疣状毛癣菌致母女共患体癣分析
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摘要
母亲上肢出现皮损1年,女儿面部皮损4个月,皮损表现为大小不一的环形红斑,表面覆有鳞屑及少许痂皮,境界清楚,边缘稍隆起。患者家中养牛。两例皮损真菌镜检均可见菌丝,真菌培养均阳性,分离菌株经表型及分子鉴定,两株菌均为疣状毛癣菌,体外药敏试验显示对伊曲康唑及特比萘芬均敏感。2例患者经口服和外用抗真菌药物联合治疗获痊愈。
The lesions located on the mother's up limbs for one year and on daughter's face for 4 months. The lesions characterized by annular erythema. The surface was covered with scales and a little scab with boundary clear and slightly uplifted edge. They had a history of raising cattles. The strains isolated from the patients were identified as Trichophyton verrucosum based on the morphological, growth tests and molecular methods. In vitro drug susceptibility test showed Trichophyton verrucosum was sensitive to itraconazole or terbinafin. The patients were cured. wth oral and topical antifungal drugs.
The lesions located on the mother's up limbs for one year and on daughter's face for 4 months. The lesions characterized by annular erythema. The surface was covered with scales and a little scab with boundary clear and slightly uplifted edge. They had a history of raising cattles. The strains isolated from the patients were identified as Trichophyton verrucosum based on the morphological, growth tests and molecular methods. In vitro drug susceptibility test showed Trichophyton verrucosum was sensitive to itraconazole or terbinafin. The patients were cured. wth oral and topical antifungal drugs.
引文
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[3] 马颖,尤德渊.某牧场人畜共患皮肤癣菌病病原菌调查[J].中国麻风皮肤病杂志,2012,28(7):467-469.
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[7] Gülgün Y,Ebru T,Aydan Y,et al.In vitro activities of antifungal drugs against dermatophytes isolated in Tokat,Turkey[J].Int J Dermatol,2013,52(12):1557-1560.
[8] Courtellemont L,Chevrier S,Degeilh B,et al.Epidemiology of Trichophyton verrucosum infection in Rennes University Hospital,France:A 12-year retrospective study[J].Med Mycol,2017 55(7):720-724.
[9] Cvelbara D,?ista V,Kobal K,et al.Steroid toxicity and detoxification in ascomycetous fungi[J].Chemico-Biological Interactions,2013,202(1-3):243-258.
[2] Placzek M,Van den Heuvel ME,Flaig MJ,et al.Perniosis-like tinea corporis caused by Trichophyton verrucosum in cold-exposed individuals[J].Mycoses,2010,49(6):476-479.
[3] 马颖,尤德渊.某牧场人畜共患皮肤癣菌病病原菌调查[J].中国麻风皮肤病杂志,2012,28(7):467-469.
[4] deHoog GS,Guarro J,Gené J,et al.Atlas of Clinical Fungi:The ultimate benchtool for diagnostics[M].version 4.0(July 2014).
[5] Kavala M,Sudogan S,Beyhan S,et al.Unusual presentation ofTrichophytonverrucosumcausing hydronephrosis and joint contractures[J].Int J Dermatol,2010,49(1):102-103.
[6] Yamada A,Noguchi H,Sakae H,et al.Tinea faciei caused by Trichophyton verrucosum in a 20-month-old female:Case report and summary of reported cases in Japan[J].J Dermatol,2012,39(7):667-669.
[7] Gülgün Y,Ebru T,Aydan Y,et al.In vitro activities of antifungal drugs against dermatophytes isolated in Tokat,Turkey[J].Int J Dermatol,2013,52(12):1557-1560.
[8] Courtellemont L,Chevrier S,Degeilh B,et al.Epidemiology of Trichophyton verrucosum infection in Rennes University Hospital,France:A 12-year retrospective study[J].Med Mycol,2017 55(7):720-724.
[9] Cvelbara D,?ista V,Kobal K,et al.Steroid toxicity and detoxification in ascomycetous fungi[J].Chemico-Biological Interactions,2013,202(1-3):243-258.