重症肌无力神经电生理研究进展
摘要
重症肌无力(myasthenia gravis, MG)是最常见的神经肌肉接头疾病,主要表现为波动性的骨骼肌无力,临床表现形式多样。神经电生理在重症肌无力诊断中发挥重要作用。本文就神经电生理在重症肌无力的应用及研究进展进行阐述。
引文
[1] 汤晓芙.神经系统临床电生理学(下)[M].北京.人民军医出版社,2002:317-320.
[2] 中国免疫学会神经免疫学分会.中华医学会神经病学分会神经免疫学组.重症肌无力诊断和治疗中国专家共识[J].中国神经免疫学和神经病学杂志,2012,19(6):401-402.
[3] Sirin NG,Kocasoy Orhan E,Durmus H,et al.Repetitive nerve stimulation and jitter measurmentwith diaposable concentric needle electrode in newly diagnosed myasthenia gravis patients[J].Neurophysiol Clin,2018,48(5):261-267.
[4] 秦得营.重症肌无力的针电极肌电图研究[J].临床医药文献电子杂志,2016,3(3):583-586.
[5] 乔凯,黄俊,朱雯华,等.眼轮匝肌睑部重复电刺激在眼肌型重症肌无力诊断中的价值研究[J].中国临床神经科学,2015,23(1):29-32.
[6] Nikolic AV,Bojic SD,Rakocevic Stojanovic VM,et al.Electrophysiological findings in patients with low density lipoprotein receptor related protein 4 positive myasthenia gravis[J].Eur J Neurol,2016,23(11):1635-1641.
[7] Oh SJ,Hatanaka Y,Hemmi S,et al.Repetitive nerve stimulation of facial muscles in MuSK antibody-positive myasthenia gravis[J].Muscle Nerve,2006,33(4):500-504.
[8] 彭仕军.神经电生理对不同临床分型的重症肌无力诊断价值研究[J].中西医结合心脑血管病杂志,2018,16(9):1280-1282.
[9] Jing F,Cui F,Chen Z,et al.Clinical and Electrophysiological Markers in Myasthenia Gravis Patients[J].Eur Neurol,2015,74(1-2):22-27.
[10] Plomp JJ,Morsch M,Phillips WD,et al.Electrophysilolgical analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models[J].Exp Neurol,2015,270:41-54.
[11] 杨永,张雪玲,徐运.重症肌无力患者电生理检查的特点[J].中风与神经疾病杂志,2014,31(10):917-919.
[12] Oh SJ,Nagai T,Kizilay F,et al.One-minute exercise is best for evaluation of postexercise exhaustion in Myasthenia Gravis[J].Muscle Nerve,2014,50:413-416.
[13] Abraham A,Alabdali M,Alsulaiman A,et al.Repetitive facial nerve stimulation in myasthenia gravis 1min after muscle activation is inferior to testing a second muscle at rest[J].Clin Neurophysiol,2016,127(10):3294-3297.
[14] Shi L,Liu HF,Zhang M,et al.Determination of the normative values of the masseter muscle by single-fiber electromyography in myasthenia gravis patients[J].Int J Clin Exp Med,2015,8(10):19424-19429.
[15] 梁银杏,陈子怡,葛辉,等.神经电生理检查判断眼肌型重症肌无力的敏感度分析[J].中国临床神经科学,2010,18(4):407-409.
[16] Morren JA,Levin KH,Shields RW.Diagnostic accuracy of single fiber electromyography for myasthenia gravis in patients followed longitudinally[J].J Clin Neurophysiol,2016,33(5):469-474.
[17] Padua L,Caliandro P,Dilasi G,et al.Reliability of SFEMG in diagnosing myasthenia gravis:sensitivity and specificity calculated on 100 prospective cases[J].Clin Neurophysiol,2014,125(6):1270-1273.
[18] Lo YL,Najjar RP,Teo KY,et al.A reappraisal of diagnostic tests for myasthenia gravis in a large Asian cohort[J].J Neurol Sci,2017,376:153-158.
[19] Guan YZ,Cui LY,Liu MS,et al.Single-fiber electromyography in the extensor digitorum communis for the predictive prognosis of ocular myasthenia gravis:a retrospective study of 102 cases[J].Chin Med J(Engl),2015,128(20):2783-2786.
[20] Jacob S,Vieqas S,Leite MI,et al.Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis[J].Arch Neurol,2012,69(8):994-1001.
[21] Rakocevic G,Moster M,Floeter MK.Single-fiber electromyography in the orbicularis oculi muscle in patients with ocular myasthenia gravis symptoms:does abnormal jitter predict response to treatment?[J].BMC Neurol,2017,17(1):108.
[22] Sanders DB,Massey JM.Does change in neuromuscular jitter predict or corrlelate with clinical change in MG?[J].Muscle Nerve,2017,56(1):45-50.
[23] Baruca M,Leonardis L,Podnar S,et al.Single fiber EMG as a prognostic tool in myasthenia gravis[J].Muscle Nerve,2016,54(6):1034-1040.
[24] Gosavi TD,Huang GZ,Fook-Chong S,et al.Predictive Value of Electrophysiology for Presence of Thymic Pathology in Myasthenia Gravis[J].J Neuromusclul Dis,2014,1(2):163-168.
[25] Kannaditharayil D,Napier F,Granit V,et al.Abnormal spontaneous activity on needle electromyography in myasthenia gravis[J].Muscle Nerve,2017,56(2):E11-E12.
[26] 赖重媛,冯扬,梁银杏,等.伴自发电位重症肌无力的临床及电生理特点[J].中国神经精神疾病杂志,2016,42(9):527-531.
[27] Plomp JJ,Morsch M,Phillips WD,et al.Electrophysilolgical analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models[J].Exp Neurol,2015,270:41-54.
[28] 石磊.咬肌单纤维肌电图在重症肌无力和炎性肌病中的应用研究[D].郑州大学.2015.
[29] Suzuki S.Autoantibodies in thymoma-associated myasthenia gravis and their clinical significance[J].Brain Nerve,2011,63(7):705-712.
[30] Sirin NG,Kocasoy OE,Durmus H,et al.Repetitive nerve stimulation and jitter measurment with diaposable concentric needle electrode in newly diagnosed myasthenia gravis patients[J].Neurophysiol Clin,2018,48(5):261-267.
[31] Sarrigiannis PG,Kennett RP,Read S,et al.Single-fiber EMG with a concentric needle electrode:validation in myasthenia gravis[J].Muscle Nerve,2006,33(1):61-65.
[32] Sciacca G,Reqqio E,Mostile G,et al.C linical and CN-SFEMG evaluation of neostigmine test in myasthenia gravis[J].Neurol Sci,2018,39(2):341-345.
[33] Wang J,Ji F,Luo B.Jitter analysis with concentric needle electrodes in the extensor digitorum communis for the diagnosis of myasthenia gravis:a pilot study[J].Chin Med J(Engl),2014,127(18):3209-3212.
[34] Papathanasiou ES,Zamba-Papanicolaou E.Single fiber electromyography:what type of needle should I use?[J].Clin Neurophysiol,2013,124(11):2077-2078.
[35] 翦凡,王化冰,陈娜,等.远端型重症肌无力的临床和电生理观察[J].中华医学杂志,2017,97(37):2894-2897.
[36] Němcová A,Janou?ek O,Vítek M,et al.Testing of features for fatigue detection in EOG[J].Biomed Mater Eng,2017,28(4):379-392.
[37] Liang T,Boulos MI,Murray BJ,et al.Detection of myasthenia gravis using electrooculography signals[J].Conf Proc IEEE Eng Med Biol Soc,2016,2016:896-899.
[38] Nikolic A,Basta I,Stojanovic VR,et al.Myopathy changes detected by quantitative electromyography in patients with MuSK and AChR positive myasthenia gravis[J].J Clin Neurosci,2016,27:126-129.
[2] 中国免疫学会神经免疫学分会.中华医学会神经病学分会神经免疫学组.重症肌无力诊断和治疗中国专家共识[J].中国神经免疫学和神经病学杂志,2012,19(6):401-402.
[3] Sirin NG,Kocasoy Orhan E,Durmus H,et al.Repetitive nerve stimulation and jitter measurmentwith diaposable concentric needle electrode in newly diagnosed myasthenia gravis patients[J].Neurophysiol Clin,2018,48(5):261-267.
[4] 秦得营.重症肌无力的针电极肌电图研究[J].临床医药文献电子杂志,2016,3(3):583-586.
[5] 乔凯,黄俊,朱雯华,等.眼轮匝肌睑部重复电刺激在眼肌型重症肌无力诊断中的价值研究[J].中国临床神经科学,2015,23(1):29-32.
[6] Nikolic AV,Bojic SD,Rakocevic Stojanovic VM,et al.Electrophysiological findings in patients with low density lipoprotein receptor related protein 4 positive myasthenia gravis[J].Eur J Neurol,2016,23(11):1635-1641.
[7] Oh SJ,Hatanaka Y,Hemmi S,et al.Repetitive nerve stimulation of facial muscles in MuSK antibody-positive myasthenia gravis[J].Muscle Nerve,2006,33(4):500-504.
[8] 彭仕军.神经电生理对不同临床分型的重症肌无力诊断价值研究[J].中西医结合心脑血管病杂志,2018,16(9):1280-1282.
[9] Jing F,Cui F,Chen Z,et al.Clinical and Electrophysiological Markers in Myasthenia Gravis Patients[J].Eur Neurol,2015,74(1-2):22-27.
[10] Plomp JJ,Morsch M,Phillips WD,et al.Electrophysilolgical analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models[J].Exp Neurol,2015,270:41-54.
[11] 杨永,张雪玲,徐运.重症肌无力患者电生理检查的特点[J].中风与神经疾病杂志,2014,31(10):917-919.
[12] Oh SJ,Nagai T,Kizilay F,et al.One-minute exercise is best for evaluation of postexercise exhaustion in Myasthenia Gravis[J].Muscle Nerve,2014,50:413-416.
[13] Abraham A,Alabdali M,Alsulaiman A,et al.Repetitive facial nerve stimulation in myasthenia gravis 1min after muscle activation is inferior to testing a second muscle at rest[J].Clin Neurophysiol,2016,127(10):3294-3297.
[14] Shi L,Liu HF,Zhang M,et al.Determination of the normative values of the masseter muscle by single-fiber electromyography in myasthenia gravis patients[J].Int J Clin Exp Med,2015,8(10):19424-19429.
[15] 梁银杏,陈子怡,葛辉,等.神经电生理检查判断眼肌型重症肌无力的敏感度分析[J].中国临床神经科学,2010,18(4):407-409.
[16] Morren JA,Levin KH,Shields RW.Diagnostic accuracy of single fiber electromyography for myasthenia gravis in patients followed longitudinally[J].J Clin Neurophysiol,2016,33(5):469-474.
[17] Padua L,Caliandro P,Dilasi G,et al.Reliability of SFEMG in diagnosing myasthenia gravis:sensitivity and specificity calculated on 100 prospective cases[J].Clin Neurophysiol,2014,125(6):1270-1273.
[18] Lo YL,Najjar RP,Teo KY,et al.A reappraisal of diagnostic tests for myasthenia gravis in a large Asian cohort[J].J Neurol Sci,2017,376:153-158.
[19] Guan YZ,Cui LY,Liu MS,et al.Single-fiber electromyography in the extensor digitorum communis for the predictive prognosis of ocular myasthenia gravis:a retrospective study of 102 cases[J].Chin Med J(Engl),2015,128(20):2783-2786.
[20] Jacob S,Vieqas S,Leite MI,et al.Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis[J].Arch Neurol,2012,69(8):994-1001.
[21] Rakocevic G,Moster M,Floeter MK.Single-fiber electromyography in the orbicularis oculi muscle in patients with ocular myasthenia gravis symptoms:does abnormal jitter predict response to treatment?[J].BMC Neurol,2017,17(1):108.
[22] Sanders DB,Massey JM.Does change in neuromuscular jitter predict or corrlelate with clinical change in MG?[J].Muscle Nerve,2017,56(1):45-50.
[23] Baruca M,Leonardis L,Podnar S,et al.Single fiber EMG as a prognostic tool in myasthenia gravis[J].Muscle Nerve,2016,54(6):1034-1040.
[24] Gosavi TD,Huang GZ,Fook-Chong S,et al.Predictive Value of Electrophysiology for Presence of Thymic Pathology in Myasthenia Gravis[J].J Neuromusclul Dis,2014,1(2):163-168.
[25] Kannaditharayil D,Napier F,Granit V,et al.Abnormal spontaneous activity on needle electromyography in myasthenia gravis[J].Muscle Nerve,2017,56(2):E11-E12.
[26] 赖重媛,冯扬,梁银杏,等.伴自发电位重症肌无力的临床及电生理特点[J].中国神经精神疾病杂志,2016,42(9):527-531.
[27] Plomp JJ,Morsch M,Phillips WD,et al.Electrophysilolgical analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models[J].Exp Neurol,2015,270:41-54.
[28] 石磊.咬肌单纤维肌电图在重症肌无力和炎性肌病中的应用研究[D].郑州大学.2015.
[29] Suzuki S.Autoantibodies in thymoma-associated myasthenia gravis and their clinical significance[J].Brain Nerve,2011,63(7):705-712.
[30] Sirin NG,Kocasoy OE,Durmus H,et al.Repetitive nerve stimulation and jitter measurment with diaposable concentric needle electrode in newly diagnosed myasthenia gravis patients[J].Neurophysiol Clin,2018,48(5):261-267.
[31] Sarrigiannis PG,Kennett RP,Read S,et al.Single-fiber EMG with a concentric needle electrode:validation in myasthenia gravis[J].Muscle Nerve,2006,33(1):61-65.
[32] Sciacca G,Reqqio E,Mostile G,et al.C linical and CN-SFEMG evaluation of neostigmine test in myasthenia gravis[J].Neurol Sci,2018,39(2):341-345.
[33] Wang J,Ji F,Luo B.Jitter analysis with concentric needle electrodes in the extensor digitorum communis for the diagnosis of myasthenia gravis:a pilot study[J].Chin Med J(Engl),2014,127(18):3209-3212.
[34] Papathanasiou ES,Zamba-Papanicolaou E.Single fiber electromyography:what type of needle should I use?[J].Clin Neurophysiol,2013,124(11):2077-2078.
[35] 翦凡,王化冰,陈娜,等.远端型重症肌无力的临床和电生理观察[J].中华医学杂志,2017,97(37):2894-2897.
[36] Němcová A,Janou?ek O,Vítek M,et al.Testing of features for fatigue detection in EOG[J].Biomed Mater Eng,2017,28(4):379-392.
[37] Liang T,Boulos MI,Murray BJ,et al.Detection of myasthenia gravis using electrooculography signals[J].Conf Proc IEEE Eng Med Biol Soc,2016,2016:896-899.
[38] Nikolic A,Basta I,Stojanovic VR,et al.Myopathy changes detected by quantitative electromyography in patients with MuSK and AChR positive myasthenia gravis[J].J Clin Neurosci,2016,27:126-129.