早产儿胎龄和体重对儿童糖尿病的预测作用
|
摘要
目的探究并分析早产儿胎龄和体重对儿童糖尿病的预测作用。方法回顾性分析200例早产儿的临床资料。按照早产儿的胎龄分为A1、A2、A3、A4组,根据出生体重分为B1、B2、B3、B4组,根据喂养方式分为C1、C2、C3组。跟踪随访15年后,记录早产儿儿童糖尿病的发病率。结果 28~30周胎龄组早产儿儿童糖尿病发病率为80.0%,明显高于其他胎龄组;出生体重≤999g早产儿发病率为80.0%,较其他组早产儿高;人工喂养组早产儿发病率为60.8%,明显高于其余两组(P均<0.05),具有统计学意义。结论儿童糖尿病的发病率与早产儿胎龄和出生体重密切相关。
Objective To explore and analyze the prediction function of gestational age and body weight of premature infants on diabetes in children. Methods The retrospective analysis of clinical data was taken,including 200 cases of premature infants. According to their gestational age,they were divided into A1,A2,A3,A4 four groups,with B1,B2,B3,B4 four groups according to their birth weight,C1,C2,C3 three groups according to the feeding patterns. After a follow-up visit for 15 years,records were written down on the incidences of diabetes in these children. Results The incidence of diabetes was 80% in group of premature infants with 28 ~30 weeks' gestational age,significantly higher than other age groups. So was the morbidity rate of those with birth weight ≤999g,which accounted for 80. 0%. The morbidity rate of premature infants,who were treated with artificial feeding was 60. 8%,significantly higher than the other two groups( P < 0. 05). Besides,the morbidity rate in group of infants with non-nutritive sucking accounted for 50. 9%. Conclusion The incidence of diabetes in children is closely related to the gestational age and birth weight of these premature infants.
Objective To explore and analyze the prediction function of gestational age and body weight of premature infants on diabetes in children. Methods The retrospective analysis of clinical data was taken,including 200 cases of premature infants. According to their gestational age,they were divided into A1,A2,A3,A4 four groups,with B1,B2,B3,B4 four groups according to their birth weight,C1,C2,C3 three groups according to the feeding patterns. After a follow-up visit for 15 years,records were written down on the incidences of diabetes in these children. Results The incidence of diabetes was 80% in group of premature infants with 28 ~30 weeks' gestational age,significantly higher than other age groups. So was the morbidity rate of those with birth weight ≤999g,which accounted for 80. 0%. The morbidity rate of premature infants,who were treated with artificial feeding was 60. 8%,significantly higher than the other two groups( P < 0. 05). Besides,the morbidity rate in group of infants with non-nutritive sucking accounted for 50. 9%. Conclusion The incidence of diabetes in children is closely related to the gestational age and birth weight of these premature infants.
引文
[1]程亚颖,宫丽芬,宋光耀,等.不同胎龄及体重新生儿血Ghrelin、胰岛素样生长因子-1、胰岛素样生长因子结合蛋白-3、胰岛素水平检测分析[J].中国妇幼保健,2011,26(26):4050
[2]牟春笋,徐文菊,王明月,等.妊娠期糖尿病对新生儿出生结局的影响[J].山东医药,2009,49(41):59
[3]茅李莉,肖新华.宫内发育环境与成年期糖代谢关系的表观遗传学机制[J].中国糖尿病杂志,2012,20(9):716
[4]Berengere C,Valwnie A,Isabelle G.Nutritional programming affects hypothalamic organization and early response to Leptin[J].Endocrinology,2010,151(2):702
[5]谢贵阳,王胜辉,袁新宇,等.新生儿糖调节异常260例临床分析[J].中国现代医生,2010,48(27):117
[6]茅李莉.宫内发育环境与糖代谢异常的表观遗传学研究[D].北京:北京协和医学院,2011
[2]牟春笋,徐文菊,王明月,等.妊娠期糖尿病对新生儿出生结局的影响[J].山东医药,2009,49(41):59
[3]茅李莉,肖新华.宫内发育环境与成年期糖代谢关系的表观遗传学机制[J].中国糖尿病杂志,2012,20(9):716
[4]Berengere C,Valwnie A,Isabelle G.Nutritional programming affects hypothalamic organization and early response to Leptin[J].Endocrinology,2010,151(2):702
[5]谢贵阳,王胜辉,袁新宇,等.新生儿糖调节异常260例临床分析[J].中国现代医生,2010,48(27):117
[6]茅李莉.宫内发育环境与糖代谢异常的表观遗传学研究[D].北京:北京协和医学院,2011