MR扩散加权成像与CT增强扫描在肝硬化分级诊断中的应用价值
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摘要
目的探讨比较MR扩散加权成像与CT增强扫描在肝硬化分级诊断中的应用价值。方法选取光山县中医院2014年6月~2015年12月收治的肝硬化患者50例,所有患者均给予CT增强扫描、MR扩散加权成像,观察不同b值的表现扩散系数(apparent diffusion coefficient,ADC)和CT扫描结果,并与健康志愿者肝脏ADC值进行测量比较。结果当b=200s/mm~2、400s/mm~2、600s/mm~2时,不同肝硬化Child分级ADC值比较差异有统计学意义(P<0.05);当b=800s/mm~2时患者与健康志愿者肝脏ADC值比较无显著差异(P>0.05)。结论在肝硬化分级诊断中MR扩散加权成像诊断价值更好,而CT增强扫描小肝癌的检出率更高,需根据不同的临床需要选择合适的诊断方法。
Objective To investigate the application value of MR diffusion-weighted imaging and CT enhanced scanning in the grading diagnosis of liver cirrhosis. Methods Fifty patients with cirrhosis treated in traditional Chinese medicine hospital in Guangshan county from June 2014 to December 2015 were enrolled into this study. All patients were performed CT enhanced scanning and MR diffusion-weighted imaging to observe the apparent diffusion coefficient(ADC) of different b values as well as the CT scanning results, which were compared with those of healthy volunteers. Results The ADC values of liver cirrhosis patients with different Child grades were significantly different when b=200 s/mm~2, 400 s/mm~2, 600 s/mm~2(P < 0.05); There was no significant difference in ADC values between patients and healthy volunteer when b=800 s/mm~2(P > 0.05). Conclusion MR diffusion-weighted imaging is more valuable in the grading diagnosis of liver cirrhosis, while CT enhanced scanning possesses higher detection rate of small hepatocellular carcinoma. The appropriate diagnostic methods should be employed to satisfy specific clinical demands.
Objective To investigate the application value of MR diffusion-weighted imaging and CT enhanced scanning in the grading diagnosis of liver cirrhosis. Methods Fifty patients with cirrhosis treated in traditional Chinese medicine hospital in Guangshan county from June 2014 to December 2015 were enrolled into this study. All patients were performed CT enhanced scanning and MR diffusion-weighted imaging to observe the apparent diffusion coefficient(ADC) of different b values as well as the CT scanning results, which were compared with those of healthy volunteers. Results The ADC values of liver cirrhosis patients with different Child grades were significantly different when b=200 s/mm~2, 400 s/mm~2, 600 s/mm~2(P < 0.05); There was no significant difference in ADC values between patients and healthy volunteer when b=800 s/mm~2(P > 0.05). Conclusion MR diffusion-weighted imaging is more valuable in the grading diagnosis of liver cirrhosis, while CT enhanced scanning possesses higher detection rate of small hepatocellular carcinoma. The appropriate diagnostic methods should be employed to satisfy specific clinical demands.
引文
[1]梁长松,陈忠,李伟峰等.磁共振扩散加权成像在卵巢囊腺癌与囊腺瘤鉴别诊断中的价值[J].中国CT和MRI杂志,2015,(3):83-86.
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[3]齐晓辉,时高峰,王琦,等.MR弥散加权成像及ADC值对小肝癌的诊断价值[J].实用放射学杂志,2013,29(7):1112-1115.
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[5]丁伟伟,郭玉林,牛建栋,等.MR和CT动态增强扫描对肝硬化背景下小肝癌的比较研究[J].临床放射学杂志,2011,30(7):984-987.
[2]杜飞,郭艳霞.MRI与CT在老年多发性脑梗死病人诊断中的临床结果比较[J].中国老年学杂志,2012,32(3):487-489.
[3]齐晓辉,时高峰,王琦,等.MR弥散加权成像及ADC值对小肝癌的诊断价值[J].实用放射学杂志,2013,29(7):1112-1115.
[4]侯文静,朱晓琳.肝癌射频治疗后影像学特征研究进展[J].中国肿瘤临床,2012,39(14):1000-1002.
[5]丁伟伟,郭玉林,牛建栋,等.MR和CT动态增强扫描对肝硬化背景下小肝癌的比较研究[J].临床放射学杂志,2011,30(7):984-987.