右美托咪定对小儿扁桃体腺样体等离子切除术后躁动的影响
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摘要
目的探讨右美托咪定对小儿扁桃体腺样体等离子切除术后躁动的影响。方法选择2018年1—7月在安徽医科大学第二附属医院行扁桃体腺样体等离子切除术的62例患儿,随机分为观察组和对照组,每组31例。对照组采用丙泊酚维持麻醉,观察组采用丙泊酚+右美托咪定维持麻醉。比较两组患儿的麻醉药物使用量、苏醒后躁动评分、视觉模拟评分法(visual analoguescale,VAS)疼痛评分及术后躁动发生率。结果观察组患儿麻醉药物使用量[(68.5±9.9)mg]、苏醒后躁动评分[(1.3±0.5)分]、VAS疼痛评分[(3.3±1.4)分]均明显低于对照组[分别为(88.6±9.5)mg、(2.7±0.7)分、(4.1±1.5)分],差异有显著性(P<0.05)。观察组术后躁动发生率(3.23%)明显低于对照组(16.13%),差异有显著性(P<0.05)。结论小儿扁桃体腺样体等离子切除术中应用右美托咪定可预防患儿术后躁动,提高手术治疗的安全性。
Objective To explore the effect of dexmedetomidine on restlessness in children after tonsillar adenoid plasma resection. Method From Jan 2018 to July 2018, 62 children with tonsillar adenoid plasma resection were observed and analyzed in our hospital. Propofol was used in the control group and dexmedetomidine was used in the study group. Result The use of anesthetic drugs, post awakening agitation score and VAS pain score in the study group were all lower than those in the control group, and the difference was signi? cant(P<0.05).The incidence of restlessness in the study group was signi? cantly lower than that in the control group, and the difference between the groups was signi? cant(P<0.05). Conclusion Dexmedetomidine can prevent restlessness and improve the safety and reliability of surgical treatment in children with tonsil adenoid plasma resection.
Objective To explore the effect of dexmedetomidine on restlessness in children after tonsillar adenoid plasma resection. Method From Jan 2018 to July 2018, 62 children with tonsillar adenoid plasma resection were observed and analyzed in our hospital. Propofol was used in the control group and dexmedetomidine was used in the study group. Result The use of anesthetic drugs, post awakening agitation score and VAS pain score in the study group were all lower than those in the control group, and the difference was signi? cant(P<0.05).The incidence of restlessness in the study group was signi? cantly lower than that in the control group, and the difference between the groups was signi? cant(P<0.05). Conclusion Dexmedetomidine can prevent restlessness and improve the safety and reliability of surgical treatment in children with tonsil adenoid plasma resection.
引文
[1]李世杰.探讨不同剂量右美托咪定对小儿七氟烷麻醉术后急性躁动及睁眼时间的影响[J].中国现代药物应用,2015,9(24):126-127.
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[9]张高娇,张归帆,蒋学斌,等.右美托咪定术中输注对扁桃体腺样体切除患儿血流动力学的影响[J].浙江临床医学,2015,16(2):308-310.
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[11]罗彬菱,胡兰,汤磊,等.右美托咪定用于小儿先天性心脏病术后镇静镇痛的疗效和安全性研究[J].儿科药学杂志,2014,20(1):11-13.
[12]包小红,叶宏武,陈莉,等.右美托咪定对小儿扁桃体合并腺样体手术全麻苏醒期躁动的影响[J].安徽医药,2014,18(5):944-946.
[13]任长和,张杨,吴刚明,等.右美托咪啶预防眼科患儿全身麻醉苏醒期躁动的研究[J].重庆医学,2014,43(17):2201-2204.
[14]舒礼佩,张光英.小剂量右旋美托咪定对鼾症患儿七氟醚麻醉苏醒期的影响[J].广西医学,2014,36(7):895-898.
[2]洪李萍.右美托咪定预防小儿扁桃体摘除术苏醒期躁动[J].中国现代医生,2015,53(34):114-116,127.
[3]Nishizawa T,Suzuki H,Sagara S,et al.Dexmedetomidine versus midazolam for gastrointestinal endoscopy:a meta-analysis[J].Dig Endosc,2015,27(1):8-15.
[4]周述芝,宋丽,刘雪茹,等.右美托咪定对全身麻醉苏醒期躁动及术后恢复质量的影响[J].重庆医学,2014,43(36):4939-4941.
[5]Fujiwara A,Komasawa N,Minami T.Pectoral nerves(PECS)and intercostal nerve block for cardiac resynchronization therapy device implantation[J].Springerplus,2014,3:409.
[6]易声华,陈忠华,胡双燕,等.术前应用右美托咪定复合氟比洛芬酯对小儿扁桃体摘除术后躁动的影响[J].中国临床药理学与治疗学,2013,18(9):1044-1048.
[7]谭红保,徐军美,赵倩,等.右美托咪定对老年患者胃肠道手术术后早期认知功能障碍的影响[J].中国医刊,2018,53(5):60-63.
[8]邓微菲,王颖,张洲,等.右美托咪定对扁桃体、腺样体摘除术患儿麻醉及术后镇痛的影响[J].重庆医学,2014,43(18):2297-2299.
[9]张高娇,张归帆,蒋学斌,等.右美托咪定术中输注对扁桃体腺样体切除患儿血流动力学的影响[J].浙江临床医学,2015,16(2):308-310.
[10]庞健.鼻内镜下扁桃体腺样体联合摘除术治疗小儿阻塞性睡眠呼吸暂停通气综合征79例分析[J].中国药物经济学,2014,9(1):273-274.
[11]罗彬菱,胡兰,汤磊,等.右美托咪定用于小儿先天性心脏病术后镇静镇痛的疗效和安全性研究[J].儿科药学杂志,2014,20(1):11-13.
[12]包小红,叶宏武,陈莉,等.右美托咪定对小儿扁桃体合并腺样体手术全麻苏醒期躁动的影响[J].安徽医药,2014,18(5):944-946.
[13]任长和,张杨,吴刚明,等.右美托咪啶预防眼科患儿全身麻醉苏醒期躁动的研究[J].重庆医学,2014,43(17):2201-2204.
[14]舒礼佩,张光英.小剂量右旋美托咪定对鼾症患儿七氟醚麻醉苏醒期的影响[J].广西医学,2014,36(7):895-898.