细胞衰老在细胞生物学方面的研究进展
摘要
细胞衰老是一种抵制外界压力刺激的细胞保护性机制,可以促进受损的细胞的清除。细胞衰老的原因及诱发细胞衰老的条件,仍是当今科学研究的重点。探求细胞衰老对细胞生物学,以及其他科学研究具有重要意义。
引文
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[4]Wang X,Guo Z,Ding Z,et al.Endothelin-1 upregulation mediates aging-related cardiac fibrosis[J].J Mol Cell Cardiol,2015,80:101-09.
[5]Zhang X,Han X,Yin L,et al.Potent effects of dioscin against liver fibrosis[J].Sci Rep,2015,5:9713.
[6]Dimri GP,Lee X,Basile G,et al.A biomarker that identifies senescent human cells in culture and in aging skin in vivo[J].ProcNatl Acad Sci USA,1995,92(20):9363-7.
[7]Kosar M,Bartkova J,Hubackova S,et al.Senescence-associated heterochromatin foci are dispensable for cellular senescence,occur in a cell type-and insult-dependent manner and follow expression of p16(ink4a)[J].Cell Cycle,2011,10(3):457-68.
[8]Young AR,Narita M,Ferreira M,et al.Autophagy mediates the mitotic senescence transition[J].Genes Dev,2009,23(7):798-803.
[9]Nakanuma Y,S asaki M,Harada K.Autophagy and senescence in fibrosing cholangiopathies[J].J Hepatol,2015,62(4):934-45.