CyclinD1阴性的消化道套细胞淋巴瘤1例
摘要
套细胞淋巴瘤(Mantle cell lymphoma,MCL)是一种小B细胞非霍奇金淋巴瘤,因其肿瘤细胞在淋巴节内呈套区生长模式及伴有染色体t (11; 14)(q13; q32)异常而被世界卫生组织(WHO)造血与淋巴组织分类归为一种独立的疾病。MCL发病率占非霍奇金淋巴瘤(non-Hodgkin lymphoma,NHL)的6%,北美年发病率1/10万~([1]),西欧年发病率(1-2)/10万~([2])。大部分MCL的临床表现早期多不典型,患者确诊时多已呈弥散性病变,处于Ⅲ-Ⅳ期。
引文
[1]Naresh KN,Aqarwal B,Vathwani BN,et al.Use of the World Health Organization(WHO)classification of non-Hodgkin's lymphoma in Mumbai,India:a review of 200 consecutive cases by a panel of five expert hematopathologists[J].Leuk Lymphma,2004,45(8):1569-1577.
[2]Dreyling M,Geisler C,Hermine O,et al.Newly diagnosed and relapsed mantle cell lymphoma:ESMO clinical practice guidelines for diagnosis,treatment and follow-up[J].Ann Oncol,2014,25(3):iii83-92.
[3]Ruskoné-Fourmestraux A,Audouin J.Primary gastrointestinal tract mantle cell lymphoma as multiple lymphomatouspolyposis[J].Best Pract Res Clin Gastroenterol,2010,24(1):35-42.
[4]Matutes E,Parry-jone N,Brito V,et al.The leukemic presentation of mantle-cell lymphomadisease features and prognostic factors in 58 patients[J].Leuk lymphoma,2004,45(10):2007-2015.
[5]Romaguera JE,Medeiros LJ,Hagemeister FB,et al.Frequency of gastrointestinal involvement and its clinical significance in mantle cell lymphoma[J].Cancer,2003,97:586-591.
[6]何鸿鸣,杨榆,周衍,等.41例套细胞淋巴瘤患者临床特征及预后分析[J].中国癌症杂志,2011,21(10):789-793.
[7]杨晶晶,闫志凌,徐开林,等.套细胞淋巴瘤中SOX11差异性表达的研究进展[J].白血病:淋巴瘤,2018,27(5):308-311.
[8]He JX,Xi YF,Su LP,et al.Association of SOX11 gene expression with clinical features and prognosis of mantle cell lymphoma[J].Eur Rev Med Pharmacol Sci,2018,22(9):2556-2563.
[9]Beekman R,Amador V,Campo E.SOX11,a key oncogenic factor in mantle cell lymphoma[J].Curr Opin Hematol,2018,25(4):299-306.
[2]Dreyling M,Geisler C,Hermine O,et al.Newly diagnosed and relapsed mantle cell lymphoma:ESMO clinical practice guidelines for diagnosis,treatment and follow-up[J].Ann Oncol,2014,25(3):iii83-92.
[3]Ruskoné-Fourmestraux A,Audouin J.Primary gastrointestinal tract mantle cell lymphoma as multiple lymphomatouspolyposis[J].Best Pract Res Clin Gastroenterol,2010,24(1):35-42.
[4]Matutes E,Parry-jone N,Brito V,et al.The leukemic presentation of mantle-cell lymphomadisease features and prognostic factors in 58 patients[J].Leuk lymphoma,2004,45(10):2007-2015.
[5]Romaguera JE,Medeiros LJ,Hagemeister FB,et al.Frequency of gastrointestinal involvement and its clinical significance in mantle cell lymphoma[J].Cancer,2003,97:586-591.
[6]何鸿鸣,杨榆,周衍,等.41例套细胞淋巴瘤患者临床特征及预后分析[J].中国癌症杂志,2011,21(10):789-793.
[7]杨晶晶,闫志凌,徐开林,等.套细胞淋巴瘤中SOX11差异性表达的研究进展[J].白血病:淋巴瘤,2018,27(5):308-311.
[8]He JX,Xi YF,Su LP,et al.Association of SOX11 gene expression with clinical features and prognosis of mantle cell lymphoma[J].Eur Rev Med Pharmacol Sci,2018,22(9):2556-2563.
[9]Beekman R,Amador V,Campo E.SOX11,a key oncogenic factor in mantle cell lymphoma[J].Curr Opin Hematol,2018,25(4):299-306.