39 age group and 312 patients in the 39-year-old group. The detection and analysis of fetal malformation by prenatal ultrasound screening in pregnant women of different ages were recorded and analyzed. Results In the 20-year-old group,20 cases of malformed fetuses were detected,the detection rate was 6. 41%,163 cases were detected at 20 to 24 years old,the detection rate was 3. 25%,and 169 cases were detected at 25 to 29 years old. The detection rate was 2. 16%,30 ～ At the age of 34,91 cases were detected,the detection rate was 2. 31%,30 cases were detected at 35 to 39 years old,the detection rate was 3. 88%,and27 cases were detected at > 39 years old,and the detection rate was 7. 26%. The detection rate of malformed fetuses < 20 years old and > 39 years old was significantly higher than other age groups( P < 0. 05). > 39-year-old fetuses were predominantly multiple malformations,and other groups were predominantly single-head deformities( P < 0. 05). The type of malformation of the fetus was mainly genitourinary malformation,which was significantly higher than other types( P < 0. 05). The genitourinary malformations are mainly caused by kidney malformations,including hydronephrosis. Conclusion Fetal malformation is caused by many factors. Pregnant women are too old to be severely deformed. Pregnant women are prone to multiple malformations and increase the incidence of congenital heart malformations and nervous system malformations.
Objective To explore the value of prenatal ultrasound in screening fetal malformations in pregnant women of different ages. Methods A total of 18,256 pregnant women who underwent prenatal ultrasound examination in our hospital were selected as subjects. They were divided into 6 groups according to age: 312 patients be less than 20 age group 5023 patients in the20 ～ 24 age group,7836 patients in the 25 ～ 29 age group,and 3940 in the 30 ～ 34 age group. For example,773 patients in the35 ～ 39 age group and 312 patients in the 39-year-old group. The detection and analysis of fetal malformation by prenatal ultrasound screening in pregnant women of different ages were recorded and analyzed. Results In the 20-year-old group,20 cases of malformed fetuses were detected,the detection rate was 6. 41%,163 cases were detected at 20 to 24 years old,the detection rate was 3. 25%,and 169 cases were detected at 25 to 29 years old. The detection rate was 2. 16%,30 ～ At the age of 34,91 cases were detected,the detection rate was 2. 31%,30 cases were detected at 35 to 39 years old,the detection rate was 3. 88%,and27 cases were detected at > 39 years old,and the detection rate was 7. 26%. The detection rate of malformed fetuses < 20 years old and > 39 years old was significantly higher than other age groups( P < 0. 05). > 39-year-old fetuses were predominantly multiple malformations,and other groups were predominantly single-head deformities( P < 0. 05). The type of malformation of the fetus was mainly genitourinary malformation,which was significantly higher than other types( P < 0. 05). The genitourinary malformations are mainly caused by kidney malformations,including hydronephrosis. Conclusion Fetal malformation is caused by many factors. Pregnant women are too old to be severely deformed. Pregnant women are prone to multiple malformations and increase the incidence of congenital heart malformations and nervous system malformations.
引文
[1]唐敏,宋建琼,刘梅川,等.产前超声筛查不同年龄段孕妇胎儿畸形的差异性分析[J].临床超声医学杂志,2018,20(1):50-53.
[2] Martínez-Payo C,Cabezas E,Nieto Y,et al. Detection of singleumbilical artery in the first trimester ultrasound:its value as amarker of fetal malformation[OL]. Ultrasound Obstet Gynecol,2014,44(S1):548729.
[3] Werner H,Rolo LC,Araujo EJ,et al. Manufacturing models offetal malformations built from 3-dimensional ultrasound,magneticresonance imaging,and computed tomography scan data[J]. Ul-trasound Q,2014,30(1):69-75.
[4]邹波,张莉超,施丹华.孕妇年龄风险与胎儿染色体异常的相关性分析[J].中华医学遗传学杂志,2015,32(1):125-127.
[5] Akgun H,Basbug M,Ozgun MT,et al. Correlation between pre-natal ultrasound and fetal autopsy findings on urinary system a-nomalies terminated in the second trimester.[J]. Prenatal Diag-nosis,2014,34(3):285-290.
[6]邱思花,赖加京,陈淑金.超声筛查在胎儿肢体畸形诊断中的临床应用[J].医学影像学杂志,2013,23(11):1843-1846.
[7]刘满荣,唐建华,丁可,等. 17932例中晚期孕妇产前超声检查结果分析[J].中国妇幼保健,2013,28(1):32-33.
[8]朱智兰,关丽.超声检查在产科临床胎儿异常状况诊断中的价值[J].世界最新医学信息文摘,2016,16(9):157.
[9] Asplin N,Wessel H,Marions L,et al. Pregnancy terminationdue to fetal anomaly:women's reactions,satisfaction and experi-ences of care[J]. Ultrasound Obstet Gynecol,2014,30(6):620-627.
[10]汪芷先,林小影,孟卓,等.采用超声检测不同年龄段孕妇的胎儿颈项透明层的对比分析[J].临床医学工程,2017,24(10):1341-1342.
[11] Volpe P,Contro E,Fanelli T,et al. Appearance of fetal posteri-or fossa at 11~14 weeks in fetuses with Dandy-Walker malfor-mation or chromosomal anomalies[J]. Ultrasound Obstet Gyne-col,2016,47(6):720-725.
[12]张淑美,赵志强.畸形胎儿763例超声诊断分析[J].影像技术,2014,26(4):7-9.
[13] Kunisaki SM,Ehrenbergbuchner S,Dillman JR,et al. Vanis-hing fetal lung malformations:prenatal sonographic characteris-tics and postnatal outcomes[J]. J Pediatr Surg,2015,50(6):978-982.
[14]郭建红.超声诊断胎儿发育异常的临床价值[J].世界最新医学信息文摘,2015,15(8):145-146.
[15]张丹江.胎儿系统超声检查与常规产科超声检查的对比分析[J].临床医学研究与实践,2017,2(34):129-130.
[16]何冠南,罗红,杨家翔.孕11~13周+6产前超声筛查胎儿肢体畸形的价值[J].中国医学影像学杂志,2014,22(8):634-637.
[2] Martínez-Payo C,Cabezas E,Nieto Y,et al. Detection of singleumbilical artery in the first trimester ultrasound:its value as amarker of fetal malformation[OL]. Ultrasound Obstet Gynecol,2014,44(S1):548729.
[3] Werner H,Rolo LC,Araujo EJ,et al. Manufacturing models offetal malformations built from 3-dimensional ultrasound,magneticresonance imaging,and computed tomography scan data[J]. Ul-trasound Q,2014,30(1):69-75.
[4]邹波,张莉超,施丹华.孕妇年龄风险与胎儿染色体异常的相关性分析[J].中华医学遗传学杂志,2015,32(1):125-127.
[5] Akgun H,Basbug M,Ozgun MT,et al. Correlation between pre-natal ultrasound and fetal autopsy findings on urinary system a-nomalies terminated in the second trimester.[J]. Prenatal Diag-nosis,2014,34(3):285-290.
[6]邱思花,赖加京,陈淑金.超声筛查在胎儿肢体畸形诊断中的临床应用[J].医学影像学杂志,2013,23(11):1843-1846.
[7]刘满荣,唐建华,丁可,等. 17932例中晚期孕妇产前超声检查结果分析[J].中国妇幼保健,2013,28(1):32-33.
[8]朱智兰,关丽.超声检查在产科临床胎儿异常状况诊断中的价值[J].世界最新医学信息文摘,2016,16(9):157.
[9] Asplin N,Wessel H,Marions L,et al. Pregnancy terminationdue to fetal anomaly:women's reactions,satisfaction and experi-ences of care[J]. Ultrasound Obstet Gynecol,2014,30(6):620-627.
[10]汪芷先,林小影,孟卓,等.采用超声检测不同年龄段孕妇的胎儿颈项透明层的对比分析[J].临床医学工程,2017,24(10):1341-1342.
[11] Volpe P,Contro E,Fanelli T,et al. Appearance of fetal posteri-or fossa at 11~14 weeks in fetuses with Dandy-Walker malfor-mation or chromosomal anomalies[J]. Ultrasound Obstet Gyne-col,2016,47(6):720-725.
[12]张淑美,赵志强.畸形胎儿763例超声诊断分析[J].影像技术,2014,26(4):7-9.
[13] Kunisaki SM,Ehrenbergbuchner S,Dillman JR,et al. Vanis-hing fetal lung malformations:prenatal sonographic characteris-tics and postnatal outcomes[J]. J Pediatr Surg,2015,50(6):978-982.
[14]郭建红.超声诊断胎儿发育异常的临床价值[J].世界最新医学信息文摘,2015,15(8):145-146.
[15]张丹江.胎儿系统超声检查与常规产科超声检查的对比分析[J].临床医学研究与实践,2017,2(34):129-130.
[16]何冠南,罗红,杨家翔.孕11~13周+6产前超声筛查胎儿肢体畸形的价值[J].中国医学影像学杂志,2014,22(8):634-637.