行气祛瘀汤用于子宫腺肌病患者治疗中的临床效果
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摘要
目的研究分析在子宫腺肌病患者中运用行气祛瘀汤治疗的效果。方法方便选取在该院接受治疗的确诊为子宫腺肌病患者,选取时间段为2016年5月—2017年5月,病例数为60例。通过随机数字表格法分组,平均分成对照组和观察组各30例。对照组患者接受西药孕三烯酮治疗,观察组接受中药行气祛瘀汤治疗,分析两组患者的治疗效果及复发情况。结果观察组中患者的总疗效率为96.67%,对照组中患者的总疗效率为70.00%,组间差异有统计学意义(χ~2=7.195,P<0.05)。治疗后1年内观察组复发率为3.33%,对照组复发率为20.00%,组间差异有统计学意义(χ~2=12.364,P<0.05)。治疗前观察组中患者的血CA125(94.98±43.76)U/mL显著高于对照组(37.32±20.65)U/mL(t=16.254,P<0.05),而治疗后观察组患者的血CA125(26.98±3.65)U/mL与对照组不存在显著差异(23.65±6.32)U/mL(t=3.517,P>0.05)。观察组的血CA125变化情况显著优于对照组(P<0.05);在子宫体积方面,观察组(666.43±321.32)mm3和对照组患者(661.43±322.65)mm3不存在显著差异(t=2.468,P>0.05),而治疗后观察组的子宫体积(623.65±16.76)mm3显著小于对照组(611.65±134.21)mm3以及治疗前阶段(t=19.413,P<0.05)。结论临床上针对子宫腺肌病患者采用行气祛瘀汤治疗效果显著,用药后患者的病情显著改善,且复发率低,具有较高的临床推广价值。
Objective To study the effect of using Xingqi Quyu Decoction in patients with adenomyosis. Methods Patients diagnosed with adenomyosis were convenient selected for treatment in our hospital. The time period was from May 2016 to May 2017, and the number of cases was 60. They were grouped by random number table method and divided into 30 groups of control group and observation group each. The patients in the control group received western medicine gestrinone treatment, and the observation group received Chinese medicine Xingqi Quyu Decoction to analyze the treatment effect and recurrence of the two groups. Results The total response rate was 96.67% in the observation group and 70.00% in the control group. The difference between the groups was statistically significant(χ~2=7.195, P<0.05). The recurrence rate of the observation group was 3.33% within 1 year after treatment, and the recurrence rate of the control group was 20.00%. The difference between the groups was statistically significant(χ~2=12.364, P<0.05). The blood CA125(94.98±43.76) U/mL of the patients in the observation group before treatment was significantly higher than that of the control group(37.32±20.65) U/mL(t=16.254, P<0.05), and the patients in the observation group after treatment. The blood CA125(26.98±3.65) U/mL was not significantly different from the control group(23.65±6.32) U/mL(t=3.517, P>0.05). The change of blood CA125 in the observation group was significantly better than that in the control group(P<0.05). There was no significant difference in the uterine volume between the observation group(666.43±321.32) mm3 and the control group(661.43±322.65) mm3(t=2.468, P>0.05), and the uterus volume(623.65±16.76) mm3 of the observation group after treatment was significantly smaller than that of the control group(611.65±134.21) mm3 and the pre-treatment stage(t=19.413, P<0.05). Conclusion Clinically, the treatment of adenomyosis patients with Xingqi Quyu Decoction has a significant effect. After treatment, the patient's condition is significantly improved, and the recurrence rate is low, which has a high clinical promotion value.
Objective To study the effect of using Xingqi Quyu Decoction in patients with adenomyosis. Methods Patients diagnosed with adenomyosis were convenient selected for treatment in our hospital. The time period was from May 2016 to May 2017, and the number of cases was 60. They were grouped by random number table method and divided into 30 groups of control group and observation group each. The patients in the control group received western medicine gestrinone treatment, and the observation group received Chinese medicine Xingqi Quyu Decoction to analyze the treatment effect and recurrence of the two groups. Results The total response rate was 96.67% in the observation group and 70.00% in the control group. The difference between the groups was statistically significant(χ~2=7.195, P<0.05). The recurrence rate of the observation group was 3.33% within 1 year after treatment, and the recurrence rate of the control group was 20.00%. The difference between the groups was statistically significant(χ~2=12.364, P<0.05). The blood CA125(94.98±43.76) U/mL of the patients in the observation group before treatment was significantly higher than that of the control group(37.32±20.65) U/mL(t=16.254, P<0.05), and the patients in the observation group after treatment. The blood CA125(26.98±3.65) U/mL was not significantly different from the control group(23.65±6.32) U/mL(t=3.517, P>0.05). The change of blood CA125 in the observation group was significantly better than that in the control group(P<0.05). There was no significant difference in the uterine volume between the observation group(666.43±321.32) mm3 and the control group(661.43±322.65) mm3(t=2.468, P>0.05), and the uterus volume(623.65±16.76) mm3 of the observation group after treatment was significantly smaller than that of the control group(611.65±134.21) mm3 and the pre-treatment stage(t=19.413, P<0.05). Conclusion Clinically, the treatment of adenomyosis patients with Xingqi Quyu Decoction has a significant effect. After treatment, the patient's condition is significantly improved, and the recurrence rate is low, which has a high clinical promotion value.
引文
[1]张巧霞.腹腔镜下子宫腺肌病病灶切除术治疗子宫腺肌病效果观察[J].疾病监测与控制, 2016, 10(7):583-584.
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[3]胡李萍.祛瘀消异汤用于子宫腺肌病治疗中的临床效果[J].内蒙古中医药, 2016, 35(14):3-4.
[4]李娟,张小妹,王丹.补肾祛瘀、行气止痛结合穴位烫熨治疗痛经的临床研究[J].光明中医, 2017, 32(17):2449-2451.
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[6]赵蓉,顾玉婵,王丽梅,等.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病效果观察[J].山东医药,2016(7):52-54.
[7]周应芳.子宫腺肌病药物治疗原则及注意事项[J].中国实用妇科与产科杂志, 2017, 33(2):157-160.
[8]姜艳萍,张青冬,王楚平,等.左炔诺孕酮宫内缓释系统与小剂量米非司酮在子宫腺肌病治疗中的疗效比较研究[J].中国全科医学, 2017, 20(s1):111-113.
[9]毛力旦·买买提江,古孜娜·赛尔山别克.腹腔镜子宫楔形切除术联合术后使用曼月乐(阴道置放)治疗子宫腺肌病效果观察[J].实用妇科内分泌杂志:电子版, 2016, 3(18):143.
[10]李桂春.温经祛瘀汤治疗寒凝血阻型月经不调患者的临床疗效及其生活质量的影响[J].中国民康医学,2016,28(19):53-55.
[11]曹芸.散结镇痛胶囊对子宫内膜异位症及子宫腺肌病痛经治疗效果观察[J].首都食品与医药,2017,24(12):79-80.
[12]宋亚丽.行气祛瘀汤在子宫腺肌病患者治疗中的临床效果[J].海峡药学,2017, 29(6):149-150.
[2]蔡婷.子宫动脉栓塞术联合行气祛瘀汤在弥漫型子宫腺肌病的应用研究[J].中国预防医学杂志, 2017(2):156-158.
[3]胡李萍.祛瘀消异汤用于子宫腺肌病治疗中的临床效果[J].内蒙古中医药, 2016, 35(14):3-4.
[4]李娟,张小妹,王丹.补肾祛瘀、行气止痛结合穴位烫熨治疗痛经的临床研究[J].光明中医, 2017, 32(17):2449-2451.
[5]高世荣.探析温经祛瘀汤用于寒凝血阻型月经不调治疗中的效果[J].中西医结合心血管病电子杂志, 2017, 5(27):147-148.
[6]赵蓉,顾玉婵,王丽梅,等.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病效果观察[J].山东医药,2016(7):52-54.
[7]周应芳.子宫腺肌病药物治疗原则及注意事项[J].中国实用妇科与产科杂志, 2017, 33(2):157-160.
[8]姜艳萍,张青冬,王楚平,等.左炔诺孕酮宫内缓释系统与小剂量米非司酮在子宫腺肌病治疗中的疗效比较研究[J].中国全科医学, 2017, 20(s1):111-113.
[9]毛力旦·买买提江,古孜娜·赛尔山别克.腹腔镜子宫楔形切除术联合术后使用曼月乐(阴道置放)治疗子宫腺肌病效果观察[J].实用妇科内分泌杂志:电子版, 2016, 3(18):143.
[10]李桂春.温经祛瘀汤治疗寒凝血阻型月经不调患者的临床疗效及其生活质量的影响[J].中国民康医学,2016,28(19):53-55.
[11]曹芸.散结镇痛胶囊对子宫内膜异位症及子宫腺肌病痛经治疗效果观察[J].首都食品与医药,2017,24(12):79-80.
[12]宋亚丽.行气祛瘀汤在子宫腺肌病患者治疗中的临床效果[J].海峡药学,2017, 29(6):149-150.