一期腹腔镜结肠癌根治术联合肝转移灶切除术治疗同时性结肠癌肝转移一例
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摘要
收集2017年8月南京医科大学第二附属医院普外科收治的1例乙状结肠癌伴肝转移患者的临床病例资料。对于不可切除的结肠癌肝转移患者,经转化治疗后行一期全腹腔镜切除原发灶及肝转移灶是安全的,近期疗效较好。
The clinical data of one patient with sigmoid colon cancer and synchronous multiple liver metastases who was admitted to the Department of General Surgery, the Second Affiliated Hospital of Nanjing Medical University in August 2017 were collected. For the patient with unresectable liver metastasis of colonic neoplasms, I-stage laparoscopic resection of colonic neoplasms and synchronous liver metastasis after conversion therapy is safe. The short-term therapeutic effect is better.
The clinical data of one patient with sigmoid colon cancer and synchronous multiple liver metastases who was admitted to the Department of General Surgery, the Second Affiliated Hospital of Nanjing Medical University in August 2017 were collected. For the patient with unresectable liver metastasis of colonic neoplasms, I-stage laparoscopic resection of colonic neoplasms and synchronous liver metastasis after conversion therapy is safe. The short-term therapeutic effect is better.
引文
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[7]忠诚,苏冀.结直肠癌肝转移的转化治疗策略[J/CD].中华结直肠疾病电子杂志,2013,2(5):217-220.
[8]Haraldsdottir S,Wu C,Bloomston M,et al.What is the optimal neoadjuvant treatment for liver metastasis?[J].Ther Adv Med Oncol,2013,5(4):221-234.
[9]Yin Z,Liu C,Chen Y,et al.Timing of hepatectomy in resectable synchronous colorectal liver metastases(SCRLM):Simultaneous or delayed?[J].Hepatology,2013,57(6):2346-2357.
[10]杨亮亮,任黎.同时性结肠癌肝转移转化治疗后一期切除原发灶及肝转移灶[J].中华消化外科杂志,2016,15(2):185-190.
[11]Waisberg J,Lvankovics IG.Liver-first approach of colorectal cancer with synchronous hepatic metastases:A reverse strategy[J].World J Hepatol,2015,7(11):1444-1449.
[12]Rahbari NN,Bork U,Sch?lch S,et al.Metastatic Spread Emerging From Liver Metastases of Colorectal Cancer:Does the Seed Leave the Soil Again?[J].Ann Surg,2016,263(2):345-352.
[13]Wei M,He Y,Wang J,et al.Laparoscopic versus open hepatectomy with or without synchronous colectomy for colorectal liver metastasis:a meta-analysis[J].PLoS One,2014,9(1):e87461.
[14]戴朝六,徐锋.个体化治疗直肠癌同时性肝转移[J].中华消化外科杂志,2014,13(3):175-179.
[2]Ye Lc,Liu TS,Ren L,et a1.Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-1imited metastases[J].J Clin Oncol,2013,31(16):1931-1938.
[3]顾晋.结直肠癌规范化外科治疗的问题与对策[J].中华消化外科杂志,2015,14(6):441-444.
[4]Adam R,de Gramont A,Figueras J,et al.Managing synchronous liver metastases from colorectal cancer:a multidiciplinary international consensus[J].Cancer Treat Rev,2015,41(9):729-741.
[5]中华医学会外科学分会胃肠外科学组,中华医学会外科学分会结直肠肛门外科学组,中国抗癌协会大肠癌专业委员会,等.结直肠癌肝转移诊断和综合治疗指南(2016版)[J].中华消化外科杂志,2016,15(8):755-767.
[6]王盛,喻春钊.结直肠癌肝转移的治疗现状[J/CD].中华普通外科学文献(电子版),2017,11(1):51-55.
[7]忠诚,苏冀.结直肠癌肝转移的转化治疗策略[J/CD].中华结直肠疾病电子杂志,2013,2(5):217-220.
[8]Haraldsdottir S,Wu C,Bloomston M,et al.What is the optimal neoadjuvant treatment for liver metastasis?[J].Ther Adv Med Oncol,2013,5(4):221-234.
[9]Yin Z,Liu C,Chen Y,et al.Timing of hepatectomy in resectable synchronous colorectal liver metastases(SCRLM):Simultaneous or delayed?[J].Hepatology,2013,57(6):2346-2357.
[10]杨亮亮,任黎.同时性结肠癌肝转移转化治疗后一期切除原发灶及肝转移灶[J].中华消化外科杂志,2016,15(2):185-190.
[11]Waisberg J,Lvankovics IG.Liver-first approach of colorectal cancer with synchronous hepatic metastases:A reverse strategy[J].World J Hepatol,2015,7(11):1444-1449.
[12]Rahbari NN,Bork U,Sch?lch S,et al.Metastatic Spread Emerging From Liver Metastases of Colorectal Cancer:Does the Seed Leave the Soil Again?[J].Ann Surg,2016,263(2):345-352.
[13]Wei M,He Y,Wang J,et al.Laparoscopic versus open hepatectomy with or without synchronous colectomy for colorectal liver metastasis:a meta-analysis[J].PLoS One,2014,9(1):e87461.
[14]戴朝六,徐锋.个体化治疗直肠癌同时性肝转移[J].中华消化外科杂志,2014,13(3):175-179.