正畸微种植体支抗对错(牙合)畸形影响分析
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摘要
目的研究正畸微种植体支抗对错(牙合)畸形的影响。方法选择错(牙合)畸形患者作为本次研究对象,并采用"电脑随机法"将100例错(牙合)畸形患者进行分组,主要包括两组,其中观察组实施正畸微种植体支抗治疗;对照组实施传统治疗,分析两组炎症因子水平、牙周细胞MMP-2、MMP-9表达、矫治时间。结果观察组错(牙合)畸形患者TNF-α(165.98±1.24)μg/L、 IL-1β(125.04±1.35)μg/L、IL-6(61.29±1.82)pg/mL水平均低于对照组,P <0.05。观察组错(牙合)畸形患者MMP-2、MMP-9表达较对照组指标更有优势,P <0.05。观察组错(牙合)畸形患者矫治时间(14.24±1.04)个月,短于对照组,差异有统计学意义,P <0.05。结论正畸微种植体支抗在错(牙合)畸形中具有较高应用价值,能够使其牙周炎微环境得到改善,促进牙周组织尽快修复,值得研究。
Objective To study the effect of orthodontic micro-implant anchorage on malocclusion. Methods Patients with malocclusion were selected as the study subjects, and 100 patients with malocclusion were divided into two groups. The observation group was treated with orthodontic micro-implant anchorage. The control group was treated with traditional treatment, the levels of inflammatory factors,the expression of MMP-2 and MMP-9 in periodontal cells, and the time of treatment were analyzed. Results The levels of TNF-α(165.98 ± 1.24) μg/L, IL-1 beta(125.04 ± 1.35) μg/L and IL-6(61.29± 1.82) pg/mL in the observation group were lower than those in the control group, P < 0.05. The expression of MMP-2 and MMP-9 in the observation group was better than that in the control group, P < 0.05.The orthodontic time of malocclusion patients in the observation group was(14.24 ± 1.04) months, which was shorter than that in the control group, P < 0.05. Conclusion Orthodontic micro-implant anchorage has high application value in malocclusion, which can improve the microenvironment of periodontitis and promote the repair of periodontal tissue as soon as possible.
Objective To study the effect of orthodontic micro-implant anchorage on malocclusion. Methods Patients with malocclusion were selected as the study subjects, and 100 patients with malocclusion were divided into two groups. The observation group was treated with orthodontic micro-implant anchorage. The control group was treated with traditional treatment, the levels of inflammatory factors,the expression of MMP-2 and MMP-9 in periodontal cells, and the time of treatment were analyzed. Results The levels of TNF-α(165.98 ± 1.24) μg/L, IL-1 beta(125.04 ± 1.35) μg/L and IL-6(61.29± 1.82) pg/mL in the observation group were lower than those in the control group, P < 0.05. The expression of MMP-2 and MMP-9 in the observation group was better than that in the control group, P < 0.05.The orthodontic time of malocclusion patients in the observation group was(14.24 ± 1.04) months, which was shorter than that in the control group, P < 0.05. Conclusion Orthodontic micro-implant anchorage has high application value in malocclusion, which can improve the microenvironment of periodontitis and promote the repair of periodontal tissue as soon as possible.
引文
[1]彭秋实,李沙.正畸微种植体支抗对错牙合畸形患者牙周炎性微环境的影响[J].山东医药,2017,57(24):89-91.
[2]钱毅,周华杰,吴建华.微种植体和传统支抗治疗错(牙合)畸形的效果比较[J].上海口腔医学,2017,26(3):339-342.
[3]陈敏,宣桂红.微型种植体支抗对青少年口腔正畸疗效及依从性的影响[J].中国现代医学杂志,2018,28(8):94-97.
[4]田国永,鹿国英,吕志军.微钛钉种植体支抗和传统支抗矫正上颌前突畸形的疗效比较[J].海南医学,2017,28(15):2448-2450.
[5]范少轻,周彦恒.种植体支抗整体远中移动下颌牙列治疗骨性Ⅲ类错牙合的疗效评价[J].北京大学学报:医学版,2017,49(3):531-539.
[6]吴斯媛,宗丽,郑骏明,等.微种植体支抗不同植入部位对患者牙科焦虑症和疼痛的影响[J].广东医学,2017,38(12):1885-1888.
[7]熊亚芳,朱妮蔓,杨芳.不同正畸治疗措施错(牙合)畸形患者龈沟液MMP-2、TIMP-2水平的影响分析[J].口腔医学研究,2018,34(5):544-547.
[8]Farjo N,Turpin DL,Coley RY,et al.Characteristics and fate of orthodontic articles submitted for publication:An exploratory study of the American Journal of Orthodontics and Dentofacial Orthopedics[J].American Journal of Orthodontics and Dentofacial Orthopedics,2015,147(6):680-690.
[9]薛美荣,武秀萍.不同植入角度下骨皮质厚度对微种植钉稳定性的影响[J].中国药物与临床,2017,17(5):669-671.
[10]张清华,范红.3种应用于正畸支抗的金属材料的细胞毒性和遗传毒性检测[J].实用口腔医学杂志,2017,33(2):179-183.
[11]陈敏,阮土耿.正畸治疗对错颌畸形儿童口腔健康相关生活质量的影响[J].中国妇幼保健,2017,32(21):5352-5354.
[12]武秀萍,HEE MoonKyung,李冰,等.“微种植体支抗双槽沟舌侧托槽”矫治系统前牙移动的磁感应Typodont实验[J].中国组织工程研究,2017,21(22):3525-3530.
[13]徐建华,王玲,刘怀勤,等.正畸联合正颌治疗对骨性Ⅲ类错颌畸形伴偏颌患者侧貌改善及咬合功能的影响[J].河北医科大学学报,2017,38(7):801-804.
[2]钱毅,周华杰,吴建华.微种植体和传统支抗治疗错(牙合)畸形的效果比较[J].上海口腔医学,2017,26(3):339-342.
[3]陈敏,宣桂红.微型种植体支抗对青少年口腔正畸疗效及依从性的影响[J].中国现代医学杂志,2018,28(8):94-97.
[4]田国永,鹿国英,吕志军.微钛钉种植体支抗和传统支抗矫正上颌前突畸形的疗效比较[J].海南医学,2017,28(15):2448-2450.
[5]范少轻,周彦恒.种植体支抗整体远中移动下颌牙列治疗骨性Ⅲ类错牙合的疗效评价[J].北京大学学报:医学版,2017,49(3):531-539.
[6]吴斯媛,宗丽,郑骏明,等.微种植体支抗不同植入部位对患者牙科焦虑症和疼痛的影响[J].广东医学,2017,38(12):1885-1888.
[7]熊亚芳,朱妮蔓,杨芳.不同正畸治疗措施错(牙合)畸形患者龈沟液MMP-2、TIMP-2水平的影响分析[J].口腔医学研究,2018,34(5):544-547.
[8]Farjo N,Turpin DL,Coley RY,et al.Characteristics and fate of orthodontic articles submitted for publication:An exploratory study of the American Journal of Orthodontics and Dentofacial Orthopedics[J].American Journal of Orthodontics and Dentofacial Orthopedics,2015,147(6):680-690.
[9]薛美荣,武秀萍.不同植入角度下骨皮质厚度对微种植钉稳定性的影响[J].中国药物与临床,2017,17(5):669-671.
[10]张清华,范红.3种应用于正畸支抗的金属材料的细胞毒性和遗传毒性检测[J].实用口腔医学杂志,2017,33(2):179-183.
[11]陈敏,阮土耿.正畸治疗对错颌畸形儿童口腔健康相关生活质量的影响[J].中国妇幼保健,2017,32(21):5352-5354.
[12]武秀萍,HEE MoonKyung,李冰,等.“微种植体支抗双槽沟舌侧托槽”矫治系统前牙移动的磁感应Typodont实验[J].中国组织工程研究,2017,21(22):3525-3530.
[13]徐建华,王玲,刘怀勤,等.正畸联合正颌治疗对骨性Ⅲ类错颌畸形伴偏颌患者侧貌改善及咬合功能的影响[J].河北医科大学学报,2017,38(7):801-804.