摘要
<正>Peripheral nerves act like networks of "wires" that conduct signals fromthebrainandspinalcordtoorgansthroughoutthebody.Damage to these nerves leads to numbness, pain, and weakness that eventually reduces the patient’s quality of life. Fortunately, peripheral nerves have a high regenerative capacity and, in most cases, recover
引文
Bain JR,Mackinnon SE,Hunter DA(1989)Functional evaluation of complete sciatic,peroneal,and posterior tibial nerve lesions in the rat.Plast Reconstr Surg 83:129-138.
Filipe VM,Pereira JE,Costa LM,Mauricio AC,Couto PA,Melo-Pinto P,Varejao AS(2006)Effect of skin movement on the analysis of hindlimb kinematics during treadmill locomotion in rats.J Neurosci Methods153:55-61.
Lee JY,Giusti G,Wang H,Friedrich PF,Bishop AT,Shin AY(2013)Functional evaluation in the rat sciatic nerve defect model:a comparison of the sciatic functional index,ankle angles,and isometric tetanic force.Plast Reconstr Surg 132:1173-1180.
Monte-Raso VV,Barbieri CH,Mazzer N,Yamasita AC,Barbieri G(2008)Is the Sciatic Functional Index always reliable and reproducible?J Neurosci Methods 170:255-261.
Munro CA,Szalai JP,Mackinnon SE,Midha R(1998)Lack of association between outcome measures of nerve regeneration.Muscle Nerve21:1095-1097.
Rui J,Runge MB,Spinner RJ,Yaszemski MJ,Windebank AJ,Wang H(2014)Gait cycle analysis:parameters sensitive for functional evaluation of peripheral nerve recovery in rat hind limbs.Ann Plast Surg 73:405-411.
Sarikcioglu L,Demirel BM,Utuk A(2009)Walking track analysis:an assessment method for functional recovery after sciatic nerve injury in the rat.Folia Morphol 68:1-7.
Tajino J,Ito A,Tanima M,Yamaguchi S,Iijima H,Nakahata A,Kiyan W,Aoyama T,Kuroki H(2018)Three-dimensional motion analysis for comprehensive understanding of gait characteristics after sciatic nerve lesion in rodents.Sci Rep 8:13585.
Wang T,Ito A,Aoyama T,Nakahara R,Nakahata A,Ji X,Zhang J,Kawai H,Kuroki H(2018)Functional evaluation outcomes correlate with histomorphometric changes in the rat sciatic nerve crush injury model:A comparison between sciatic functional index and kinematic analysis.PLoS One 13:e0208985.
Wood MD,Kemp SW,Weber C,Borschel GH,Gordon T(2011)Outcome measures of peripheral nerve regeneration.Ann Anat 193:321-333.
Yang M,Rawson JL,Zhang EW,Arnold PB,Lineaweaver W,Zhang F(2011)Comparisons of outcomes from repair of median nerve and ulnar nerve defect with nerve graft and tubulization:a meta-analysis.J Reconstr Microsurg 27:451-460.