中药复方治疗冠心病心绞痛的临床疗效分析
|
摘要
目的:研究中药复方治疗冠心病心绞痛的临床疗效。方法:选取2015年8月-2016年8月我院90例冠心病心绞痛患者随机分成A、B两组,A组给予常规西药治疗,B组在A组基础上加用益气活血方辅助治疗。在治疗前后,对两组患者疗效评价,并检测患者的血常规、肝肾功能、血脂,观察用药期间不良反应的发生情况。结果:A组的总有效率为62.22%,B组总有效率为91.11%,B组总有效率明显高于A组,差异有统计学意义(P<0.05);经过治疗后,A、B两组的TC及LDL均明显下降,差异有统计学意义(P<0.05);与A组相比,B组治疗后LDL更低,差异有统计学意义(P<0.05);A、B两组治疗前后PLT、ALT及Cr均无明显变化,差异无统计学意义(P>0.05),两组在治疗期间均未发生药物不良反应。结论:中药复方治疗冠心病心绞痛能够有效控制临床症状,降低血脂,且安全无明显不良反应,可在临床推广使用。
Objective: To study the clinical effect of Chinese medicine compound on angina. Methods: 90 patients with coronary heart disease treated in our hospital from August 2015 to August 2016 were randomly divided into two groups, Group A and Group B, who were treated with conventional western medicine and the supplemental treatment of Yiqi Huoxue Formula respectively. Before and after treatment, the treatment effect of two groups was evaluated, and blood routine, liver and kidney function, blood lipids were examined, and the adverse reactions were observed. Results: The total efficiency of group A was 62.22%, and the total efficiency of group B was 91.11%, group B was significantly more efficient than group A, and the difference was statistically significant(P<0.05). After treatment, the TC and LDL of both groups decreased significantly, and the difference was statistically significant(P< 0.05). Compared with group A, group B had lower LDL and the difference was of statistical significance(P<0.05). There was no significant change in PLT, ALT and Cr before and after treatment in both Group A and Group B, and the difference was not statistically significant(P>0.05), and neither group had adverse reactions of medicine during the treatment. Conclusion: Chinese medicine compound treatment could effectively control the clinical symptoms and reduce blood fat in treating coronary heart disease angina pectoris; it had no obvious adverse reaction and was of high safety, which could be used widely in clinical practice.
Objective: To study the clinical effect of Chinese medicine compound on angina. Methods: 90 patients with coronary heart disease treated in our hospital from August 2015 to August 2016 were randomly divided into two groups, Group A and Group B, who were treated with conventional western medicine and the supplemental treatment of Yiqi Huoxue Formula respectively. Before and after treatment, the treatment effect of two groups was evaluated, and blood routine, liver and kidney function, blood lipids were examined, and the adverse reactions were observed. Results: The total efficiency of group A was 62.22%, and the total efficiency of group B was 91.11%, group B was significantly more efficient than group A, and the difference was statistically significant(P<0.05). After treatment, the TC and LDL of both groups decreased significantly, and the difference was statistically significant(P< 0.05). Compared with group A, group B had lower LDL and the difference was of statistical significance(P<0.05). There was no significant change in PLT, ALT and Cr before and after treatment in both Group A and Group B, and the difference was not statistically significant(P>0.05), and neither group had adverse reactions of medicine during the treatment. Conclusion: Chinese medicine compound treatment could effectively control the clinical symptoms and reduce blood fat in treating coronary heart disease angina pectoris; it had no obvious adverse reaction and was of high safety, which could be used widely in clinical practice.
引文
[1]王波,王临池,赵翼洪,等.2009-2013年苏州20岁及以上居民冠心病发病率变化趋势及类型分析[J].中国全科医学,2015,18(24):2952-2956.
[2]毕颖斐,毛静远,王贤良,等.中医药防治冠心病临床优势及有关疗效评价的思考[J].中医杂志,2015,56(05):437-440.
[3]岳翔.炙甘草汤治疗冠心病心律失常的效果评估报道分析[J].中医临床研究,2016,8(26):60-61.
[4]刘珂,邱炳勋,邹利.黄芪及其有效成分对内皮细胞及其连接的保护作用及机制研究进展[J].中草药,2016,47(21):3912-3917.
[5]徐萌.中医补气活血法治疗冠心病对临床症状、心肌缺血的改善作用[J].中医临床研究,2014,6(24):39-41.
[2]毕颖斐,毛静远,王贤良,等.中医药防治冠心病临床优势及有关疗效评价的思考[J].中医杂志,2015,56(05):437-440.
[3]岳翔.炙甘草汤治疗冠心病心律失常的效果评估报道分析[J].中医临床研究,2016,8(26):60-61.
[4]刘珂,邱炳勋,邹利.黄芪及其有效成分对内皮细胞及其连接的保护作用及机制研究进展[J].中草药,2016,47(21):3912-3917.
[5]徐萌.中医补气活血法治疗冠心病对临床症状、心肌缺血的改善作用[J].中医临床研究,2014,6(24):39-41.