闹羊花中的两个新化合物(英文)
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摘要
目的:研究中药闹羊花中的化学成分。方法:运用多种色谱方法进行分离和纯化,采用IR,UV,MS和1D,2D NMR技术进行结构解析。结果:从乙醇提取物中分得2个化合物,推定其结构分别为2α,10α-环氧-3β,5β,6β,14β,16β-五羟基-木藜烷和2,6-二羟基苯甲酸苯甲酯-6-O-α-L-鼠李糖基-(1 3)-β-D-葡萄糖苷。结论:两个化合物均为新化合物。
AIM: To study the chemical constituents of the flowers of Rhododendron molle.METHODS: Compounds were isolated by repeated chromatography over silica gel and Sephadex LH-20.Structures were elucidated based on spectral techniques,mainly 1D-and 2D-NMR and mass spectrometric analyses.RESULTS: Two compounds(1 and 2) were isolated.CONCLUSIONS: Compounds 1 and 2 were identified as two new compounds: 2α,10α-epoxy-3β,5β,6β,14β,16α-hexahydroxy-grayanane and benzyl 2,6-dihydroxybenzoate-6-O-α-L-rhamnopyranosyl-(1 3)-β-D-glucopyranoside,respectively.
AIM: To study the chemical constituents of the flowers of Rhododendron molle.METHODS: Compounds were isolated by repeated chromatography over silica gel and Sephadex LH-20.Structures were elucidated based on spectral techniques,mainly 1D-and 2D-NMR and mass spectrometric analyses.RESULTS: Two compounds(1 and 2) were isolated.CONCLUSIONS: Compounds 1 and 2 were identified as two new compounds: 2α,10α-epoxy-3β,5β,6β,14β,16α-hexahydroxy-grayanane and benzyl 2,6-dihydroxybenzoate-6-O-α-L-rhamnopyranosyl-(1 3)-β-D-glucopyranoside,respectively.
引文
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[3]Bao GH,Wang LQ,Qin GW,et al.One new diterpene glucoside from the roots of Rhododendron molle[J].Chin Chem Lett,2002,13(3):955-956.
[4]Bao GH,Wang LQ,Qin GW,et al.Diterpenoid and phenolic glycosides from the roots of Rhododendron molle[J].Planta Medica,2003,69:434-439.
[5]Li CJ,Liu H,Qin GW,et al.Diterpenoids from the fruits of Rhododendron molle[J].Acta Chim Sin,2003,61(7):1153-1156.
[6]Chen SN,Zhang HP,Qin GW,et al.Diterpenoids from the flowers of Rhododendron molle[J].J Nat Prod,2004,67:1903-1906.
[2]Li CJ,Wang LQ,Qin GW,et al.Diterpenoids from the fruits of Rhododendron molle[J].J Nat Prod,2000,63(9):1214-1217.
[3]Bao GH,Wang LQ,Qin GW,et al.One new diterpene glucoside from the roots of Rhododendron molle[J].Chin Chem Lett,2002,13(3):955-956.
[4]Bao GH,Wang LQ,Qin GW,et al.Diterpenoid and phenolic glycosides from the roots of Rhododendron molle[J].Planta Medica,2003,69:434-439.
[5]Li CJ,Liu H,Qin GW,et al.Diterpenoids from the fruits of Rhododendron molle[J].Acta Chim Sin,2003,61(7):1153-1156.
[6]Chen SN,Zhang HP,Qin GW,et al.Diterpenoids from the flowers of Rhododendron molle[J].J Nat Prod,2004,67:1903-1906.