角膜塑形镜控制青少年近视发展的短期疗效观察
摘要
目的:探讨角膜塑形镜控制青少年近视发展的短期疗效。方法:青少年近视患者88例,随机分为对照组和观察组各44例。对照组采用单光眼镜治疗,观察组采用角膜塑形镜治疗。比较两组患者戴镜前及戴镜1年后裸眼视力、屈光度数、角膜曲率、眼轴长度、角膜内皮细胞密度和中央角膜厚度,并采用裂隙灯显微镜检查患者戴镜治疗期间角结膜并发症的发生情况。结果:治疗后两组患者裸眼视力、屈光度数、角膜曲率均较治疗前下降,但观察组下降幅度小于对照组,差异均有统计学意义(P<0.05),治疗后两组患者眼轴长度均增加,但观察组增加幅度小于对照组,差异有统计学意义(P<0.05)。两组角膜内皮细胞密度治疗前后差异均无统计学意义(P>0.05),治疗后两组中央角膜厚度均下降,但观察组下降幅度小于对照组,差异有统计学意义(P<0.05)。对照组出现3例(6.81%)并发症,而观察组出现5例(11.36%)并发症,两组比较差异无统计学意义(P>0.05)。结论:角膜塑形镜较单光眼镜可明显延缓青少年近视患儿裸眼视力、屈光度数及角膜曲率、中央角膜厚度的下降趋势,减慢眼轴长度增加,并发症发生率及内皮细胞密度变化与佩戴单光眼镜相当。
引文
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[2]Xiong SY, Sankaridurg P, Naduvilath T, et al. Time spent in outdoor activities in relation to myopia prevention and control:a meta-analysis and systematic review[J]. Acta Ophthalmol(Copenh),2017, 95(6):551-566.
[3]Zhang DD, Zeng GQ, Hu JL, et al. Association of IGF1 polymorphism rs6214 with high myopia:A systematic review and meta-analysis[J]. Ophthalmic Genet, 2017, 38(5):434-439.
[4]Wylegala A. The effects of physical exercises on ocular physiology:a review[J]. J Glaucoma, 2016, 25(10):E843-E849.
[5]石一宁.中国儿童青少年近视防控流程的规范化建议--近视防控共识[C]//第十四届西北五省眼科学术大会论文集, 2013:93-94.
[6]Shi Y, Dong Y, Huang W, et al. Fecal microbiota transplantation for ulcerative colitis:a systematic review and Meta-Analysis:[J].PLoS One, 2016, 11(6):e0157259.
[7]Li X, Friedman IB, Medow NB, et al. Update on orthokeratology in managing progressive myopia in children:efficacy, mechanisms, and concerns[J]. JPediatrOphthalmol Strabismus, 2017,54(3):142-148.
[8]Pineles SL, Kraker RT, Vanderveen DK, et al. Atropine for the prevention of myopia progression in children a report by the American academy of ophthalmology[J]. Ophthalmology, 2017,124(12):1857-1866.