山东某三甲医院临床抗菌药物使用情况分析
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摘要
目的实地调研山东省某三甲医院临床抗菌药物使用现状,指导临床合理使用抗菌药物。方法采用实地回顾性调查的方法,随机抽取山东某三甲医院2018年上半年出院患者病历5 779份,随机抽取2018年任意1日的门诊处方200份,分析该院的抗菌药物使用强度及合理用药情况。结果该院某1工作日的抗菌药物处方占比为18.5%;门诊应用抗菌药物主要为口服用药;门诊无限制级抗菌药物使用;未发现联合应用抗菌药物的情况。该院2018年上半年的抗菌药物使用率为46.46%,使用频率略高。主要给药途径为静脉输液(72.66%),联合用药的比例较高。2018年上半年抗菌药物使用强度(AUD)前5类药物依次为氨基糖苷类、大环内酯类、硝基咪唑类、喹诺酮类和青霉素类。结论该院2018年上半年门诊抗菌药物处方的使用情况基本合理,但病房抗菌药物用药频率过高。
Objective To investigate the current situation of clinical antimicrobial use in a third-class hospital in Shandong Province,and to guide the rational use of antimicrobial drugs.Methods A retrospective field survey was conducted to randomly select 5779 medical records of discharged patients from a third-class hospital in Shandong Province in the first half of 2018 and 200 prescriptions on any day in 2018.Results The proportion of antimicrobial prescriptions on a certain working day was 18.5%; the main antimicrobial drugs used in outpatient department were oral; the use of unlimited antimicrobial drugs in outpatient department; and no combined use of antimicrobial drugs was found.The use rate of antibiotics in the first half of 2018 was 46.46%,and the frequency of use was slightly higher.The main route of administration was intravenous infusion(72.66%),and the proportion of combined medication was higher.The top 5 AUD drugs in the first half of 2018 were amino glycosides,microclines,nitroimidazoles,quinolones and penicillin.Conclusion The use of antimicrobial prescriptions in the first half of 2018 in our hospital is basically reasonable,but the frequency of antimicrobial use in the ward is too high.
Objective To investigate the current situation of clinical antimicrobial use in a third-class hospital in Shandong Province,and to guide the rational use of antimicrobial drugs.Methods A retrospective field survey was conducted to randomly select 5779 medical records of discharged patients from a third-class hospital in Shandong Province in the first half of 2018 and 200 prescriptions on any day in 2018.Results The proportion of antimicrobial prescriptions on a certain working day was 18.5%; the main antimicrobial drugs used in outpatient department were oral; the use of unlimited antimicrobial drugs in outpatient department; and no combined use of antimicrobial drugs was found.The use rate of antibiotics in the first half of 2018 was 46.46%,and the frequency of use was slightly higher.The main route of administration was intravenous infusion(72.66%),and the proportion of combined medication was higher.The top 5 AUD drugs in the first half of 2018 were amino glycosides,microclines,nitroimidazoles,quinolones and penicillin.Conclusion The use of antimicrobial prescriptions in the first half of 2018 in our hospital is basically reasonable,but the frequency of antimicrobial use in the ward is too high.
引文
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[2]张银华,刘敬伟,袁群,等.抗菌药物临床应用专项整治活动对医院住院患者抗菌药物使用的影响研究[J].中国医院药学杂志2016,36(22):2012-2015.
[3]吴积升,阮璐雅,苏银法,等.某院抗菌药物临床应用管理策略的利弊分析[J].中国乡村医药,2016,23(11):51-52.
[4]吴飞娜,费杏珍.某医院急诊内科应用抗菌药物的调查分析[J].中国医院统计,2016,23(2):109-110.
[5]盛垚,冯华,李景云.中山市某三甲医院2013-2015年抗菌药物不良反应发生状况调查分析[J].广州医药,2017,48(2):82-86.
[6]庞浩龙,孙利华.北京某医院心脏介入治疗抗菌药物使用情况分析[J].中国药事,2017,31(4):458-462.
[7]卢克鹏,谢小云,宋洪涛.某三级甲等医院骨科抗菌药物使用强度的制定[J].中国医院药学杂志,2016,36(6):492-498.
[8]梁晓丽,谭玲,谭琳,等.2012—2015年北京医院抗菌药物应用分析[J].临床药物治疗杂志,2016,14(4):54-59.
[9]李艳桃.某医院门诊处方抗菌药物不合理用药分析[J].临床医学研究与实践,2016,1(21):90-91.
[10]胡淑芬,梁景强,梁志芬.医院抗菌药物的应用调查与合理用药的措施分析[J].齐齐哈尔医学院学报,2016,37(21):2697-2698.
[11]胡玲峰,胡攀峰,韩国强.山西某县医院2012—2015年抗菌药物使用情况分析[J].山西医药杂志,2016,45(23):2745-2747.
[12]丁楠,朱青芳,马运芳,等.新疆某三甲医院2014—2016年住院患者特殊使用级抗菌药物应用分析[J].中国医药导报,2017,14(32):124-127,132.