丙泊酚复合七氟烷对小儿麻醉苏醒期躁动的疗效研究
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摘要
目的:研究丙泊酚复合七氟烷对小儿麻醉苏醒期躁动的临床有效性。方法:本次研究病例均选取2017年1-12月在笔者所在医院行手术治疗的患儿,共70例;根据不同麻醉方法分为A组(施予丙泊酚)、B组(施予七氟烷)、C组(施予丙泊酚复合七氟烷),对比三组麻醉效果及其麻醉苏醒期躁动发生情况。结果:三组平均手术时间、麻醉清醒时间对比差异无统计学的意义(P>0.05);C组躁动发生率(8.33%)明显低于A组、B组,差异有统计学意义(P<0.05);且C组躁动评分为(1.29±0.47)分,明显低于A组、B组,差异有统计学意义(P<0.05);三组不良反应发生率比较差异无统计学意义(P>0.05)。结论:丙泊酚复合七氟烷能够进一步降低小儿麻醉苏醒期躁动,具有较高的临床应用价值。
Objective:To study the clinical efficacy of Propofol combined with Sevoflurane in restlessness during anesthesia recovery in children. Method:All the cases in this study were selected from January to December 2017 in the author's hospital for surgical treatment,a total of 70 cases.According to different anesthetic methods,group A was divided into two groups:group A(treated with Propofol),group B(treated with Sevoflurane),group C(treated with Propofol combined with Sevoflurane).The anaesthesia effect and restlessness during anaesthesia were compared among the three groups.Result:There was no significant difference among the three groups in the average operation time and the time of anesthetic consciousness(P>0.05).The incidence of restlessness in group C was 8.33%,significantly lower than that of group A and B(P<0.05),and the restlessness score of group C was significantly lower than that of group A and group B(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:Propofol combined with Sevoflurane can further reduce the agitation in the recovery period of pediatric anesthesia,and has high clinical value.
Objective:To study the clinical efficacy of Propofol combined with Sevoflurane in restlessness during anesthesia recovery in children. Method:All the cases in this study were selected from January to December 2017 in the author's hospital for surgical treatment,a total of 70 cases.According to different anesthetic methods,group A was divided into two groups:group A(treated with Propofol),group B(treated with Sevoflurane),group C(treated with Propofol combined with Sevoflurane).The anaesthesia effect and restlessness during anaesthesia were compared among the three groups.Result:There was no significant difference among the three groups in the average operation time and the time of anesthetic consciousness(P>0.05).The incidence of restlessness in group C was 8.33%,significantly lower than that of group A and B(P<0.05),and the restlessness score of group C was significantly lower than that of group A and group B(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:Propofol combined with Sevoflurane can further reduce the agitation in the recovery period of pediatric anesthesia,and has high clinical value.
引文
[1]陈兰凤,张瑞东,朱邵军,等.瑞芬太尼复合丙泊酚或七氟烷对小儿扁桃体切除术术后躁动的影响[J].中国现代医生,2016,54(6):81-83,87.
[2]马媛,唐培佳.舒芬太尼+七氟烷在小儿经胸微创先心封堵术的麻醉效果观察[J].重庆医学,2016,45(15):2125-2127.
[3]刘雨梅,张奉超.七氟烷和复合丙泊酚在小儿气管异物取出术中的应用[J].中国医药导刊,2016,18(1):46-47.
[4]康定鑫,姬斌,李军,等.七氟烷和地氟烷对小儿手术中罗库溴铵持续输注速率的影响[J].中国临床药理学杂志,2017,33(21):2120-2123.
[5]王瑜,胡云霞,李祥奎,等.七氟烷吸入联合丙泊酚-瑞芬太尼复合静脉麻醉应用于小儿气管异物取出术的麻醉效果观察[J].实用医院临床杂志,2018,15(2):166-168.
[6]陈静霞.瑞芬太尼分别复合七氟烷和丙泊酚在小儿唇腭裂修复术麻醉中的效果对比[J].黑龙江医学,2018,42(4):314-315.
[7]薛利军,高彦东,张利佳,等.经喉罩七氟烷吸入麻醉复合腹股沟区域阻滞在小儿斜疝手术中的应用[J].中国基层医药,2016,23(19):2976-2980.
[8]吴华苗,张永年,徐小想,等.七氟烷复合舒芬太尼静脉麻醉在小儿腹腔镜疝气修复术中的应用[J].海南医学,2016,27(24):4097-4098,4099.
[9]符永强,徐彩萍.瑞芬太尼静脉输注联合丙泊酚靶控输注和七氟烷吸入麻醉在小儿短小手术中的效果[J].海峡药学,2017,29(12):127-129.
[10]艾宏.用七氟烷复合丙泊酚、芬太尼对行小儿气管异物取出术的患者实施麻醉的效果分析[J].当代医药论丛,2016,14(23):26-27.
[11]顾珍梅,李金玉,孙志楷,等.小儿七氟烷麻醉的苏醒期躁动与预防方式分析[J].吉林医学,2017,38(10):1813-1815.
[12]丁涛,曲月星,徐海霞,等.丙泊酚联合七氟烷复合麻醉对小儿麻醉苏醒期躁动评分的影响[J].现代生物医学进展,2016,16(26):5103-5105.
[13]冉隆青,伍孟军,刘怀清,等.右美托咪啶复合七氟烷麻醉辅助利多卡因超声雾化用于婴幼儿无痛纤支镜检查的安全性和有效性观察[J].中国临床医生杂志,2016,44(3):41-43.
[14]凤旭东,钟成跃,张杨,等.舒芬太尼联合七氟烷复合吸入麻醉在小儿腺样体肥大切除术中的应用效果评价[J].实用临床医药杂志,2018,22(3):90-92.
[15]谢宇宁.丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比[J].首都食品与医药,2017,24(6):36-37.
[2]马媛,唐培佳.舒芬太尼+七氟烷在小儿经胸微创先心封堵术的麻醉效果观察[J].重庆医学,2016,45(15):2125-2127.
[3]刘雨梅,张奉超.七氟烷和复合丙泊酚在小儿气管异物取出术中的应用[J].中国医药导刊,2016,18(1):46-47.
[4]康定鑫,姬斌,李军,等.七氟烷和地氟烷对小儿手术中罗库溴铵持续输注速率的影响[J].中国临床药理学杂志,2017,33(21):2120-2123.
[5]王瑜,胡云霞,李祥奎,等.七氟烷吸入联合丙泊酚-瑞芬太尼复合静脉麻醉应用于小儿气管异物取出术的麻醉效果观察[J].实用医院临床杂志,2018,15(2):166-168.
[6]陈静霞.瑞芬太尼分别复合七氟烷和丙泊酚在小儿唇腭裂修复术麻醉中的效果对比[J].黑龙江医学,2018,42(4):314-315.
[7]薛利军,高彦东,张利佳,等.经喉罩七氟烷吸入麻醉复合腹股沟区域阻滞在小儿斜疝手术中的应用[J].中国基层医药,2016,23(19):2976-2980.
[8]吴华苗,张永年,徐小想,等.七氟烷复合舒芬太尼静脉麻醉在小儿腹腔镜疝气修复术中的应用[J].海南医学,2016,27(24):4097-4098,4099.
[9]符永强,徐彩萍.瑞芬太尼静脉输注联合丙泊酚靶控输注和七氟烷吸入麻醉在小儿短小手术中的效果[J].海峡药学,2017,29(12):127-129.
[10]艾宏.用七氟烷复合丙泊酚、芬太尼对行小儿气管异物取出术的患者实施麻醉的效果分析[J].当代医药论丛,2016,14(23):26-27.
[11]顾珍梅,李金玉,孙志楷,等.小儿七氟烷麻醉的苏醒期躁动与预防方式分析[J].吉林医学,2017,38(10):1813-1815.
[12]丁涛,曲月星,徐海霞,等.丙泊酚联合七氟烷复合麻醉对小儿麻醉苏醒期躁动评分的影响[J].现代生物医学进展,2016,16(26):5103-5105.
[13]冉隆青,伍孟军,刘怀清,等.右美托咪啶复合七氟烷麻醉辅助利多卡因超声雾化用于婴幼儿无痛纤支镜检查的安全性和有效性观察[J].中国临床医生杂志,2016,44(3):41-43.
[14]凤旭东,钟成跃,张杨,等.舒芬太尼联合七氟烷复合吸入麻醉在小儿腺样体肥大切除术中的应用效果评价[J].实用临床医药杂志,2018,22(3):90-92.
[15]谢宇宁.丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比[J].首都食品与医药,2017,24(6):36-37.