灵香草药材质量标准初步研究
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摘要
目的初步建立灵香草的质量标准。方法对样品进行性状和显微鉴别;按2015年版《中国药典(四部)》通则2301杂质检查法、0832水分测定法中烘干法、2302灰分测定法、2201浸出物测定法对样品进行相关检查。结果样品的性状和显微特征明显;杂质为1. 75%～3. 09%,水分为10. 84%～12. 78%,总灰分为5. 69%～7. 26%,酸不溶性灰分为0. 42%～0. 78%,95%乙醇浸出物为13. 06%～17. 05%。结论灵香草药材杂质的质量分数不得过4. 0%,水分不得过15. 0%,总灰分不得过8. 5%,酸不溶性灰分不得过1. 0%,热浸法醇溶性浸出物不得低于8. 0%。所建立的质量标准可一定程度控制灵香草质量。
Objective To establish the quality standard of Lysimachia foenum-graecum. Methods The properties and microscopic identification of the samples were carried out,and the related examinations of samples were carried out according to the impurity test in general rule 2301,the oven drying method in moisture test in general rule 0832,ash determination method in general rule 2302 and extract determination method in general rule 2201 of the Chinese Pharmacopoeia( 2015 edition,volume Ⅳ). Results The properties and microscopic characteristics of the samples were obvious,impurities were 1. 75%-3. 09%,water content was 10. 84%-12. 78%,total ash was 5. 69%-7. 26%,acid-insoluble ash was 0. 42%-0. 78%,95% ethanol extract was 13. 06%-17. 05%. Conclusion In the Lysimachia foenum-graecum,the mass fraction of impurities should not be higher than 4. 0%,the water content should not be higher than 15. 0%,the total ash should not be higher than 8. 5%,the acid-insoluble ash should not be higher than 1. 0%,and the alcohol-soluble extract by hot-dipping method should not be lower than 8. 0%. The established quality standard can control the quality of Lysimachia foenum-graecum to a certain extent.
Objective To establish the quality standard of Lysimachia foenum-graecum. Methods The properties and microscopic identification of the samples were carried out,and the related examinations of samples were carried out according to the impurity test in general rule 2301,the oven drying method in moisture test in general rule 0832,ash determination method in general rule 2302 and extract determination method in general rule 2201 of the Chinese Pharmacopoeia( 2015 edition,volume Ⅳ). Results The properties and microscopic characteristics of the samples were obvious,impurities were 1. 75%-3. 09%,water content was 10. 84%-12. 78%,total ash was 5. 69%-7. 26%,acid-insoluble ash was 0. 42%-0. 78%,95% ethanol extract was 13. 06%-17. 05%. Conclusion In the Lysimachia foenum-graecum,the mass fraction of impurities should not be higher than 4. 0%,the water content should not be higher than 15. 0%,the total ash should not be higher than 8. 5%,the acid-insoluble ash should not be higher than 1. 0%,and the alcohol-soluble extract by hot-dipping method should not be lower than 8. 0%. The established quality standard can control the quality of Lysimachia foenum-graecum to a certain extent.
引文
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[14]闫旭宇,李梦妆,李玲.灵香草总黄酮的提取及对羟自由基的清除效率[J].热带作物学报,2017,38(8):1434-1467.
[2]胡展育,詹云静.灵香草的研究进展[J].安徽农业科学,2012,40(29):14240-14242.
[3]江苏新医学院.中药大辞典:下册[M].上海:上海人民出版社,1977:2470.
[4]杨瑞云,李远,何瑞杰,等.灵香草提取物的抑菌活性研究[J].安徽农业科学,2009,37(7):3035-3036.
[5]郑娜,李远,徐伟峰,等.灵香草乙酸乙酯部分抗菌活性及成分研究[J].时珍国医国药,2015,27(1):60-61.
[6]龚复俊,王有为.广西灵香草挥发油化学成分[J].植物资源与环境学报,2004,13(3):59-61.
[7]莫彬彬,余德顺,李典鹏,等.广西灵香草提取物的化学成分研究及香气评价[J].香料香精化妆品,2003,2(1):5-7.
[8]文永新,李典鹏,莫彬彬.超临界CO2萃取灵香草净油的研究[J].广西科学,2002,9(3):174-175.
[9]张德伟,阳文武,封海霞,等.中药质量检测体系建设的思考与对策[J].中国药业,2016,25(16):4-6.
[10]国家药典委员会.中华人民共和国药典(四部)[M].北京:中国医药科技出版社,2015.
[11]朱凯,毛连山,朱新宝.超临界CO2萃取灵香草精油及其化学成分研究[J].精细化工,2005,22(9):681-684.
[12]袁萍,袁晓.灵香草净油化学成分分析及杀虫活性组分的应用研究[J].武汉植物学研究,2007,25(4):417-420.
[13]刘贤贤,张业,覃文,等.灵香草浸膏及其精油是我抗氧化活性研究[J].食品工业科技,2010,12(31):137-138.
[14]闫旭宇,李梦妆,李玲.灵香草总黄酮的提取及对羟自由基的清除效率[J].热带作物学报,2017,38(8):1434-1467.