摘要
目的调查预防性人乳头瘤病毒(human papillomavirus, HPV)疫苗在中国大陆上市后,四川省某农村地区女性对HPV及其预防性疫苗的认知情况及接种意愿,为今后在农村地区推广接种疫苗提供参考意见。方法整群非随机抽样的方法选择四川省某县农村地区女性作为调查人群。采用采用自行设计的《人乳头瘤病毒(HPV)疫苗认知情况调查表》收集一般人口学特征、HPV及HPV疫苗的认知情况、接种HPV疫苗的态度及影响接种的因素等信息。采用多因素logistic回归分析影响HPV接种意愿的影响因素。结果共调查1 273名农村女性,15.2%的调查对象在本次调查前听说过HPV,19.7%知道HPV疫苗在我国上市,1 139名(89.5%)调查对象愿意接种HPV疫苗。logistic回归分析发现,知晓HPV、知晓HPV对健康的危害很大、HPV疫苗已经在我国上市、接种过其他疫苗可能会促进HPV疫苗的接种(P<0.05)。医生或护士的推荐及医院的健康教育促进调查对象的接种意愿;国家负担全部或者负担部分费用是调查对象认为最主要的付费途径。结论四川省某地区农村女性HPV/HPV疫苗的认知水平低,但对疫苗接种持积极态度。加大合理有效的宣传教育力度将有利于今后HPV疫苗在农村地区的推广。
Objective To investigate the awareness and attitudes towards human papillomavirus(HPV) and its vaccines among female in a rural area in Sichuan Province after the commercial licensing of HPV prophylactic vaccines, in order to provide policy makers with suggestions on how to promote the application of HPV vaccines in rural area in future. Methods Nonrandom Clustering sampling was conducted to recruit the rural women. A questionnaire designed by ourselves was used to collect demographic information, knowledge of HPV and attitudes towards HPV vaccines and some suggestions. Logistic regression was used to find factors influenced the willingness to accept HPV vaccination. Results A total of 1 273 rural participants were included. 15.2% women heard of HPV, while 19.7% knew HPV vaccines on market in China. 1 139(89.5%)women had positive attitude towards HPV vaccination. The results of Logistic regression showed that heard of HPV, knowing HPV vaccines already on market, harm of HPV for health, having other vaccines before could improve willingness to HPV vaccines(P<0.05). Recommendation by doctors or nurses and health education in hospitals promoted the vaccination willingness of the respondents. The state bearing all or part of the cost is considered by the respondents as the most important payment channel. Conclusion The awareness of HPV and HPV vaccines of rural women in Sichuan province is low, but acceptance towards HPV vaccine is high. More effective educational intervention and publicity of HPV related diseases and HPV vaccines are critically necessary.
引文
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