光学相干断层扫描血管成像(OCTA)在眼科临床的应用进展
摘要
光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)是近几年来新兴的眼科影像学检查方法,OCTA具有无需造影剂、高分辨率、检查快捷、三维成像等优势,在视网膜静脉阻塞(retinal vein occlusion,RVO),糖尿病视网膜病变(diabetic retinopathy,DR),脉络膜新生血管(choroidal neovascularization,CNV),青光眼视神经损伤,眼前节等领域应用潜力巨大,但OCTA也有应用的局限性。本文对OCTA的成像原理及特点做简单介绍,就OCTA的临床应用进展做一综述。
引文
[1]Lei J,Durbin MK,Shi Y,et al.Repeatability and Reproducibility of Superficial Macular Retinal Vessel Density Measurements Using Optical Coherence Tomography Angiography En Face Images.JAMA Ophthalmol,2017,135:1092-1098.
[2]赵姝芝,李涛,郑冰清,等.糖尿病视网膜病变相关“代谢记忆”的研究进展.中华眼底病杂志,2013,29:103-106.
[3]Garcia JM,Lima TT,Louzada RN,et al.Diabet ic Macular Ischemia Diagnosis:Comparison between Optical Coherence Tomography Angiography and Fluorescein Angiography.J Ophthalmol,2016,2016:3989310.
[4]李慧,陈沁,喻晓兵,等.糖尿病视网膜病变黄斑区血流密度和黄斑中心凹无血管区面积的变化.中华糖尿病杂志,2017,9:435-439.
[5]向湘,马红婕,唐仕波,等.COTA在DR患者黄斑血流密度观察中的应用.国际眼科杂志,2017,17:1344-1347.
[6]刘青,艾明.光学相干断层扫描血管成像(OCTA)和荧光素血管造影(FFA)对比观察增生型糖尿病视网膜病变(PDR).眼科新进展,2017,37:52-55.
[7]Michalska-Malecka K,Heinke Knudsen A.Optical coherence tomography angiography in patients with diabetic retinopathy treated with anti-VEGF intravitreal injections:Case report J.Medicine(Baltimore),2017,96:e8379.
[8]曾苗,陈晓,宋艳萍,丁琴,陈中山.视网膜中央静脉阻塞患眼光相干断层扫描血管成像与荧光素眼底血管造影结果对比分析.中华眼底病杂志,2016,32:362-366.
[9]Samara WA,Shahlaee A,Sridhar J,et al.Quantitative Optical Coherence Tomography Angiography Features and Visual Function in Eyes With Branch Retinal Vein Occlusion.Am JOphthalmol,2016,166:76-83.
[10]孙晓丽,丛春霞,李立,等.光学相干断层扫描血管成像与传统多模式眼底成像对渗出型老年性黄斑变性脉络膜新生血管诊断与活动性判断的对比观察.中华眼底病杂志,2017,33:10-14.
[11]马楠,陈有信,巩迪,等.息肉样脉络膜血管病变吲哚青绿血管造影与光相干断层扫描血管成像图像特征对比观察.中华眼底病杂志,2015,31:421-424.
[12]Kim JY,Kwon OW,Oh HS,et al.Optical coherence tomographyangiography in patients with polypoidal choroidal vasculopathy.J.Graefes Arch Clin Exp Ophthalmol,2016,254:1505-1510.
[13]Takayama K,Ito Y,Kaneko H,et al.Comparison of indocyanine green angiography and optical coherence tomography angiography in polypoidal choroidal vasculopathy.J.Eye(Lond),2017,31:45-52.
[14]王敏.利用光相干断层扫描血管成像技术优势提升视网膜脉络膜血管疾病认知水平.中华眼底病杂志,2016,32:353-356.
[15]李倩,陈长征,苏钰,等.OCT血管成像术在病理性近视黄斑新生血管病变诊疗中的应用价值.中华实验眼科杂志,2016,34:1102-1106.
[16]莫宾,周海英,焦璇,等.中心性浆液性脉络膜视网膜病变的OCTA特点及与ICGA的比较分析.国际眼科杂志,2017,17:1351-1355.
[17]Corbelli E,Carnevali A,Marchese A,et al.Optical Coherence Tomography Angiography Features of Angioid Streaks.J,Retina,2017,0:1-9.
[18]Baumal CR,de Carlo TE,Waheed NK,et al.Sequential Optical Coherence Tomography Angiography for Diagnosis and Treatment of Choroidal Neovascularization in Multifocal Choroiditis.JAMA Ophthalmol,2015,133:1078-1090.
[19]Triolo G,Rabilol A,Shemonski ND,et al.Optical coherence tomagraphy angiography Macular and Peripapillary Vessel Perfusion Density in Healthy Subject,Glaucoma Suspects,and Glaucoma patients.J.Invest Ophthalmol Vis Sci,2017,58:5713-5722.
[20]Zhang S,Wu C,Liu L,et al.Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary AngleClosure Glaucoma.Am J Ophthalmol,2017,182:194-200.
[21]Zivkovic M,Dayanir V,Kocaturk T,et al.Foveal Avascular Zone in Normal Tension Glaucoma Measured by Optical Coherence Tomography Angiography.J.Biomed Res Int,2017,2017:3079141.
[22]朱佩文,邹雪香,刘康,等.成光学相干断层扫描血管造影(OCTA)在角膜厚度测量中的临床研究.眼科新进展,2017,37:732-735.
[23]ANG M,CAI Y,SHAHIPASAND S,SIM DA,KEANE PA,SNGCC,et al.En face optical coherence tomography angiography for corneal neovascularisation.Br JOphthalmol,2016,100:616-621.
[24]Chien JL,Sioufi K,Ferenczy S,et al.Optical Coherence Tomography Angiography Features of Iris Racemose Hemangioma in 4 Cases.JAMA Ophthalmol,2017,135:1106-1110.
[25]Marcus Ang,Anna C.S.Tan,Chui Ming Gemmy Cheung,et al.Opticla coherence tomography angiography:a review of current and future clinical applications.J.Graefe’s Arch Clin Exp Ophthalmol,2018,256:237-245.
[26]Akahori T,Iwase T,Yamamoto K,et al.Macular displacement after vitrectomy in eyes with idiopathic macular hole determined by optical coherence tomography angiography.Am J Ophthalmol,2018 Mar 2.pii:S0002-9394(18)30096-5.
[27]Lyu S,Zhang M,Wang RK,et al.Analysis of the characteristics of optical coherence tomography angiography for retinal cavernous hemangioma:A case report.J.Medicine(Baltimore),2018,97:e9940.
[28]Lee SY,Cheng JL,Gehrs KM,et al.Choroidal Features of Acute Macular Neuroretinopathy via Optical Coherence Tomography Angiography and Correlation with Serial Multimodal Imaging.JAMA Ophthalmol,2017,135:1177-1183.
[29]Lonngi M,Velez FG,Tsui I,et al.Spectral-Domain Optical Coherence Tomography Angiography in Children With Amblyopia.JAMA Ophthalmol,2017,135:1086-1091.
[30]Campbell JP,Nudleman E,Yang J,et al.Handheld Optical Coherence Tomography Angiography and Ultra-Wide-Field Optical Coherence Tomography in Retinopathy of Prematurity.JAMA Ophthalmol,2017,135:977-981.
[2]赵姝芝,李涛,郑冰清,等.糖尿病视网膜病变相关“代谢记忆”的研究进展.中华眼底病杂志,2013,29:103-106.
[3]Garcia JM,Lima TT,Louzada RN,et al.Diabet ic Macular Ischemia Diagnosis:Comparison between Optical Coherence Tomography Angiography and Fluorescein Angiography.J Ophthalmol,2016,2016:3989310.
[4]李慧,陈沁,喻晓兵,等.糖尿病视网膜病变黄斑区血流密度和黄斑中心凹无血管区面积的变化.中华糖尿病杂志,2017,9:435-439.
[5]向湘,马红婕,唐仕波,等.COTA在DR患者黄斑血流密度观察中的应用.国际眼科杂志,2017,17:1344-1347.
[6]刘青,艾明.光学相干断层扫描血管成像(OCTA)和荧光素血管造影(FFA)对比观察增生型糖尿病视网膜病变(PDR).眼科新进展,2017,37:52-55.
[7]Michalska-Malecka K,Heinke Knudsen A.Optical coherence tomography angiography in patients with diabetic retinopathy treated with anti-VEGF intravitreal injections:Case report J.Medicine(Baltimore),2017,96:e8379.
[8]曾苗,陈晓,宋艳萍,丁琴,陈中山.视网膜中央静脉阻塞患眼光相干断层扫描血管成像与荧光素眼底血管造影结果对比分析.中华眼底病杂志,2016,32:362-366.
[9]Samara WA,Shahlaee A,Sridhar J,et al.Quantitative Optical Coherence Tomography Angiography Features and Visual Function in Eyes With Branch Retinal Vein Occlusion.Am JOphthalmol,2016,166:76-83.
[10]孙晓丽,丛春霞,李立,等.光学相干断层扫描血管成像与传统多模式眼底成像对渗出型老年性黄斑变性脉络膜新生血管诊断与活动性判断的对比观察.中华眼底病杂志,2017,33:10-14.
[11]马楠,陈有信,巩迪,等.息肉样脉络膜血管病变吲哚青绿血管造影与光相干断层扫描血管成像图像特征对比观察.中华眼底病杂志,2015,31:421-424.
[12]Kim JY,Kwon OW,Oh HS,et al.Optical coherence tomographyangiography in patients with polypoidal choroidal vasculopathy.J.Graefes Arch Clin Exp Ophthalmol,2016,254:1505-1510.
[13]Takayama K,Ito Y,Kaneko H,et al.Comparison of indocyanine green angiography and optical coherence tomography angiography in polypoidal choroidal vasculopathy.J.Eye(Lond),2017,31:45-52.
[14]王敏.利用光相干断层扫描血管成像技术优势提升视网膜脉络膜血管疾病认知水平.中华眼底病杂志,2016,32:353-356.
[15]李倩,陈长征,苏钰,等.OCT血管成像术在病理性近视黄斑新生血管病变诊疗中的应用价值.中华实验眼科杂志,2016,34:1102-1106.
[16]莫宾,周海英,焦璇,等.中心性浆液性脉络膜视网膜病变的OCTA特点及与ICGA的比较分析.国际眼科杂志,2017,17:1351-1355.
[17]Corbelli E,Carnevali A,Marchese A,et al.Optical Coherence Tomography Angiography Features of Angioid Streaks.J,Retina,2017,0:1-9.
[18]Baumal CR,de Carlo TE,Waheed NK,et al.Sequential Optical Coherence Tomography Angiography for Diagnosis and Treatment of Choroidal Neovascularization in Multifocal Choroiditis.JAMA Ophthalmol,2015,133:1078-1090.
[19]Triolo G,Rabilol A,Shemonski ND,et al.Optical coherence tomagraphy angiography Macular and Peripapillary Vessel Perfusion Density in Healthy Subject,Glaucoma Suspects,and Glaucoma patients.J.Invest Ophthalmol Vis Sci,2017,58:5713-5722.
[20]Zhang S,Wu C,Liu L,et al.Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary AngleClosure Glaucoma.Am J Ophthalmol,2017,182:194-200.
[21]Zivkovic M,Dayanir V,Kocaturk T,et al.Foveal Avascular Zone in Normal Tension Glaucoma Measured by Optical Coherence Tomography Angiography.J.Biomed Res Int,2017,2017:3079141.
[22]朱佩文,邹雪香,刘康,等.成光学相干断层扫描血管造影(OCTA)在角膜厚度测量中的临床研究.眼科新进展,2017,37:732-735.
[23]ANG M,CAI Y,SHAHIPASAND S,SIM DA,KEANE PA,SNGCC,et al.En face optical coherence tomography angiography for corneal neovascularisation.Br JOphthalmol,2016,100:616-621.
[24]Chien JL,Sioufi K,Ferenczy S,et al.Optical Coherence Tomography Angiography Features of Iris Racemose Hemangioma in 4 Cases.JAMA Ophthalmol,2017,135:1106-1110.
[25]Marcus Ang,Anna C.S.Tan,Chui Ming Gemmy Cheung,et al.Opticla coherence tomography angiography:a review of current and future clinical applications.J.Graefe’s Arch Clin Exp Ophthalmol,2018,256:237-245.
[26]Akahori T,Iwase T,Yamamoto K,et al.Macular displacement after vitrectomy in eyes with idiopathic macular hole determined by optical coherence tomography angiography.Am J Ophthalmol,2018 Mar 2.pii:S0002-9394(18)30096-5.
[27]Lyu S,Zhang M,Wang RK,et al.Analysis of the characteristics of optical coherence tomography angiography for retinal cavernous hemangioma:A case report.J.Medicine(Baltimore),2018,97:e9940.
[28]Lee SY,Cheng JL,Gehrs KM,et al.Choroidal Features of Acute Macular Neuroretinopathy via Optical Coherence Tomography Angiography and Correlation with Serial Multimodal Imaging.JAMA Ophthalmol,2017,135:1177-1183.
[29]Lonngi M,Velez FG,Tsui I,et al.Spectral-Domain Optical Coherence Tomography Angiography in Children With Amblyopia.JAMA Ophthalmol,2017,135:1086-1091.
[30]Campbell JP,Nudleman E,Yang J,et al.Handheld Optical Coherence Tomography Angiography and Ultra-Wide-Field Optical Coherence Tomography in Retinopathy of Prematurity.JAMA Ophthalmol,2017,135:977-981.