五草清泉饮治疗急性肾盂肾炎的疗效分析
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摘要
目的观察五草清泉饮配合西药治疗急性肾盂肾炎的临床疗效及安全性并探讨其作用机制。方法患者114例随机分为两组,两组均给予基础治疗,观察组在对照组基础上配合五草清泉饮汤剂治疗。观察两组的临床症状总积分、主要临床症状积分、C反应蛋白(CRP)、降钙素原(PCT)及复发率。比较两组的临床疗效。结果观察组总有效率为94.34%,高于对照组的88.46%(P <0.05);治疗后两组主要临床症状总积分、主要临床症状(发热,腰酸腰痛,膀胱刺激症状)评分均低于治疗前(P <0.05),且观察组低于对照组(P <0.05)。治疗后两组CRP、PCT水平均低于治疗前(P <0.05),但组间差异无统计学意义(P> 0.05)。两组复发率比较,观察组低于对照组(P <0.05)。结论五草清泉饮配合西药治疗急性肾盂肾炎能明显提高治疗疗效,并降低复发率。
Objective: To observe the clinical efficacy and safety of Wucao Qingquan Decoction combined with Western medicine on acute pyelonephritis, and to explore its mechanism. Methods: 114 cases were randomly divided into the treatment group and the control group. The control group received routine treatment. The treatment group was treated with Wucao Qingquan Decoction on that basis. The total scores of clinical symptoms,main clinical symptoms,CRP,PCT and recurrence rate of the two groups were observed,and the clinical efficacy was compared. Results: The total effective rate of the treatment group was 94.34%, higher than that of the control group(88.46%)(P < 0.05). After treatment,the total scores of main clinical symptoms and the score of main clinical symptoms(fever,low back pain,bladder irritation) in the two groups were lower than those before treatment(P< 0.05),and the treatment group was lower than the control group(P < 0.05). After treatment,CRP and PCT were lower than those before treatment(P < 0.05). However,there was no significant difference between the groups(P >0.05). The recurrence rate of the treatment group was lower than that of the control group(P < 0.05). Conclusion:Wucao Qingquan Decoction combined with Western medicine on acute pyelonephritis can significantly improve the therapeutic effects.
Objective: To observe the clinical efficacy and safety of Wucao Qingquan Decoction combined with Western medicine on acute pyelonephritis, and to explore its mechanism. Methods: 114 cases were randomly divided into the treatment group and the control group. The control group received routine treatment. The treatment group was treated with Wucao Qingquan Decoction on that basis. The total scores of clinical symptoms,main clinical symptoms,CRP,PCT and recurrence rate of the two groups were observed,and the clinical efficacy was compared. Results: The total effective rate of the treatment group was 94.34%, higher than that of the control group(88.46%)(P < 0.05). After treatment,the total scores of main clinical symptoms and the score of main clinical symptoms(fever,low back pain,bladder irritation) in the two groups were lower than those before treatment(P< 0.05),and the treatment group was lower than the control group(P < 0.05). After treatment,CRP and PCT were lower than those before treatment(P < 0.05). However,there was no significant difference between the groups(P >0.05). The recurrence rate of the treatment group was lower than that of the control group(P < 0.05). Conclusion:Wucao Qingquan Decoction combined with Western medicine on acute pyelonephritis can significantly improve the therapeutic effects.
引文
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[15]俞秋云,陈燕,唐铖,等.朱佳运用加味玉屏风散治疗感染后咳嗽经验[J].湖南中医杂志,2018,34(10):21-23.
[16]何庆东.玉屏风散联合激素治疗小儿肾病疗效观察[J].心电图杂志:电子版,2018,7(3):119-120.
[2]陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:2341.
[3]国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:42-43.
[4]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:156-172.
[5]秦绍久.左氧氟沙星联合三金片治疗急性肾盂肾炎的效果分析[J].当代医药论丛,2017,15(2):117-119.
[6]齐作战,杨锋,金志.中西医结合治疗急性肾盂肾炎膀胱湿热证临床观察[J].新中医,2017,49(12):61-63.
[7]杨蕾.健脾益肾清热利湿方辅助治疗急性肾盂肾炎的疗效观察[J].湖南中医药大学学报,2016,36(12):52-54.
[8]涂珗.急性肾盂肾炎的中医药治疗[J].长春中医药大学学报,2011,27(3):400-401.
[9]张汉明.中西医结合治疗急性肾盂肾炎的临床效果分析[J]中国处方药,2016,14(9):92-93.
[10]邓巍.中西医结合治疗急性肾盂肾炎30例观察[J].实用中医药杂志,2016,32(4):354.
[11]罗宏.中医治疗尿路感染的研究进展[J].辽宁中医药大学学报,2010,12(3):94-95.
[12]苏婷婷,傅春升,张学顺.活血化瘀药对临床抗菌药治疗效果的系统评价及临床用药分析[J].辽宁中医杂志,2016,43(11):2339-2340.
[13]李利荣.王春生辨治咳嗽经验[J].北京中医药,2015,34(7):547-548.
[14]丁元庆.《兰室秘藏》应用知母黄柏之浅识[J].中医函授通讯,1995,15(2):14-15.
[15]俞秋云,陈燕,唐铖,等.朱佳运用加味玉屏风散治疗感染后咳嗽经验[J].湖南中医杂志,2018,34(10):21-23.
[16]何庆东.玉屏风散联合激素治疗小儿肾病疗效观察[J].心电图杂志:电子版,2018,7(3):119-120.