热毒宁治疗儿童病毒性脑炎的疗效探讨
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摘要
目的研究观察热毒宁治疗儿童病毒性脑炎的疗效。方法选取自2015年1月—2018年1月期间,该院儿科收治并确诊为病毒性脑炎的儿童76例,随机分为对照组与观察组。对照组采用降颅压,常规对症支持疗法,而观察组在对照组的基础上加用热毒宁注射液注射治疗。比较两组患儿的总有效率及临床症状的改善情况。结果对照组38例研究对象中,11例完全治愈及18例治疗后好转,总有效率达76.3%,而观察组38例研究对象中,20例完全治愈及15例治疗后有所好转,其的总有效率高达92.1%,观察组的总有效率明显高于对照组,二者的差异有统计学意义(χ~2=3.298,P<0.05);观察组患儿发热、呕吐及头痛的持续时间分别为(2.56±1.01)d、(3.17±0.61)d、(3.11±0.10)d,而对照组患儿的发热、呕吐及头痛的持续时间分别为(3.14±1.22)d、(4.34±0.88)d、(3.83±0.14)d,观察组患儿临床症状改善所用时间明显少于对照组所用时间,两组间的差异有统计学意义(t=1.376、1.398、1.964,P<0.05)。结论应用热毒宁治疗儿童病毒性脑炎,能够明显的改善患儿的临床症状及体征,起效快且疗程短,值得临床上推广应用。
Objective To study the efficacy of Resin in the treatment of viral encephalitis in children. Methods From January 2015 to January 2018, 76 children with pediatrics admitted to the hospital and diagnosed as viral encephalitis were randomly divided into control group and observation group. The control group was treated with intracranial pressure reduction and conventional symptomatic supportive therapy, while the observation group was treated with heat-toxic injection on the basis of the control group. The total effective rate and improvement of clinical symptoms were compared between the two groups. Results Of the 38 subjects in the control group, 11 were completely cured and 18 were improved after treatment. The total effective rate was 76.3%. Of the 38 subjects in the observation group, 20 were completely cured and 15 were improved after treatment. The total effective rate was as high as 92.1%. The total effective rate of the observation group was significantly higher than that of the control group. The difference between the two groups was significant, which was statistically significant(χ~2=3.298,P<0.05). The observation group had fever, vomiting and headache durations were(2.56 ±1.01)d,(3.17 ±0.61)d,(3.11 ±0.10)d, while the duration of fever, vomiting and headache in the control group were(3.14 ±1.22)d,(4.34 ±0.88)d,(3.83±0.14)d. The time spent on the improvement of clinical symptoms in the observation group was significantly less than that in the control group, between the two groups.The difference was statistically significant(t=1.376,1.398,1.964,P<0.05). Conclusion The application of Resin in the treatment of children with viral encephalitis can significantly improve the clinical symptoms and signs of children, with rapid onset and short course of treatment, which is worthy of clinical application.
Objective To study the efficacy of Resin in the treatment of viral encephalitis in children. Methods From January 2015 to January 2018, 76 children with pediatrics admitted to the hospital and diagnosed as viral encephalitis were randomly divided into control group and observation group. The control group was treated with intracranial pressure reduction and conventional symptomatic supportive therapy, while the observation group was treated with heat-toxic injection on the basis of the control group. The total effective rate and improvement of clinical symptoms were compared between the two groups. Results Of the 38 subjects in the control group, 11 were completely cured and 18 were improved after treatment. The total effective rate was 76.3%. Of the 38 subjects in the observation group, 20 were completely cured and 15 were improved after treatment. The total effective rate was as high as 92.1%. The total effective rate of the observation group was significantly higher than that of the control group. The difference between the two groups was significant, which was statistically significant(χ~2=3.298,P<0.05). The observation group had fever, vomiting and headache durations were(2.56 ±1.01)d,(3.17 ±0.61)d,(3.11 ±0.10)d, while the duration of fever, vomiting and headache in the control group were(3.14 ±1.22)d,(4.34 ±0.88)d,(3.83±0.14)d. The time spent on the improvement of clinical symptoms in the observation group was significantly less than that in the control group, between the two groups.The difference was statistically significant(t=1.376,1.398,1.964,P<0.05). Conclusion The application of Resin in the treatment of children with viral encephalitis can significantly improve the clinical symptoms and signs of children, with rapid onset and short course of treatment, which is worthy of clinical application.
引文
[1]彭献华.更昔洛韦联合热毒宁治疗小儿病毒性脑炎疗效分析[J].北方药学,2017,14(1):56-57.
[2]毛媛媛,赛买提·玉素甫.热毒宁注射液治疗以癫痫为主要表现的病毒性脑炎患儿的疗效观察[J].吉林医学,2015,36(4):698-699.
[3]米克拉依·加帕尔.热毒宁治疗癫痫状病毒性脑炎42例临床观察[J].中国民族民间医药,2015,24(20):46.
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[5]施洪美.热毒宁注射液治疗儿童发热性疾病效果观察及安全性评价[J].中外医学研究,2017,15(14):122-123.
[6]李吉平.热毒宁注射液应用于230例儿童发热疗效观察分析[J].北方药学,2016,13(11):45.
[7]徐艳梅.儿童病毒性脑炎112例的临床分析[J].中国妇幼健康研究,2016,27(8):950-952.
[8]孙艳.小儿病毒性脑炎临床治疗分析[J].按摩与康复医学,2016,7(4):65-66.
[9]张薇,齐共健.丙种球蛋白与热毒宁治疗手足口病并发病毒性脑炎的效果比较[J].中国实用神经疾病杂志,2016,19(5):118-119.
[10]张文勇,周泉良,施传娥,等.热毒宁治疗小儿病毒性脑炎69例疗效观察[J].心理医生,2015,21(10):45-46.
[2]毛媛媛,赛买提·玉素甫.热毒宁注射液治疗以癫痫为主要表现的病毒性脑炎患儿的疗效观察[J].吉林医学,2015,36(4):698-699.
[3]米克拉依·加帕尔.热毒宁治疗癫痫状病毒性脑炎42例临床观察[J].中国民族民间医药,2015,24(20):46.
[4]贾耀丽.小儿病毒性脑炎采用更昔洛韦联合热毒宁治疗的效果和安全性分析[J].中国现代药物应用,2016,10(2):161-162.
[5]施洪美.热毒宁注射液治疗儿童发热性疾病效果观察及安全性评价[J].中外医学研究,2017,15(14):122-123.
[6]李吉平.热毒宁注射液应用于230例儿童发热疗效观察分析[J].北方药学,2016,13(11):45.
[7]徐艳梅.儿童病毒性脑炎112例的临床分析[J].中国妇幼健康研究,2016,27(8):950-952.
[8]孙艳.小儿病毒性脑炎临床治疗分析[J].按摩与康复医学,2016,7(4):65-66.
[9]张薇,齐共健.丙种球蛋白与热毒宁治疗手足口病并发病毒性脑炎的效果比较[J].中国实用神经疾病杂志,2016,19(5):118-119.
[10]张文勇,周泉良,施传娥,等.热毒宁治疗小儿病毒性脑炎69例疗效观察[J].心理医生,2015,21(10):45-46.