鳞状细胞癌抗原在口腔鳞癌诊治中的应用
摘要
<正>口腔癌是世界上第6位常见的肿瘤,约90%的口腔和口咽恶性肿瘤是发生于衬里黏膜上皮的口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC),常发生于下唇、口底、腭、舌或扁桃体等部位,约占全身恶性肿瘤的1%~3%~([1])。近年来,口腔癌的发病率呈增加的趋势,多呈现年轻化~([2])。OSCC具有较强的局部浸润性,易出现颈部淋巴结转移、较
引文
1 汤晓飞,刘晓勇,吴洪儒,等.早期口腔癌诊断.中国实用口腔科杂志,2010,3(12):708-712.
2 徐佳瑛,杨丽丽,马超,等.IL-17、COX-2在口腔扁平苔藓和口腔鳞癌中的表达分析.实用癌症杂志,2013,28(5):480-482.
3 Czerninski R,Basile JR,Kartin-Gabay T,et al.Cytokines and tumor markers in potentially malignant disorders and oral squamous cell carcinoma:a pilot study.Oral Diseases,2014,20:477-481.
4 孙红梅,陈文彰,燕丽香,等.4种肿瘤标志物在肺癌病理分型、分期中的临床价值.现代肿瘤医学,2014,22(9):2105-2109.
5 I-How Chen,Chun-Ta Liao,Hung-Ming Wang,et al.Using SCC antigen and CRP levels as prognostic biomarkers in recurrent oral cavity squamous cell carcinoma.PLo S ONE,2014,9(7):e103265.
6 Ryusuke I,Yukinori T,Toshimichi Y,et al.Prognostic significance of serum squamous cell carcinoma antigen in patients with head and neck cancer.Acta Oto-Laryngologica,2015,135:295-301.
7 Shiang-Fu Huang,Fu-Chan Wei,Chun-Ta Liao,et al.Risk stratification in oral cavity squamous cell carcinoma by preoperative CRP and SCC antigen levels.Ann Surg Oncol,2012,19:3856-3864.
8 Martina Montagnana,Elisa Danese,Giuseppe Lippi,et al.Squamous cell carcinoma antigen in hepatocellular carcinoma:Ready for the prime time?Clinica Chimica Acta,2015,445:161-166.
9 Stenman J,Hedstrm J,Grénman R,et al.Relative levels of SCCA2 and SCCA1 m RNA in primary tumors predicts recurrent disease in squamous cell cancer of the head and neck.Int J Cancer,2001,95:39-43.
10 Deng Z,Hasegawa M,Yamashita Y,et al.Prognostic value of human papillomavirus and squamous cell carcinoma antigen in head and neck squamous cell carcinoma.Cancer Sci,2012,103:2127-2134.
11 Shimura K,Mabuchi S,Yokoi T,et al.Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice.J Gynecol Oncol,2013,24(4):321-329.
12 周扬,高静,贾兴旺,等.鳞癌相关抗原在鳞癌及相关良性疾病中的临床意义.标记免疫分析与临床,2010,17(3):137-140.
13 李海如,郑健,吴蕾,等.血清SCC-Ag的变化对口腔鳞状细胞癌患者预后的影响.口腔医学,2015,34(5):350-352.
14 Yin Q,Wang Y,Zheng C,et al.Effects of two genes coding squamous cell carcinoma antigen on the diagnosis and treatment of cervical squamous cell carcinoma.Pak J Med Sci,2014,30(2):282-286.
15 田峰,齐素文,等.基于磁颗粒化学发光免疫分析方法检测鳞状细胞癌抗原.国际检验医学杂志,2015,36(13):1823-1825.
16 Barak V,Meirovitz A,Leibovici V,et al.The diagnostic and prognostic value of tumor markers(CEA,SCC,CYFRA 21-1,TPS)in head and neck cancer patients.Anticancer Res,2015,35(10):5519-5524.
17 Banal A,Haceneb K,Berthelot-Ruffc E,et al.Comparison of cyfra 21-1 and SCC assays in head and neck tumours.Tumor Biology,2001,22:27-35.
18 Imai R,Takenaka Y,Yasui T,et al.Prognostic significance of serum squamous cell carcinoma antigen in patients with head and neck cancer.Acta Otolaryngol,2015,135(3):295-301.
19 戴捷,金强,刘刚,等.鳞状细胞癌相关抗原研究进展.淮海医学,2012,30(2):188-190.
20 Wei-Hung Lin,I-How Chen,Fu-Chan Wei,et al.Clinical significance of preoperative squamous cell carcinoma antigen in oral-cavity squamous cell carcinoma.Laryngoscope,2011,121:971-977.
21 汪维健,匡威,李洪涛,等.缓释型氟尿嘧啶局部植入治疗口腔癌的初步研究.中国现代药物应用,2012,6(6):11-13.
22 常哲兴,高云东,张雪峰,等.肺癌患者化疗前后CEA、NSE、SCC-Ag和CYFRA21-1的表达及意义.中国实验诊断学,2014,18(11):1813-1816.
23 马瑞兰,张海琛,邹丽娟,等.中晚期子宫颈鳞癌患者同步放化疗的疗效及远处转移的影响因素分析.中华妇产科杂志,2015,50(2):125-130.
24 邓湘,修霞,王德昌,等.CYFRA 21-1肿瘤标志物在宫颈鳞癌诊断和放疗疗效评价中的作用.中国临床保健杂志,2007,10(3):249-251.
25 陈文娟,潘建基,江楠,等.鳞状细胞相关抗原在宫颈癌同步放化疗中的表达及意义.中国医药指南,2013年,11(22):26-28.
26 刘阳晨,高飞,周绍兵,等.联合检测食管鳞癌放疗前后血清SCC,VEGF、CYFRA21-1的临床意义.现代肿瘤医学,2012,20(6):1194-1196.
27 Micke O,Bruns F,Schafer U,et al.The impact of squamous cell carcinoma(SCC)antigen in patients with advanced cancer of uterine cervix treated with chemo-radiotherapy.Anticancer Res,2005,25(3A):1663-1666.
28 Kandiloros D,Eleftheriadou A,Chalastras T,et al.Prospective study of a panel of tumor markers as prognostic factors in patients with squamous cell carcinoma of head and neck.Medical Oncology,2006,23(4):463-470.
29 Xiao-yu Feng,Jian-hua Li,Jin-zhong Li,et al.Serum SCCA,cyfra 21-1,EGFR and cyclin D1 levels in patients with oral squamous cell carcinoma.Int J Biol Markers,2010,25(2):93-98.
2 徐佳瑛,杨丽丽,马超,等.IL-17、COX-2在口腔扁平苔藓和口腔鳞癌中的表达分析.实用癌症杂志,2013,28(5):480-482.
3 Czerninski R,Basile JR,Kartin-Gabay T,et al.Cytokines and tumor markers in potentially malignant disorders and oral squamous cell carcinoma:a pilot study.Oral Diseases,2014,20:477-481.
4 孙红梅,陈文彰,燕丽香,等.4种肿瘤标志物在肺癌病理分型、分期中的临床价值.现代肿瘤医学,2014,22(9):2105-2109.
5 I-How Chen,Chun-Ta Liao,Hung-Ming Wang,et al.Using SCC antigen and CRP levels as prognostic biomarkers in recurrent oral cavity squamous cell carcinoma.PLo S ONE,2014,9(7):e103265.
6 Ryusuke I,Yukinori T,Toshimichi Y,et al.Prognostic significance of serum squamous cell carcinoma antigen in patients with head and neck cancer.Acta Oto-Laryngologica,2015,135:295-301.
7 Shiang-Fu Huang,Fu-Chan Wei,Chun-Ta Liao,et al.Risk stratification in oral cavity squamous cell carcinoma by preoperative CRP and SCC antigen levels.Ann Surg Oncol,2012,19:3856-3864.
8 Martina Montagnana,Elisa Danese,Giuseppe Lippi,et al.Squamous cell carcinoma antigen in hepatocellular carcinoma:Ready for the prime time?Clinica Chimica Acta,2015,445:161-166.
9 Stenman J,Hedstrm J,Grénman R,et al.Relative levels of SCCA2 and SCCA1 m RNA in primary tumors predicts recurrent disease in squamous cell cancer of the head and neck.Int J Cancer,2001,95:39-43.
10 Deng Z,Hasegawa M,Yamashita Y,et al.Prognostic value of human papillomavirus and squamous cell carcinoma antigen in head and neck squamous cell carcinoma.Cancer Sci,2012,103:2127-2134.
11 Shimura K,Mabuchi S,Yokoi T,et al.Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice.J Gynecol Oncol,2013,24(4):321-329.
12 周扬,高静,贾兴旺,等.鳞癌相关抗原在鳞癌及相关良性疾病中的临床意义.标记免疫分析与临床,2010,17(3):137-140.
13 李海如,郑健,吴蕾,等.血清SCC-Ag的变化对口腔鳞状细胞癌患者预后的影响.口腔医学,2015,34(5):350-352.
14 Yin Q,Wang Y,Zheng C,et al.Effects of two genes coding squamous cell carcinoma antigen on the diagnosis and treatment of cervical squamous cell carcinoma.Pak J Med Sci,2014,30(2):282-286.
15 田峰,齐素文,等.基于磁颗粒化学发光免疫分析方法检测鳞状细胞癌抗原.国际检验医学杂志,2015,36(13):1823-1825.
16 Barak V,Meirovitz A,Leibovici V,et al.The diagnostic and prognostic value of tumor markers(CEA,SCC,CYFRA 21-1,TPS)in head and neck cancer patients.Anticancer Res,2015,35(10):5519-5524.
17 Banal A,Haceneb K,Berthelot-Ruffc E,et al.Comparison of cyfra 21-1 and SCC assays in head and neck tumours.Tumor Biology,2001,22:27-35.
18 Imai R,Takenaka Y,Yasui T,et al.Prognostic significance of serum squamous cell carcinoma antigen in patients with head and neck cancer.Acta Otolaryngol,2015,135(3):295-301.
19 戴捷,金强,刘刚,等.鳞状细胞癌相关抗原研究进展.淮海医学,2012,30(2):188-190.
20 Wei-Hung Lin,I-How Chen,Fu-Chan Wei,et al.Clinical significance of preoperative squamous cell carcinoma antigen in oral-cavity squamous cell carcinoma.Laryngoscope,2011,121:971-977.
21 汪维健,匡威,李洪涛,等.缓释型氟尿嘧啶局部植入治疗口腔癌的初步研究.中国现代药物应用,2012,6(6):11-13.
22 常哲兴,高云东,张雪峰,等.肺癌患者化疗前后CEA、NSE、SCC-Ag和CYFRA21-1的表达及意义.中国实验诊断学,2014,18(11):1813-1816.
23 马瑞兰,张海琛,邹丽娟,等.中晚期子宫颈鳞癌患者同步放化疗的疗效及远处转移的影响因素分析.中华妇产科杂志,2015,50(2):125-130.
24 邓湘,修霞,王德昌,等.CYFRA 21-1肿瘤标志物在宫颈鳞癌诊断和放疗疗效评价中的作用.中国临床保健杂志,2007,10(3):249-251.
25 陈文娟,潘建基,江楠,等.鳞状细胞相关抗原在宫颈癌同步放化疗中的表达及意义.中国医药指南,2013年,11(22):26-28.
26 刘阳晨,高飞,周绍兵,等.联合检测食管鳞癌放疗前后血清SCC,VEGF、CYFRA21-1的临床意义.现代肿瘤医学,2012,20(6):1194-1196.
27 Micke O,Bruns F,Schafer U,et al.The impact of squamous cell carcinoma(SCC)antigen in patients with advanced cancer of uterine cervix treated with chemo-radiotherapy.Anticancer Res,2005,25(3A):1663-1666.
28 Kandiloros D,Eleftheriadou A,Chalastras T,et al.Prospective study of a panel of tumor markers as prognostic factors in patients with squamous cell carcinoma of head and neck.Medical Oncology,2006,23(4):463-470.
29 Xiao-yu Feng,Jian-hua Li,Jin-zhong Li,et al.Serum SCCA,cyfra 21-1,EGFR and cyclin D1 levels in patients with oral squamous cell carcinoma.Int J Biol Markers,2010,25(2):93-98.