高频超声弹性成像与超声造影在甲状腺结节良恶性鉴别中的应用价值
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摘要
目的研究高频超声弹性成像与超声造影在甲状腺结节良恶性鉴别中的应用价值。方法选取我院2016年9月至2017年9月收治的甲状腺结节患者120例为研究对象,采用高频超声弹性成像、超声造影及其联合应用诊断甲状腺结节良恶性,比较不同检查方法的准确率。结果超声造影联合高频超声弹性成像检查的灵敏度、特异度、阳性预测值、阴性预测值及符合率均高于超声造影及高频超声弹性成像单独检查(P<0.05)。超声造影联合高频超声弹性成像检查的ROC曲线下面积大于超声造影及高频超声弹性成像单独检查(P<0.05)。结论高频超声弹性成像与超声造影技术对在鉴别甲状腺结节的良恶性方面均具有较高的诊断价值,两者联合检查可在一定程度上提高确诊率。
Objective To study the application value of high frequency ultrasound elastography and contrast-enhanced ultrasound in differentiation of benign and malignant thyroid nodules. Methods A total of 120 patients with thyroid nodules admitted in our hospital from September 2016 to September 2017 were selected as the research objects, high frequency ultrasound elastography, contrast-enhanced ultrasound and the combination of the two methods were used to diagnose benign and malignant thyroid nodules. Accuracy of different methods were compared. Results The sensitivity, specificity, positive predictive value, negative predictive value and coincidence rate of contrast-enhanced ultrasound combined with high-frequency ultrasound elastography were higher than those of contrast-enhanced ultrasound and high-frequency ultrasound elastography alone(P <0.05). The area under ROC curve of contrast-enhanced ultrasound combined with high-frequency ultrasound elastography was larger than that of contrast-enhanced ultrasound and high-frequency ultrasound elastography alone(P<0.05).Conclusion High-frequency ultrasound elastography and contrast-enhanced ultrasound have high diagnostic value in differentiation of benign and malignant thyroid nodules. The combined examination of the two techniques can improve the diagnostic accuracy to a certain extent.
Objective To study the application value of high frequency ultrasound elastography and contrast-enhanced ultrasound in differentiation of benign and malignant thyroid nodules. Methods A total of 120 patients with thyroid nodules admitted in our hospital from September 2016 to September 2017 were selected as the research objects, high frequency ultrasound elastography, contrast-enhanced ultrasound and the combination of the two methods were used to diagnose benign and malignant thyroid nodules. Accuracy of different methods were compared. Results The sensitivity, specificity, positive predictive value, negative predictive value and coincidence rate of contrast-enhanced ultrasound combined with high-frequency ultrasound elastography were higher than those of contrast-enhanced ultrasound and high-frequency ultrasound elastography alone(P <0.05). The area under ROC curve of contrast-enhanced ultrasound combined with high-frequency ultrasound elastography was larger than that of contrast-enhanced ultrasound and high-frequency ultrasound elastography alone(P<0.05).Conclusion High-frequency ultrasound elastography and contrast-enhanced ultrasound have high diagnostic value in differentiation of benign and malignant thyroid nodules. The combined examination of the two techniques can improve the diagnostic accuracy to a certain extent.
引文
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[9]刘景萍,张秀芳,胡健,等.高频超声、弹性成像联合超声造影在甲状腺结节诊断中应用价值[J].海南医学,2017,28(13):2143-2146.
[10]陈超男,钱林学,胡向东,等.常规超声及超声新技术诊断甲状腺结节的临床应用[J].中国医学装备,2016,13(12):41-44.
[2]刘欣,费翔,唐杰,等.甲状腺结节超声特征对甲状腺癌的诊断准确性分析[J].临床超声医学杂志,2016,18(2):124-126.
[3]顾继英,金利芳,姜露莹,等.超声实时弹性成像技术在甲状腺结节鉴别诊断中的价值[J].中华实用诊断与治疗杂志,2016,30(1):62-64.
[4]宋喜亮,魏海东,郑磊,等.甲状腺结节超声特点及其Logistic回归分析[J].中国地方病防治杂志,2018,33(1):53-54.
[5]郭俊敏,张志荣,许瑞霞.彩超在甲状腺结节性疾病诊断中的应用[J].临床医学研究与实践,2016,1(12):125-126.
[6]王鑫,李玲.B-flow超声显像、弹性成像及超声造影技术在甲状腺结节诊断中的应用[J].陕西医学杂志,2017,46(8):1068-1069.
[7]温钊,师红莉.高频超声弹性成像及超声造影对甲状腺良恶性结节的诊断分析[J].医学影像学杂志,2017,27(7):1388-1390.
[8]卢晓文,莫华,刘进阳.甲状腺彩超及数据系统(TI-RADS)在筛查及诊断甲状腺结节中的应用效果[J].临床医学研究与实践,2017,2(23):132-133.
[9]刘景萍,张秀芳,胡健,等.高频超声、弹性成像联合超声造影在甲状腺结节诊断中应用价值[J].海南医学,2017,28(13):2143-2146.
[10]陈超男,钱林学,胡向东,等.常规超声及超声新技术诊断甲状腺结节的临床应用[J].中国医学装备,2016,13(12):41-44.