呼气负压技术与常规肺功能检测方法的相关性研究
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摘要
目的探讨呼气负压技术(NEP)与常规肺通气功能检测方法的相关性。方法 100例受试者用NEP检测呼气气流受限(EFL),测定气流受限指数(FL%),采用3分法进行EFL评分。所有受试者同时进行常规肺通气功能测试,测定FEV1、FEV1占预计值%(FEV1%)、FEV/FVC,根据FEV1%对常规肺通气功能分级,应用Pearson检验分析FL%与FEV1、FEV1%、FEV/FVC的相关性,用Spearman检验分析3分法EFL评分和FEV1%的相关性。结果 FL%分别与FEV1、FEV1%、FEV/FVC存在负相关(r分别为-0.70、-0.73,r=-0.67,P均<0.01),其中与FEV1%相关性最强;3分法EFL评分和FEV1%存在负相关(r=-0.74,P<0.01),提示气流受限指数随着气流阻塞程度的加重而增加。结论 NEP与常规肺功能检测方法具有相关性,且操作较常规肺功能简单,具有较好的临床应用前景。
Objective To investigate the correlation between negative pressure technique and routine pulmonary function. Methods One hundred subjects, who were tested by both NEP and routine pulmonary function, were included in this study. FL% and 3-point of EFL scores were determined by NEP. Correlation between two detection methods was assessed with Pearson and Spearman correlation analysis. Results FEV1, FEV1% and FEV/FVC were significantly correlated with FL%(r=-0.70、-0.73, and-0.67, respectively, P<0.01). There was a negative correlation between 3-point of EFL scores and FEV1% classification(r=-0.74, P<0.01), which suggested that the airflow limitation index would be increased according to the increase of airflow obstruction. Conclusion There was a correlation between NEP and routine pulmonary function. The NEP is convenient and has good prospects for clinical application.
Objective To investigate the correlation between negative pressure technique and routine pulmonary function. Methods One hundred subjects, who were tested by both NEP and routine pulmonary function, were included in this study. FL% and 3-point of EFL scores were determined by NEP. Correlation between two detection methods was assessed with Pearson and Spearman correlation analysis. Results FEV1, FEV1% and FEV/FVC were significantly correlated with FL%(r=-0.70、-0.73, and-0.67, respectively, P<0.01). There was a negative correlation between 3-point of EFL scores and FEV1% classification(r=-0.74, P<0.01), which suggested that the airflow limitation index would be increased according to the increase of airflow obstruction. Conclusion There was a correlation between NEP and routine pulmonary function. The NEP is convenient and has good prospects for clinical application.
引文
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[8]Chen R,Chen RC,Liu J,et al.To compare negative expiratory pressure technique with conventional tests in detecting expiratory flow limitation in chronic obstructive pulmonary diseases patients[J].Zhonghua Nei Ke Za Zhi,2010,49(2):122-124.
[9]Eltayara L,Becklake MR,Volta CA,et al.Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease[J].Am J Respir Crit Care Med,1996,154(6 Pt 1):1726-1734.
[10]陈宇清,周新,蔡映云.应用呼气负压技术检测慢性阻塞性肺疾病患者呼气流速受限[J].中华结核和呼吸杂志,2003,26(2):126-127.
[2]Koulouris NG.Negative expiratory pressure:a new tool[J].Monaldi Arch Chest Dis,2002,57(1):69-75.
[3]Bestall JC,Paul EA,Garrod R,et al.Usefulness of the Medical Research Council(MRC)dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease[J].Thorax,1999,54(7):581-586.
[4]Doherty DE.慢性阻塞性肺疾病患者的预后评估[J].中华医学杂志,2006,86(41):2887-2889.
[5]Valta P,Corbeil C,Lavoie A,et al.Detection of expiratory flow limitation during mechanical ventilation[J].Am J Respir Crit Care Med,1994,150(5 Pt 1):1311-1317.
[6]Tauber E,Fazekas T,Eichler I,et al.Negative expiratory pressure:a new tool for evaluating lung function in children[J].Pediatr Pulmonol,2003,35(3):162-168.
[7]Baydur A,Wilkinson L,Mehdian R,et al.Extrathoracic expiratory flow limitation in obesity and obstructive and restrictive disorders:effects of increasing negative expiratory pressure[J].Chest,2004,125(1):98-105.
[8]Chen R,Chen RC,Liu J,et al.To compare negative expiratory pressure technique with conventional tests in detecting expiratory flow limitation in chronic obstructive pulmonary diseases patients[J].Zhonghua Nei Ke Za Zhi,2010,49(2):122-124.
[9]Eltayara L,Becklake MR,Volta CA,et al.Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease[J].Am J Respir Crit Care Med,1996,154(6 Pt 1):1726-1734.
[10]陈宇清,周新,蔡映云.应用呼气负压技术检测慢性阻塞性肺疾病患者呼气流速受限[J].中华结核和呼吸杂志,2003,26(2):126-127.