腹腔镜手术治疗卵巢良性肿瘤的疗效
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摘要
目的探讨腹腔镜手术治疗卵巢良性肿瘤患者的治疗效果。方法选取2016年10月至2018年10月间四川省遂宁市第一人民医院收治的96例卵巢良性癌患者作为本次研究对象,采用随机数表法分为对照组和观察组,每组48例。对照组患者采用常规开腹手术治疗,观察组患者采取腹腔镜手术治疗,比较两组患者的手术情况、卵巢功能和神经内分泌指标。结果观察组手术时间、术中出血量、住院时间和肛门排气时间等明显低于对照组,差异均有统计学意义(均P <0. 05)。手术前,两组患者雌二醇(E2)、黄体生成素(LH)和卵泡刺激素(FSH)比较,差异无统计学意义(P>0. 05)。手术后,观察组患者E2、LH和FSH指标均明显优于对照组患者,差异均有统计学意义(均P <0. 05)。手术前,两组患者胰高血糖素、β-内啡肽(β-EP)、皮质醇(COR)和促甲状腺激素(TSH)比较,差异无统计学意义(P> 0. 05)。手术后,观察组患者胰高血糖素、β-EP、COR和TSH指标明显优于对照组患者,差异均有统计学意义(均P <0. 05)。结论采用腹腔镜手术治疗卵巢良性肿瘤患者,能有效降低术中出血量,改善卵巢功能,降低应激反应,值得在临床上推广。
Objective To observe and analyze the efficacy of laparoscopic surgery for benign ovarian tumors. Methods A total of 96 patients with benign ovarian tumors who were treated at First People's Hospital of Suining from October 2016 to October 2018 were selected as the research subjects and were divided into an observation group and a control group by the random number method. The observation group was treated by laparoscopy and the control group was treated by routine laparotomy. The operation conditions,ovarian function and neuroendocrine indexes were compared between the two groups. Result The operation time,intraoperative bleeding volume,hospital stay and anal exhaust time were significantly lower in the observation group than in the control group(all P < 0. 05). Before the surgery,there was no significant difference in estradiol(E2),luteinizing hormone(LH) and follicle stimulating hormone(FSH) indexes between the two groups before the surgery(P > 0. 05). After the operation,E2,LH and FSH indexes were better in the observation group than in the control group(all P < 0. 05). There was no significant difference in the indexes of glucagon,beta-endorphin(beta-EP),cortisol(COR) and thyrotropin(TSH)between the two groups before the surgery(P > 0. 05). After the operation,the above three indexes were better in the observation group than in the control group(P > 0. 05). Conclusion Laparoscopic surgery for benign ovarian tumors can effectively reduce intraoperative bleeding,improve ovarian function and reduce stress response,which is worthy of clinical promotion.
Objective To observe and analyze the efficacy of laparoscopic surgery for benign ovarian tumors. Methods A total of 96 patients with benign ovarian tumors who were treated at First People's Hospital of Suining from October 2016 to October 2018 were selected as the research subjects and were divided into an observation group and a control group by the random number method. The observation group was treated by laparoscopy and the control group was treated by routine laparotomy. The operation conditions,ovarian function and neuroendocrine indexes were compared between the two groups. Result The operation time,intraoperative bleeding volume,hospital stay and anal exhaust time were significantly lower in the observation group than in the control group(all P < 0. 05). Before the surgery,there was no significant difference in estradiol(E2),luteinizing hormone(LH) and follicle stimulating hormone(FSH) indexes between the two groups before the surgery(P > 0. 05). After the operation,E2,LH and FSH indexes were better in the observation group than in the control group(all P < 0. 05). There was no significant difference in the indexes of glucagon,beta-endorphin(beta-EP),cortisol(COR) and thyrotropin(TSH)between the two groups before the surgery(P > 0. 05). After the operation,the above three indexes were better in the observation group than in the control group(P > 0. 05). Conclusion Laparoscopic surgery for benign ovarian tumors can effectively reduce intraoperative bleeding,improve ovarian function and reduce stress response,which is worthy of clinical promotion.
引文
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[3]张玉倩.腹腔镜下子宫动脉阻断术联合宫骶韧带切断术治疗子宫腺肌病的临床疗效及对卵巢血流的影响[J].中国妇幼保健,2019,34(6):1411-1413.
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[6]赵维楠,陈淑霞.腹腔镜与开腹手术治疗卵巢良性肿瘤对患者卵巢功能及神经内分泌功能的影响[J].实用癌症杂志,2018,33(6):1014-1017.
[7] Amirlatifi N,Aalami-Harandi P,Day B. Dual usage of 5mm laparoscope for abdominal entry and cystoscopy during robotic assisted laparoscopic hysterectomy:Safe alternative to traditional cystoscopy[J]. J Minim Invas Gyn,2018,25(7):126-127.
[8]马园园,杨敏,孙延霞.腹腔镜微创手术对卵巢良性肿瘤患者神经内分泌激素及卵巢功能的影响分析[J].贵州医药,2019,43(2):244-246.
[9]胡先娥,龙凤.腹腔镜手术治疗良性卵巢肿瘤对机体卵巢功能、免疫功能的影响[J].中国继续医学教育,2019,11(5):79-81.
[10]秀荣.妇科腹腔镜手术治疗良性卵巢肿瘤临床效果观察[J].世界最新医学信息文摘,2019,15(18):89.
[2] Xu X,Huang C,Mou Y,et al. Intra-corporeal hand-sewn esophagojejunostomy is a safe and feasible procedure for totally laparoscopic total gastrectomy:short-term outcomes in 100 consecutive patients[J]. Surg Endosc,2018,32(6):2689-2695.
[3]张玉倩.腹腔镜下子宫动脉阻断术联合宫骶韧带切断术治疗子宫腺肌病的临床疗效及对卵巢血流的影响[J].中国妇幼保健,2019,34(6):1411-1413.
[4] Zheng S,Sun P,Liu X,et al. Efficacy and safety of laparoscopic splenectomy and esophagogastric devascularization for portal hypertension:A single-center experience[J]. Medicine,2018,97(50):334-336.
[5]刘进,刘九平.腹腔镜治疗卵巢良性肿瘤的有效性及安全性[J].当代医学,2019,4(9):152-153.
[6]赵维楠,陈淑霞.腹腔镜与开腹手术治疗卵巢良性肿瘤对患者卵巢功能及神经内分泌功能的影响[J].实用癌症杂志,2018,33(6):1014-1017.
[7] Amirlatifi N,Aalami-Harandi P,Day B. Dual usage of 5mm laparoscope for abdominal entry and cystoscopy during robotic assisted laparoscopic hysterectomy:Safe alternative to traditional cystoscopy[J]. J Minim Invas Gyn,2018,25(7):126-127.
[8]马园园,杨敏,孙延霞.腹腔镜微创手术对卵巢良性肿瘤患者神经内分泌激素及卵巢功能的影响分析[J].贵州医药,2019,43(2):244-246.
[9]胡先娥,龙凤.腹腔镜手术治疗良性卵巢肿瘤对机体卵巢功能、免疫功能的影响[J].中国继续医学教育,2019,11(5):79-81.
[10]秀荣.妇科腹腔镜手术治疗良性卵巢肿瘤临床效果观察[J].世界最新医学信息文摘,2019,15(18):89.