数字光导PET-CT质量控制方法探讨与结果分析
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摘要
目的:探讨数字光导正电子发射计算机断层显像(PET)-CT常规质量控制方法,为PET-CT设备验收和质量控制提供技术支持。方法:依据国家标准GB18988-1、美国国家电气制造商协会(NEMA)NU2-2007,结合PET-CT设备的无源及有源质量控制方法,回顾分析2016年11月至2018年7月设备机房环境温度和相对湿度,设备工作电压、计数率、晶体位置查找表(LUT)漂移、能量漂移与飞行时间(TOF)漂移等质量控制数据,分析评价质量控制通过率,建立质量控制体系。结果:2年数据显示PET-CT设备的性能良好,质量控制总通过率为94.5%,温度、电压、最高计数率、晶体位置查找表(LUT)漂移与TOF漂移均保持在正常值范围内,通过率为100%。相对湿度浮动区间为3.0%～66.3%,均值为25.6%,标准差为11.25%;最低计数率浮动区间为71.9～111.2,均值为105.1,标准差为4.55;能量漂移均值为2.03;PET-CT设备机房湿度是影响质量控制通过率的主要因素。结论:建立的PET-CT设备质量控制测试及分析方法有效,可为PET-CT设备验收和质量控制提供技术依据。
Objective: To investigate the routine quality control(QC) methods of positron emission tomography CT(PET-CT) that adopted digitally light guide so as to provide technical support for equipment acceptance and quality control. Methods: According to the national standard(GB18988-1) and NU2-2007 of national electrical manufacturers association(NEMA), and combined with quality control method without radioactive source and with radioactive source of PET-CT equipment to retrospectively analyze series of quality control data included environmental temperature and humidity of equipment machine room during the term of November 2016 to July 2018, working voltage, counting rate, look-up-table(LUT) drifting of crystal position, energy drifting and time of flight(TOF) drifting of equipment, and to analyze and evaluate passing rate of quality control. Results: The performance of PET-CT instrument has been good in the past 2 years, and the total passing rate of quality control was 94.5%. And the temperature, voltage, the maximum count rate, LUT drifting and FOF drifting of instrument were kept within the normal range, and the passing rate was 100%. The floating zone of humidity was from 3.0% to 66.3%, and its mean and standard deviation were 25.55% and 11.25%, respectively. And the floating zone of lowest counting rate was from 71.9 to 111.2, and its mean and standard deviation were 105.09 and 4.55, respectively. And the mean of energy drifting was 2.03. Besides, the humidity of machine room of PET-CT equipment was the main factor that affected passing rate of quality control. Conclusion: The test and analysis methods of quality control of PET-CT equipment that are used in this study are scientific and effective. And they can provide technical support for acceptance and quality control of PET-CT equipment.
Objective: To investigate the routine quality control(QC) methods of positron emission tomography CT(PET-CT) that adopted digitally light guide so as to provide technical support for equipment acceptance and quality control. Methods: According to the national standard(GB18988-1) and NU2-2007 of national electrical manufacturers association(NEMA), and combined with quality control method without radioactive source and with radioactive source of PET-CT equipment to retrospectively analyze series of quality control data included environmental temperature and humidity of equipment machine room during the term of November 2016 to July 2018, working voltage, counting rate, look-up-table(LUT) drifting of crystal position, energy drifting and time of flight(TOF) drifting of equipment, and to analyze and evaluate passing rate of quality control. Results: The performance of PET-CT instrument has been good in the past 2 years, and the total passing rate of quality control was 94.5%. And the temperature, voltage, the maximum count rate, LUT drifting and FOF drifting of instrument were kept within the normal range, and the passing rate was 100%. The floating zone of humidity was from 3.0% to 66.3%, and its mean and standard deviation were 25.55% and 11.25%, respectively. And the floating zone of lowest counting rate was from 71.9 to 111.2, and its mean and standard deviation were 105.09 and 4.55, respectively. And the mean of energy drifting was 2.03. Besides, the humidity of machine room of PET-CT equipment was the main factor that affected passing rate of quality control. Conclusion: The test and analysis methods of quality control of PET-CT equipment that are used in this study are scientific and effective. And they can provide technical support for acceptance and quality control of PET-CT equipment.
引文
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[16]Minamimoto R,Levin C,Jamali M,et al.Improvements in PET Image Quality in Time of Flight(TOF)Simultaneous PET/MRI[J].Mol Imag Biol,2016,18(5):776-781.
[17]李宁,姚忠强,廖光星,等.双探头SPECT-CT仪常规质量控制方法探讨[J].中国医学装备,2018,15(3):23-26.
[18]Manco L,Tonini E,Barboni A,et al.Quality assurance for PET/CT system:NEMA NU2-2012 protocol on the new Siemens Biograph mCT Flow[J].Physica Medica,2016,32(1):108.
[19]Conti PS,Strauss LG.The applications of PETin clinical oncology[J].J Nucl Med,1991,32(4):623-648.
[2]欧阳习,尹吉林,李小华,等.西门子Biograph系列PET/CT质量控制的实践与应用[J].医疗卫生装备,2010,31(6):109-110.
[3]宋颖,刘辉.应用NEMA标准测试Discovery PET/CT690的性能[J].中国辐射卫生,2016,25(6):724-729.
[4]Quang E,Massey R.AM Quick Scan:a simple but effective daily QC test for PET/CT and SPECT/CT[J].J Nucl Med,2015,56(supplement 3):2510-2510.
[5]刘磊.PET医疗质量评分报告[J].内蒙古医科大学学报,2016,38(3):185-188.
[6]孙涛,韩善清,汪家旺.PET/CT成像原理、优势及临床应用[J].中国医学物理学杂志,2010,5(1):1581-1582.
[7]陈英茂,尹大一,田嘉禾,等.PET图像定量计算中的误差分析[J].中国医学影像学杂志,2001,9(5):352-354.
[8]Meyer GJ,Coenen HH,Waters SL,et al.Quality assurance and quality control of shortlived radiopharmaceuticals for PET[M]//Radiopharmaceuticals for positron emission tomography.Springer Dordrecht,1993:91-150.
[9]李正美,侯坤,石丽婷,等.几种PET系统成像参数的测定[J].中国科技信息,2017(20):40-41.
[10]余冬兰,刘阳萍,易畅,等.PET/CT的PET质量控制[J].中国医疗设备,2015,30(5):125-127.
[11]万良荣,黄钢,孙晓光,等.PET/CT的质量控制和日常维护[J].上海交通大学学报,2005,25(12):1303-1305.
[12]党淑琴,夏振民.PET放射性药物的质量保证和质量控制[J].同位素,2001,14(3~4):241-245.
[13]Morgan TL.Quality Assurance for PET and PET/CT Systems[J].Health Physics,2012,103(6):810-811.
[14]Hoffman EJ,Dahlbom M,Ricci AR,et al.Examination of the Role of Detection Systems in Quantitation and Image Quality in PET[J].IEEETransactions on Nuclear Science,1986,33(1):419-424.
[15]Zeimpekis K,Huellner M,De Galiza Barbosa F,et al.Clinical evaluation of PET image quality as a function of acquisition time in a new TOF-PET/MR compared to TOF-PET/CT-initial results[J].EJNMMI Phys,2015,2(Suppl 1):A76.
[16]Minamimoto R,Levin C,Jamali M,et al.Improvements in PET Image Quality in Time of Flight(TOF)Simultaneous PET/MRI[J].Mol Imag Biol,2016,18(5):776-781.
[17]李宁,姚忠强,廖光星,等.双探头SPECT-CT仪常规质量控制方法探讨[J].中国医学装备,2018,15(3):23-26.
[18]Manco L,Tonini E,Barboni A,et al.Quality assurance for PET/CT system:NEMA NU2-2012 protocol on the new Siemens Biograph mCT Flow[J].Physica Medica,2016,32(1):108.
[19]Conti PS,Strauss LG.The applications of PETin clinical oncology[J].J Nucl Med,1991,32(4):623-648.