抗癫痫药物对急性脑梗死患者预后影响的研究进展
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摘要
脑梗死是指由脑血栓形成或脑栓死引起的脑组织缺血坏死。目前国内外已有较多治疗药物对脑梗死患者预后影响的临床研究,但大多集中在抗凝药物回顾性研究,相应的研究对于抗癫痫药物对急性脑梗死患者预后影响对患者疗效判断等方面同样具有十分重要的意义,并可能为临床治疗提供新的思路。该文主要对抗癫痫药物对急性脑梗死患者预后影响的相应研究进行综述。
Cerebral infarction refers to the ischemic necrosis of brain tissues caused by the cerebral thrombosis or cerebral embolism, currently, there are most clinical researches on the effect of treatment drugs for the prognosis of patients with cerebral infarction but most researches focus on the anticoagulants, which is of important significance to the curative effect determination of anti-epileptic drugs on the prognosis of patients with acute cerebral infarction and provides a new thought for the clinical treatment, and the paper mainly elaborates the effect of anti-epileptic drugs on the prognosis of patients with acute cerebral infarction.
Cerebral infarction refers to the ischemic necrosis of brain tissues caused by the cerebral thrombosis or cerebral embolism, currently, there are most clinical researches on the effect of treatment drugs for the prognosis of patients with cerebral infarction but most researches focus on the anticoagulants, which is of important significance to the curative effect determination of anti-epileptic drugs on the prognosis of patients with acute cerebral infarction and provides a new thought for the clinical treatment, and the paper mainly elaborates the effect of anti-epileptic drugs on the prognosis of patients with acute cerebral infarction.
引文
[1]Ye X,Chopp M,Liu x,et al.Niaspan reduces high-mobility group box 1/receptor for advanced glycation end products after stroke in type-1 diabetic rats[J].Neurostienee,2011,190:339-345.
[2]Heiss WD.The ischemic penumbra:how does tissue injury evolve[J].Ann N Y Acad Sci,2012,1268:26-34.
[3]Bombardieri R,Moavero R,Roberto D,et al.Pancreatic neuroendocrine tumor in a child with a tuberous sclerosis complex 2(TSC2)mutation[J].Endocr Pract,2013,19(5):124-128.
[4]Park JB,Kang DY,Yang HM,et al.Serum alkaline phosphatase is a predictor of mortality,myocardial infarction,or stent thrombosis after implantation of coronary drugeluting stent[J].Eur Heart J,2013,34(12):920-931.
[5]M Peltola,TT Seppl,A Malmivaara,et al.Individual and Regional-level Factors Contributing to Variation in Length of Stay After Cerebral Infarction in Six European Countries[J].Health Economics,2015,2:38-52.
[6]ZP Li,LB Liang,C Chen,et al.Association Between Serum Uric Acid and Acute Cerebral Infarction:a Case Control Study[J].Sichuan da xue xue bao,2015,46(5):744-746.
[7]BJ Kim,YH Kim,N Kim,et al.Lesion Location-Based Prediction of Visual Field Improvement after Cerebral Infarction[J].Plos One,2015,10(11):143882.
[8]R Ojha,D Huang,H An,et al.Distribution of ischemic infarction and stenosis of intra-and extracranial arteries in young Chinese patients with ischemic stroke[J].BMC Cardiovascular Disorders,2015,15(1):1-9.
[9]K Tada,K Uchida,H Kanayama,et al.Usefulness of Iterative Reconstruction Method in the Field of Acute Cerebral Infarction Computed Tomography Examination[J].Nihon Hoshasen Gijutsu Gakkai Zasshi,2015,71(11):1090-1095.
[10]HR Lu,SW Song,KY Han,et al.Adenosine Al Receptor Mediated Neuroprotection of Shenmai Injection on Rat Cerebral Ischemia/Reperfusion Injury:an Experimental Study[J].Zhongguo Zhong xi yi jie he za zhi,2015,35(9):1109.
[11]Y Li,S Suo,L Mao.Acute myocardial/cerebral infarction as first/relapse manifestation in one acute promyelocytic leukemia patient[J].International Journal of Clinical&Experiment Medicine,2015,8(8):14210-14213.
[12]MA Hawkes,JE Arena,C Rollán,et al.Bilateral Paramedian Thalamic Infarction[J].Neurologist,2015,20(5):89-92.
[13]HB Lee,J Kim,SH Kim,et al.Association between Serum Alkaline Phosphatase Level and Cerebral Small Vessel Disease[J].Plos One,2015,10(11):143355.
[14]SV Demyanenko,SN Panchenko,AB Uzdensky.Expression of Neuronal and Signaling Proteins in Penumbra around a Photothrombotic Infarction Core in Rat Cerebral Cortex[J].Biochemistry Biokhimiia,2015,80(6):790-799.
[15]MB Akpinar,V Sahin,N Sahin,et al.Previous chroniccerebral infarction is predictive for newcerebralischemia after carotid endarterectomy[J].Journal of Cardiothoracic Surgery,2015,10(1):1-8.
[16]YC Meng,ZY Ding,HQ Wang,et al.Effect of micro RNA-155 on angiogenesis aftercerebralinfarction of rats through AT1R/VEGFR2 pathway[J].Asian Pacific Journal of Tropical Medicine,2015,8(10):810-816.
[17]L Lorente,MM Martín,P Abreugonzález,et al.Serum malondialdehyde levels in patients with malignant middle cerebral artery infarction are associated with mortality[J].Plos One,2014,10(5):125893.
[18]Sasiwarang Goya Wannamethee,Naveed Sattar,Olia Papcosta,et al.Alkaline phosphatase,serum phosphate,and incident cardiovascular disease and total mortality in older men[J].Arterioscler Thromb Vasc Biol,2013,33(5):1070-1076.
[19]B Edvardsson.Hypertensive encephalopathy and?cerebralinfarction[J].Springer Plus,2014,3(1):1-9.
[20]M Sabrie,N Berhoune,N Nighoghossian.Alien hand syndrome and paroxystic dystonia after right posterior?cerebral artery territoryinfarction[J].Neurological Sciences,2015,36(9):1-2.
[21]K Li,J Jia,Z Wang,et al.Elevated Serum Levels of NSE and S-100βCorrelate with Increased Risk of Acute Cerebral Infarction in Asian Populations[J].Medical Science Monitor International Medical Journal of Experimental&Clinical Research,2014,21:1879-1888.
[22]GL Meng,Y Tan,M Fang,et al.Paradoxical Elevation of High Density Lipoprotein Cholesterol in Association with Lacunar-Type Cerebral Infarction[J].Medical Science Monitor International Medical Journal of Experimental&Clinical Research,2014,21:1872-1878.
[23]R Prasad,S Suri,Shambhavi,et al.Ischemic infarction of cerebral cortex in a child with scorpion sting envenomation[J].The Indian Journal of Pediatrics,2014,81(7):705-706.
[24]Kulstad EB,Courtney DM,Waller D.Induction of therapeutic hypothermia via the esophagus:a proof of concept study[J].World journal of emergency medicine,2012(2):118-122.
[25]Dou L,Gao H,Lu L,et al.Bispectral index in predicting the prognosis of patients with coma in intensive care unit[J].World journal of emergency medicine,2014(1):53-56.
[2]Heiss WD.The ischemic penumbra:how does tissue injury evolve[J].Ann N Y Acad Sci,2012,1268:26-34.
[3]Bombardieri R,Moavero R,Roberto D,et al.Pancreatic neuroendocrine tumor in a child with a tuberous sclerosis complex 2(TSC2)mutation[J].Endocr Pract,2013,19(5):124-128.
[4]Park JB,Kang DY,Yang HM,et al.Serum alkaline phosphatase is a predictor of mortality,myocardial infarction,or stent thrombosis after implantation of coronary drugeluting stent[J].Eur Heart J,2013,34(12):920-931.
[5]M Peltola,TT Seppl,A Malmivaara,et al.Individual and Regional-level Factors Contributing to Variation in Length of Stay After Cerebral Infarction in Six European Countries[J].Health Economics,2015,2:38-52.
[6]ZP Li,LB Liang,C Chen,et al.Association Between Serum Uric Acid and Acute Cerebral Infarction:a Case Control Study[J].Sichuan da xue xue bao,2015,46(5):744-746.
[7]BJ Kim,YH Kim,N Kim,et al.Lesion Location-Based Prediction of Visual Field Improvement after Cerebral Infarction[J].Plos One,2015,10(11):143882.
[8]R Ojha,D Huang,H An,et al.Distribution of ischemic infarction and stenosis of intra-and extracranial arteries in young Chinese patients with ischemic stroke[J].BMC Cardiovascular Disorders,2015,15(1):1-9.
[9]K Tada,K Uchida,H Kanayama,et al.Usefulness of Iterative Reconstruction Method in the Field of Acute Cerebral Infarction Computed Tomography Examination[J].Nihon Hoshasen Gijutsu Gakkai Zasshi,2015,71(11):1090-1095.
[10]HR Lu,SW Song,KY Han,et al.Adenosine Al Receptor Mediated Neuroprotection of Shenmai Injection on Rat Cerebral Ischemia/Reperfusion Injury:an Experimental Study[J].Zhongguo Zhong xi yi jie he za zhi,2015,35(9):1109.
[11]Y Li,S Suo,L Mao.Acute myocardial/cerebral infarction as first/relapse manifestation in one acute promyelocytic leukemia patient[J].International Journal of Clinical&Experiment Medicine,2015,8(8):14210-14213.
[12]MA Hawkes,JE Arena,C Rollán,et al.Bilateral Paramedian Thalamic Infarction[J].Neurologist,2015,20(5):89-92.
[13]HB Lee,J Kim,SH Kim,et al.Association between Serum Alkaline Phosphatase Level and Cerebral Small Vessel Disease[J].Plos One,2015,10(11):143355.
[14]SV Demyanenko,SN Panchenko,AB Uzdensky.Expression of Neuronal and Signaling Proteins in Penumbra around a Photothrombotic Infarction Core in Rat Cerebral Cortex[J].Biochemistry Biokhimiia,2015,80(6):790-799.
[15]MB Akpinar,V Sahin,N Sahin,et al.Previous chroniccerebral infarction is predictive for newcerebralischemia after carotid endarterectomy[J].Journal of Cardiothoracic Surgery,2015,10(1):1-8.
[16]YC Meng,ZY Ding,HQ Wang,et al.Effect of micro RNA-155 on angiogenesis aftercerebralinfarction of rats through AT1R/VEGFR2 pathway[J].Asian Pacific Journal of Tropical Medicine,2015,8(10):810-816.
[17]L Lorente,MM Martín,P Abreugonzález,et al.Serum malondialdehyde levels in patients with malignant middle cerebral artery infarction are associated with mortality[J].Plos One,2014,10(5):125893.
[18]Sasiwarang Goya Wannamethee,Naveed Sattar,Olia Papcosta,et al.Alkaline phosphatase,serum phosphate,and incident cardiovascular disease and total mortality in older men[J].Arterioscler Thromb Vasc Biol,2013,33(5):1070-1076.
[19]B Edvardsson.Hypertensive encephalopathy and?cerebralinfarction[J].Springer Plus,2014,3(1):1-9.
[20]M Sabrie,N Berhoune,N Nighoghossian.Alien hand syndrome and paroxystic dystonia after right posterior?cerebral artery territoryinfarction[J].Neurological Sciences,2015,36(9):1-2.
[21]K Li,J Jia,Z Wang,et al.Elevated Serum Levels of NSE and S-100βCorrelate with Increased Risk of Acute Cerebral Infarction in Asian Populations[J].Medical Science Monitor International Medical Journal of Experimental&Clinical Research,2014,21:1879-1888.
[22]GL Meng,Y Tan,M Fang,et al.Paradoxical Elevation of High Density Lipoprotein Cholesterol in Association with Lacunar-Type Cerebral Infarction[J].Medical Science Monitor International Medical Journal of Experimental&Clinical Research,2014,21:1872-1878.
[23]R Prasad,S Suri,Shambhavi,et al.Ischemic infarction of cerebral cortex in a child with scorpion sting envenomation[J].The Indian Journal of Pediatrics,2014,81(7):705-706.
[24]Kulstad EB,Courtney DM,Waller D.Induction of therapeutic hypothermia via the esophagus:a proof of concept study[J].World journal of emergency medicine,2012(2):118-122.
[25]Dou L,Gao H,Lu L,et al.Bispectral index in predicting the prognosis of patients with coma in intensive care unit[J].World journal of emergency medicine,2014(1):53-56.