血清免疫球蛋白检测对肝衰竭诊断价值研究
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摘要
目的观察血清免疫球蛋白检测对肝衰竭诊断的价值。方法选取2017年7月至2018年7月在本院诊治的76例肝衰竭患者临床资料(设观察组),另取本院体检的76例健康者(设对照组),均行血清免疫球蛋白测定,比较两组血清免疫球蛋白水平。结果与对照组比,观察组IgA(13.28±2.31)g/L、IgG(28.02±3.65)g/L、IgM(12.56±2.03)g/L均较高(P<0.05);与治疗前比,早、中、晚期的各项免疫球蛋白治疗后的水平均降低(P<0.05)。结论血清免疫球蛋白检测不仅能作为肝衰竭诊断指标,还能判断病情的严重程度及预后。
Objective To observe the value of serum immunoglobulin assay in the diagnosis of liver failure. Methods The clinical data of 76 patients with liver failure diagnosed in the Hospital between July 2017 and July 2018 were enrolled(as the observation group). Another 76 healthy subjects who had received physical examinations in the Hospital were selected(as the control group). Serum immunoglobulin assay was used to compare the serum immunoglobulin levels in the two groups. Results Compared with the control group, the levels of IgA, IgG and IgM in the observation group were higher, which were respectively(13.28±2.31)g/L,(28.02±3.65)g/L and(12.56±2.03)g/L(P<0.05). The levels of immunoglobulin after early, middle and late treatment were all shown to be lower than before treatment(P<0.05). Conclusion Serum immunoglobulin assay can not only serve as a diagnostic index for liver failure, but also a basis for determining its severity and prognosis.
Objective To observe the value of serum immunoglobulin assay in the diagnosis of liver failure. Methods The clinical data of 76 patients with liver failure diagnosed in the Hospital between July 2017 and July 2018 were enrolled(as the observation group). Another 76 healthy subjects who had received physical examinations in the Hospital were selected(as the control group). Serum immunoglobulin assay was used to compare the serum immunoglobulin levels in the two groups. Results Compared with the control group, the levels of IgA, IgG and IgM in the observation group were higher, which were respectively(13.28±2.31)g/L,(28.02±3.65)g/L and(12.56±2.03)g/L(P<0.05). The levels of immunoglobulin after early, middle and late treatment were all shown to be lower than before treatment(P<0.05). Conclusion Serum immunoglobulin assay can not only serve as a diagnostic index for liver failure, but also a basis for determining its severity and prognosis.
引文
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[11]张勤.血清IgA、IgM和IgG水平在肝病诊断中的意义[J].数理医药学杂志,2015,28(2):167-168.
[12]黄丽庆,黄启强,谭惠璇.乙型肝炎患者免疫球蛋白检验的临床意义探讨[J].中国医学创新,2015,12(36):25-26.
[2]陈煜,李珊珊,段钟平.慢加急性肝衰竭的研究进展[J].北京医学,2015,37(9):816-819.
[3]张惠菊.老年慢性乙型肝炎患者免疫球蛋白及凝血酶原检测分析[J].医学理论与实践,2017,30(10):1512-1513.
[4]羊措.血清免疫球蛋白检验在肝衰竭诊断中的应用分析[J].临床检验杂志,2017,6(3):530-531.
[5]孙鑫涛.血清免疫球蛋白检验在肝衰竭患者中的临床意义[J].实用医技杂志,2018,25(1):55-56.
[6]苏金花,罗新.血清免疫球蛋白测定在肝衰竭的诊断价值[J].中国医药科学,2018,8(5):137-139.
[7]林孟新,苏智军,郭如意.乙型肝炎患者血清免疫球蛋白和补体C3/C4检测的意义[J].实用肝脏病杂志,2015,18(2):182-183.
[8]周招华.血清免疫球蛋白在乙型肝炎患者中的检验意义分析[J].当代医学,2017,23(20):60-61.
[9]李红娟.血清免疫球蛋白检验在肝衰竭患者中的应用意义探究[J].中国实用医药,2016,11(19):40-41.
[10]高冬梅.血清免疫球蛋白检验在肝衰竭诊断中的应用价值分析[J].系统医学,2018,3(2):17-18.
[11]张勤.血清IgA、IgM和IgG水平在肝病诊断中的意义[J].数理医药学杂志,2015,28(2):167-168.
[12]黄丽庆,黄启强,谭惠璇.乙型肝炎患者免疫球蛋白检验的临床意义探讨[J].中国医学创新,2015,12(36):25-26.