超声造影评价不稳定型心绞痛患者颈动脉硬化斑块厚度与斑块内新生血管密度的相关性
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摘要
目的探讨不稳定型心绞痛患者颈动脉粥样硬化脉斑块厚度与超声造影评价颈动脉斑块内新生血管密度的相关性。方法对71例不稳定型心绞痛患者颈动脉粥样硬化患者的106个斑块行超声造影检查。结果颈动脉不同厚度斑块内新生血管密度分级与斑块的厚度呈正相关(rs=0.537)。结论不稳定型心绞痛患者颈动脉不同厚度的低回声、以低回声为主的混合回声斑块内新生血管密度与斑块厚度呈正相关。
Objective To explore the correlation between carotid plaque thickness and neovascularization of plaques in patients with unstable angina. Methods A total of 102 plaques on 71 patients with carotid atherosclerosis were examined by contrast-enhanced ultrasonography(CEUS). Results There was a positive correlation between carotid neovascularization of plaques and plaque thickness(rs=0.537). Conclusion In patients with unstable angina, for carotid low-echo and hypoechoic mixed echo plaques in different thickness,there is a positive correlation between the density of neovascularization and the thickness.
Objective To explore the correlation between carotid plaque thickness and neovascularization of plaques in patients with unstable angina. Methods A total of 102 plaques on 71 patients with carotid atherosclerosis were examined by contrast-enhanced ultrasonography(CEUS). Results There was a positive correlation between carotid neovascularization of plaques and plaque thickness(rs=0.537). Conclusion In patients with unstable angina, for carotid low-echo and hypoechoic mixed echo plaques in different thickness,there is a positive correlation between the density of neovascularization and the thickness.
引文
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[10]魏小雨,杨力,王雪,等.SMI和超声造影在颈动脉斑块内新生血管的比较分析[J].中国超声医学杂志,2018,34(4):307-309.
[11]Koole D,Heyligers J,Moll FL,et al.Intraplaque neovascular-ization and hemorrhage:markers for cardio vascular risk stratification and therapeutic monitoring[J].J Cardiovasc Med,2012,13(5):635-639.
[12]史素君,勇强,刘欣,等.颈动脉斑块易损性对冠状动脉狭窄严重程度的预测价值[J].中国超声医学杂志,2017,33(5):406-408.
[13]Partovi S,Loebe M,Aschwanden M,et al.Contrast-enhanced ultrasound for assessing carotid atherosclerotic plaque lesion[J].AJR Am J Roentgenol,2012,198(1):13-19.
[14]Iezzi R,Petrone G,Ferrante A,et al.The role of contrast-enhanced ultrasound(CEUS)in visualizing atherosclerotic carotid plaque vulnerability:Which injection protocol?Which scanning technique?[J].Eur J Radiol,2015,84(5):865-871.
[15]郭玉平,张春梅,吴向菊,等.超声微血流成像技术检测颈动脉斑块内新生血管的价值[J].中国临床医学影像杂志,2016,27(6):400-402.
[16]蒋彦彦,朱建平,孙立.超声造影评价颈动脉斑块内新生血管的应用研究[J].中国超声医学杂志,2016,32(9):776-779.C
[2]张凤秀,潘明康,陈玲丽,等.稳定型与不稳定型心绞痛患者颈动脉硬化斑块新生血管超声造影特点的对比研究[J].心肺血管病杂志,2017,36(1),47-50.
[3]李超伦,王文平,何婉媛,等.不同回声类型颈动脉斑块超声造影增强强度的分析[J].中华医学超声杂志(电子版),2012,9(12):1052-1056.
[4]陈霞.超声造影结合时间-强度曲线评价颈动脉斑块与冠心病的相关性[J].中医临床研究,2017,9(13):138-139.
[5]杨璐,王文.超声造影评价颈动脉斑块类型与斑块内新生血管关系[J].中国医学影像技术,2015,31(1):28-31.
[6]张凤秀,潘明康,赵君,等.心绞痛患者颈动脉粥样硬化斑块内新生微血管超声造影特征的临床研究[J].微循环学杂志,2017,27(1):43-46.
[7]Zhu Y,Deng YB,Liu YN,et al.Use of carotid plaque neovascularization at contrast-enhanced US to predict coronary events in patients with coronary artery disease[J].Radiology,2013,268(1):54-60.
[8]葛均波,徐永健.内科学[M].第七版.北京:人民卫生出版社,2016:236-237.
[9]勇强,张蕾,王丽娟,等.颈动脉斑块风险等级的超声评价[J].血管与腔内血管外科杂志,2016,2(4):278-281.
[10]魏小雨,杨力,王雪,等.SMI和超声造影在颈动脉斑块内新生血管的比较分析[J].中国超声医学杂志,2018,34(4):307-309.
[11]Koole D,Heyligers J,Moll FL,et al.Intraplaque neovascular-ization and hemorrhage:markers for cardio vascular risk stratification and therapeutic monitoring[J].J Cardiovasc Med,2012,13(5):635-639.
[12]史素君,勇强,刘欣,等.颈动脉斑块易损性对冠状动脉狭窄严重程度的预测价值[J].中国超声医学杂志,2017,33(5):406-408.
[13]Partovi S,Loebe M,Aschwanden M,et al.Contrast-enhanced ultrasound for assessing carotid atherosclerotic plaque lesion[J].AJR Am J Roentgenol,2012,198(1):13-19.
[14]Iezzi R,Petrone G,Ferrante A,et al.The role of contrast-enhanced ultrasound(CEUS)in visualizing atherosclerotic carotid plaque vulnerability:Which injection protocol?Which scanning technique?[J].Eur J Radiol,2015,84(5):865-871.
[15]郭玉平,张春梅,吴向菊,等.超声微血流成像技术检测颈动脉斑块内新生血管的价值[J].中国临床医学影像杂志,2016,27(6):400-402.
[16]蒋彦彦,朱建平,孙立.超声造影评价颈动脉斑块内新生血管的应用研究[J].中国超声医学杂志,2016,32(9):776-779.C