蔓越莓的文献研究及其中药性能探讨
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摘要
目的:分析外来植物药蔓越莓研究文献,依据中医药理论探讨蔓越莓的中药药性,为蔓越莓与中药配伍的临床合理使用及产品开发提供理论依据。方法:选取Web of Science(Wo S)及pubmed数据库中外来药物蔓越莓的相关英文文献,对196篇临床实验,140篇活性成分文献进行研究与分析,并结合中医理论对蔓越莓的中药药性进行初步探讨。结果:蔓越莓的中药药性为性味归经为酸、甘,凉;归肾、膀胱、脾经。功效主治为清热通淋,化脂降浊,健脾益气。用于湿热淋证,高脂血症,脾气虚弱,倦怠无力。结论:概括归纳蔓越莓的性味归经、功效主治及用法用量,赋予其中药药性,使其成为新"外来中药",可以为蔓越莓与中药的配伍及临床应用提供理论依据,能更好地在医疗保健行业中推广应用,研发新产品。
Objective: Based on the analysis of foreign plant medicine cranberry science research literature,to further explore the Chinese medicine properties of cranberry,providing a theoretical basis for clinical use and product development of cranberry with Traditional Chinese Medicine( TCM). Methods: By searching English literature of cranberry in the Web of Science( WoS) and PubM ed database,a total of 196 articles of clinical experiments and 140 articles of active components were studied and analyzed.Combining Traditional Chinese Medicine theory,the Chinese medicine properties of cranberry were discussed. Results: The Chinese medicine property of cranberry is cool,with sour and sweet flavor. Its channel tropisms are kidney,bladder and spleen. The major functions of cranberry are clearing heat and freeing strangury,lipid lowering and turbidity reduction,strengthening the spleen and replenishing qi. Therefore,cranberry is suitable for treating damp-heat stranguria,hyperlipemia,deficiency of spleen qi,lassitude and asthenia. Conclusion: By summarizing the property and flavor,channel tropism,major functions,dosage and administration of cranberry,this paper provided the Chinese medicine properties of cranberry,which makes it become a new"foreign Chinese medicine". This provides a theoretical basis for the compatibility of cranberry and Traditional Chinese Medicine,and clinical application,to better promote the application of cranberry in the healthcare and product development.
Objective: Based on the analysis of foreign plant medicine cranberry science research literature,to further explore the Chinese medicine properties of cranberry,providing a theoretical basis for clinical use and product development of cranberry with Traditional Chinese Medicine( TCM). Methods: By searching English literature of cranberry in the Web of Science( WoS) and PubM ed database,a total of 196 articles of clinical experiments and 140 articles of active components were studied and analyzed.Combining Traditional Chinese Medicine theory,the Chinese medicine properties of cranberry were discussed. Results: The Chinese medicine property of cranberry is cool,with sour and sweet flavor. Its channel tropisms are kidney,bladder and spleen. The major functions of cranberry are clearing heat and freeing strangury,lipid lowering and turbidity reduction,strengthening the spleen and replenishing qi. Therefore,cranberry is suitable for treating damp-heat stranguria,hyperlipemia,deficiency of spleen qi,lassitude and asthenia. Conclusion: By summarizing the property and flavor,channel tropism,major functions,dosage and administration of cranberry,this paper provided the Chinese medicine properties of cranberry,which makes it become a new"foreign Chinese medicine". This provides a theoretical basis for the compatibility of cranberry and Traditional Chinese Medicine,and clinical application,to better promote the application of cranberry in the healthcare and product development.
引文
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[3]Gunther S,Patterson RE,Kristal AR,et al.Demographic and healthrelated correlates of herbal and specialty supplement use[J].J Am Diet Assoc,2004,104(1):27-34.
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[5]张建军,陈绍红,朱映黎,等.南美草药阿萨伊的中药性能与功用探析[J].中国中药杂志,2015,40(11):2258-2264.
[6]张建军,王淳,费文婷,等.外来药物“中药化”的研究思路与策略[J].中华中医药杂志,2017,32(4):1425-1430.
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[8]王梓贞.我国蔓越橘产业发展现状和展望[J].河北果树,2014,26(5):1,6.
[9]杨静慧,李建科,杨恩芹,等.蔓越莓栽培历史、现状及发展趋势[J].天津农学院学报,2009,16(3):44-46.
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[12]姚立君,李赫宇,李许伟,等.蔓越莓营养与保健功能研究进展[J].食品研究与开发,2013,34(8):120-123.
[13]Foxman B,Cronenwett AE,Spino C,et al.Cranberry juice capsules and urinary tract infection after surgery:results of a randomized trial[J].Am J Obstet Gynecol,2015,213(2):194.e1-8.
[14]Lee IT,Chan YC,Lin CW,et al.Effect of cranberry extracts on lipid profiles in subjects with Type 2 diabetes[J].Diabet Med,2008,25(12):1473-1477.
[15]Nantz MP,Rowe CA,Muller C,et al.Consumption of cranberry polyphenols enhances humanγδ-T cell proliferation and reduces the number of symptoms associated with colds and influenza:a randomized,placebo-controlled intervention study[J].Nutr J,2013,12:161.
[16]Villarreal A,Stoecker BJ,Garcia C,et al.Cranberry juice improved antioxidant status without affecting bone quality in orchidectomized male rats[J].Phytomedicine,2007,14(12):815-820.
[17]毛光明,陈江,夏勇,等.蔓越莓对衰老小鼠和辐照小鼠抗氧化功能的影响[J].浙江预防医学,2007,19(5):10-12.
[18]Vostalova J,Vidlar A,Simanek V,et al.Are High Proanthocyanidins Key to Cranberry Efficacy in the Prevention of Recurrent Urinary Tract Infection?[J].Phytother Res,2015,29(10):1559-1567.
[19]Student V,Vidlar A,Bouchal J,et al.Cranberry intervention in patients with prostate cancer prior to radical prostatectomy.Clinical,pathological and laboratory findings[J].Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub,2016,160(4):559-565.
[20]Skarpańska-Stejnborn A,Basta P,Trzeciak J,et al.Effects of cranberry(Vaccinum macrocarpon)supplementation on iron status and inflammatory markers in rowers[J].J Int Soc Sports Nutr,2017,14:7.
[21]毛光明,陈玉满,鹿伟,等.蔓越莓对免疫系统的影响及胃黏膜保护作用的研究[J].中国卫生检验杂志,2007,17(12):2179-2181.
[22]王淳,张建军,王佳,等.玛咖的临床文献研究及其中药性能探讨[J].中华中医药杂志,2017,32(12):5569-5573.
[2]魏燕,詹子逸,章宇.蔓越莓生物活性物质及主要生理功能研究进展[J].食品研究与开发,2017,38(10):219-224.
[3]Gunther S,Patterson RE,Kristal AR,et al.Demographic and healthrelated correlates of herbal and specialty supplement use[J].J Am Diet Assoc,2004,104(1):27-34.
[4]邹宇,胡文忠,姜爱丽,等.蔓越橘中生物活性物质及其功能特性研究进展[J].食品工业科技,2013,34(19):396-399.
[5]张建军,陈绍红,朱映黎,等.南美草药阿萨伊的中药性能与功用探析[J].中国中药杂志,2015,40(11):2258-2264.
[6]张建军,王淳,费文婷,等.外来药物“中药化”的研究思路与策略[J].中华中医药杂志,2017,32(4):1425-1430.
[7]郭佳,丁庆波.蔓越莓的营养与功能特性概述[J].农产品加工(学刊),2011,28(5):100-104.
[8]王梓贞.我国蔓越橘产业发展现状和展望[J].河北果树,2014,26(5):1,6.
[9]杨静慧,李建科,杨恩芹,等.蔓越莓栽培历史、现状及发展趋势[J].天津农学院学报,2009,16(3):44-46.
[10]姜晶,吴林.4个蔓越桔品种引种表现初报[J].中国果树,2006,18(4):28-30,图版2.
[11]尹喜玲,段雪英,肖颖.蔓越莓的营养与保健作用[J].中国食物与营养,2003,9(7):42-43.
[12]姚立君,李赫宇,李许伟,等.蔓越莓营养与保健功能研究进展[J].食品研究与开发,2013,34(8):120-123.
[13]Foxman B,Cronenwett AE,Spino C,et al.Cranberry juice capsules and urinary tract infection after surgery:results of a randomized trial[J].Am J Obstet Gynecol,2015,213(2):194.e1-8.
[14]Lee IT,Chan YC,Lin CW,et al.Effect of cranberry extracts on lipid profiles in subjects with Type 2 diabetes[J].Diabet Med,2008,25(12):1473-1477.
[15]Nantz MP,Rowe CA,Muller C,et al.Consumption of cranberry polyphenols enhances humanγδ-T cell proliferation and reduces the number of symptoms associated with colds and influenza:a randomized,placebo-controlled intervention study[J].Nutr J,2013,12:161.
[16]Villarreal A,Stoecker BJ,Garcia C,et al.Cranberry juice improved antioxidant status without affecting bone quality in orchidectomized male rats[J].Phytomedicine,2007,14(12):815-820.
[17]毛光明,陈江,夏勇,等.蔓越莓对衰老小鼠和辐照小鼠抗氧化功能的影响[J].浙江预防医学,2007,19(5):10-12.
[18]Vostalova J,Vidlar A,Simanek V,et al.Are High Proanthocyanidins Key to Cranberry Efficacy in the Prevention of Recurrent Urinary Tract Infection?[J].Phytother Res,2015,29(10):1559-1567.
[19]Student V,Vidlar A,Bouchal J,et al.Cranberry intervention in patients with prostate cancer prior to radical prostatectomy.Clinical,pathological and laboratory findings[J].Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub,2016,160(4):559-565.
[20]Skarpańska-Stejnborn A,Basta P,Trzeciak J,et al.Effects of cranberry(Vaccinum macrocarpon)supplementation on iron status and inflammatory markers in rowers[J].J Int Soc Sports Nutr,2017,14:7.
[21]毛光明,陈玉满,鹿伟,等.蔓越莓对免疫系统的影响及胃黏膜保护作用的研究[J].中国卫生检验杂志,2007,17(12):2179-2181.
[22]王淳,张建军,王佳,等.玛咖的临床文献研究及其中药性能探讨[J].中华中医药杂志,2017,32(12):5569-5573.