光动力三阶段治疗尖锐湿疣的临床疗效分析
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摘要
目的探讨光动力三阶段治疗尖锐湿疣的临床疗效。方法将80例尖锐湿疣患者随机分为2组,光动力三阶段治疗组40例采用CO_2激光+光动力+薄芝糖肽治疗,CO_2激光治疗组40例单纯采用CO_2激光治疗。2组均在末次治疗后连续随访6个月,观察治疗效果及复发情况。结果光动力三阶段治疗组的治愈率高于CO_2激光治疗组,复发率低于CO_2激光治疗组,差异均有统计学意义(P<0.05)。无明显不良反应,疼痛1 d～3 d可缓解。结论光动力三阶段治疗方案对尖锐湿疣疗效显著,值得临床推广。
Objective To investigate the clinical efficacy of photodynamic three phases therapy in the treatment of condyloma acuminatum.Methods 80 patients diagnosed with condyloma acuminatum are randomLy divided into two groups.40 patients with CA were treated with combination CO_2 laser,ALA-PDT and bozhi glycopeptides,and other 40 cases were treated with CO_2 laser only respectively.The follow-up period of two groups was 6 months continuously after the last treatment and the curative effect and recurrence were observed.Results The cure rate and recurrence rate of the group of photodynamic three phases was significantly higher than the group of CO_2 laser.The cure rate and recurrence rate of the two groups were statistically significant(P<0.05).There were few patients who had obvious adverse reaction,and the pain can alleviate edema 1day to 3 days.Conclusion These findings indicate that photodynamic three phases therapy has significant efficacy on condyloma acuminatum,which is worthy of clinical promotion.
Objective To investigate the clinical efficacy of photodynamic three phases therapy in the treatment of condyloma acuminatum.Methods 80 patients diagnosed with condyloma acuminatum are randomLy divided into two groups.40 patients with CA were treated with combination CO_2 laser,ALA-PDT and bozhi glycopeptides,and other 40 cases were treated with CO_2 laser only respectively.The follow-up period of two groups was 6 months continuously after the last treatment and the curative effect and recurrence were observed.Results The cure rate and recurrence rate of the group of photodynamic three phases was significantly higher than the group of CO_2 laser.The cure rate and recurrence rate of the two groups were statistically significant(P<0.05).There were few patients who had obvious adverse reaction,and the pain can alleviate edema 1day to 3 days.Conclusion These findings indicate that photodynamic three phases therapy has significant efficacy on condyloma acuminatum,which is worthy of clinical promotion.
引文
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[5]张云凤,缪飞,王宏伟,等.氨基酮戊酸光动力治疗尖锐湿疣局部免疫反应的研究[J].中华皮肤科杂志,2013,46(5):309-312.
[2]中华医学会皮肤性病学分会性病学组.尖锐湿疣临床诊疗与防治指南(一)[J].中国艾滋病性病,2015,21(2):172-173.
[3]刘国艳,庞云燕,栾青霞,等.自拟扶正祛疣汤联合CO2激光治疗尖锐湿疣的疗效[J].中国中西医结合皮肤性病学杂志,2014,13(1):34-36.
[4]GIOMI B,MASTROLORENZO A,TIRADRITTI L,et al.Off label treatments of genital warts:The role of photodynamic therapy[J].G Ital Dermatol Venereol,2012,147(5):467-474.
[5]张云凤,缪飞,王宏伟,等.氨基酮戊酸光动力治疗尖锐湿疣局部免疫反应的研究[J].中华皮肤科杂志,2013,46(5):309-312.