摘要
以芳香醛和丙二睛为原料,NaCl为助磨剂,在无催化剂、无溶剂的条件下,通过球磨反应,以较高的收率合成了一系列Knoevenagel缩合反应产物,产物结构经过1H NMR和MS表征。本方法具有条件温和,后处理简单,环境友好,产率高等优点。
A series of Knoevenagel condensation productions were synthesized from aromatic aldehydes and malononitrile by ball milling in the grinding aid of NaCl without catalyst and solvent. The structures of the productions were confirmed by1 H NMR and MS. The method has mild reaction condition, simple post processing, environmental friendliness and higher yields.
引文
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