镍铬合金在义齿中的应用进展及风险分析
|
摘要
镍铬合金为常用的义齿加工材料,用于制作义齿,以修复患者牙体牙列的缺损和缺失。由于镍铬合金具备优秀的理化性能、良好的加工性能和低廉的价格而被广泛用于义齿的制作,但是合金中镍元素析出会导致镍过敏、细胞毒性、全身毒性等风险。本文总结了镍铬合金在义齿中的应用情况,分析了镍元素析出引发的风险和控制措施,供生产企业及使用人员参考,以提高此类产品的安全性。
It is well known that nickel-chromium alloy is a commonly used denture material. It is used to make denture to repair the defect and missing of the patient's teeth. Nickel-chromium alloy is widely used in the manufacture of denture due to its excellent physical and chemical properties, good processing performance and low price. However, the precipitation of nickel can lead to nickel allergy, cytotoxicity and systemic toxicity. The application of nickel-chromium alloy in denture was summarized and the risk and control measures of nickel precipitation were analyzed in this paper. It is hoped that this study can be used by manufacturers and users to improve the safety of such products.
It is well known that nickel-chromium alloy is a commonly used denture material. It is used to make denture to repair the defect and missing of the patient's teeth. Nickel-chromium alloy is widely used in the manufacture of denture due to its excellent physical and chemical properties, good processing performance and low price. However, the precipitation of nickel can lead to nickel allergy, cytotoxicity and systemic toxicity. The application of nickel-chromium alloy in denture was summarized and the risk and control measures of nickel precipitation were analyzed in this paper. It is hoped that this study can be used by manufacturers and users to improve the safety of such products.
引文
[1]Aundoea S.World Population Prospects[M].New York:United Nations Publications,2017.
[2]王春晓,张麒,阳扬,等.中国成年及老年人预防性口腔卫生行为状况[J].中国公共卫生,2015,31(2):129-132.
[3]程竑,曾晓莉,李存荣,等.上海市1579名中老年人牙缺失与义齿修复情况调查[J].上海口腔医学,2009,18(6):561-566.
[4]金芮竹,赵驰.镍铬合金材料与口腔软组织的生物相容性[J].中国组织工程研究,2012,16(21):3949-3958.
[5]Al Jabbari YS.Physico-mechanical properties and prosthodontic applications of Co-Cr dental alloys:a review of the literature[J].J Adv Prosthodont,2014,6(2):138-145.
[6]Sheibaninia A.Effect of Thermocycling on nickel release from orthodontic arch wires:an in vitro study[J].Biol Trace Elem Res,2014,162(1-3):353-359.
[7]Martíncameán A,Josá,Melladogarcía P,et al.In vitro and in vivo evidence of the cytotoxic and genotoxic effects of metal ions released by orthodontic appliances:A review[J].Environ Toxicol Pharmacol,2015,40(1):86-113.
[8]Mei-Feng HE,Wang H,Jiang H,et al.Effect of hydrogen peroxide concentration on surface properties of Ni-Cr alloys[J].T Nonferr Metal Soc,2016,26(5):1353-1358.
[9]Borg W,Cassar G,Camilleri L,et al.Surface microstructural changes and release of ions from dental metal alloy removable prostheses in patients suffering from acid reflux[J].JProsthodont,2016,27(2).
[10]Bolat G,Paduraru C,Strugaru SCI,et al.Stability of NICRdental alloy after 15 years of service[J].Rev Roum Chim,2014,59(2):91-96.
[11]Habibzadeh S,Rajati HR,Hajmiragha H,et al.Fracture resistances of zirconia,cast Ni-Cr,and fiber-glass composite posts under all-ceramic crowns in endodontically treated premolars[J].J Adv Prosthodont,2017,9(3):170-175.
[12]Paulino SM,Leal MB,Pagnano VO,et al.The castability of pure titanium compared with Ni-Cr and Ni-Cr-Be alloys[J].JProsthet Dent,2007,98(6):445-454.
[13]Yu W,Qian C,Weng W,et al.Effects of lipopolysaccharides on the corrosion behavior of Ni-Cr and Co-Cr alloys[J].J Prosthet Dent,2016,116(2):286-291.
[14]Silva LJD,Leal MB,Valente MLC,et al.Effect of casting atmosphere on the marginal deficiency and misfit of Ni-Cr alloys with and without beryllium[J].J Prosthet Dent,2017,118(1):83-88.
[15]Hong KH,Kim JH,Chang K,et al.The role of Cr on oxide formation in Ni-Cr alloys:A theoretical study[J].Comp Mater Sci,2018,142:185-191.
[16]Ameer MA,Fekry MA,Bahr MA.Effect of Streptococcus mutans on the corrosion behavior of Nano-Coating Ni-Cr Dental Alloy[J].Inter J Electr Sci,2017,12(10):9652-9664.
[17]Mahmood B,Hammert WC.Metal implant allergy[J].J Hand Surg-Am,2015,40(4):831-834.
[18]Palacios MAD,Lopez-Salgueiro R,Sanchez GM,et al.Chronic urticaria after implantation of a mitral annuloplasty ring in a nickel-allergic patient[J].J Invest Allerg Clin,2017,27(1):74-75.
[19]Guerra A,Kirkwood M.Severe generalized dermatitis in a nickel-allergic patient with a popliteal artery nitinol stent[J].JVasc Surg Cases In,2017,3(1):23-25.
[20]Ahlstrom MG,Thyssen JP,Menne T,et al.Prevalence of nickel allergy in Europe following the EU Nickel Directive-a review[J].Contact Dermatitis,2017,77(4):193-200.
[21]Goldenberg A,Vassantachart J,Lin EJ,et al.Nickel allergy in adults in the U.S.:1962 to 2015[J].Derm Cont Atopic Occup Drug,2015,26(5):216.
[22]Zambelli B,Uversky VN,Ciurli S.Nickel impact on human health:An intrinsic disorder perspective[J].BBA-Proteins Proteom,2016,1864(12):1714-1731.
[23]Deo KM,Pages BJ,Ang DL,et al.Transition metal intercalators as anticancer agents-recent advances[J].Int J Mol Sci,2016,17(11):1818.
[24]Issa Y,Brunton P,Waters CM,et al.Cytotoxicity of metal ions to human oligodendroglial cells and human gingival fibroblasts assessed by mitochondrial dehydrogenase activity[J].Dent Mater,2008,24(2):281-287.
[25]Yao Y,Costa M.Toxicogenomic effect of nickel and beyond[J].Arch Toxicol,2014,88(9):1645-1650.
[26]Milheiro A,Nozaki K,Kleverlaan CJ,et al.In vitro cytotoxicity of metallic ions released from dental alloys[J].Odontology,2016,104(2):136-142.
[27]Zambelli B,Ciurli S.Nickel and human health[J].Metal Ions Life Sci,2013,13:321-357.
[28]El-Shafei HM.Assessment of liver function among nickel-plating workers in Egypt[J].East Mediterr Health J,2011,17(6):490-494.
[29]Hackett RL,Sunderma FW.Studies of Nickel carcinogenesis-acute reactions of pulmonary alveolar wall to Nickel carbonyl[J].Am J Pathol,1967,50(6):46.
[30]Kasprzak KS,Sunderman FW,Salnikow K.Nickel carcinogenesis[J].Mutat Res-Rev Mutat,2003,533(1):67-97.
[31]Jones SB,Taylor RL,Colligon JS,et al.Effect of element concentration on nickel release from dental alloys using a novel ion beam method[J].Dent Mater,2010,26(3):249-256.
[2]王春晓,张麒,阳扬,等.中国成年及老年人预防性口腔卫生行为状况[J].中国公共卫生,2015,31(2):129-132.
[3]程竑,曾晓莉,李存荣,等.上海市1579名中老年人牙缺失与义齿修复情况调查[J].上海口腔医学,2009,18(6):561-566.
[4]金芮竹,赵驰.镍铬合金材料与口腔软组织的生物相容性[J].中国组织工程研究,2012,16(21):3949-3958.
[5]Al Jabbari YS.Physico-mechanical properties and prosthodontic applications of Co-Cr dental alloys:a review of the literature[J].J Adv Prosthodont,2014,6(2):138-145.
[6]Sheibaninia A.Effect of Thermocycling on nickel release from orthodontic arch wires:an in vitro study[J].Biol Trace Elem Res,2014,162(1-3):353-359.
[7]Martíncameán A,Josá,Melladogarcía P,et al.In vitro and in vivo evidence of the cytotoxic and genotoxic effects of metal ions released by orthodontic appliances:A review[J].Environ Toxicol Pharmacol,2015,40(1):86-113.
[8]Mei-Feng HE,Wang H,Jiang H,et al.Effect of hydrogen peroxide concentration on surface properties of Ni-Cr alloys[J].T Nonferr Metal Soc,2016,26(5):1353-1358.
[9]Borg W,Cassar G,Camilleri L,et al.Surface microstructural changes and release of ions from dental metal alloy removable prostheses in patients suffering from acid reflux[J].JProsthodont,2016,27(2).
[10]Bolat G,Paduraru C,Strugaru SCI,et al.Stability of NICRdental alloy after 15 years of service[J].Rev Roum Chim,2014,59(2):91-96.
[11]Habibzadeh S,Rajati HR,Hajmiragha H,et al.Fracture resistances of zirconia,cast Ni-Cr,and fiber-glass composite posts under all-ceramic crowns in endodontically treated premolars[J].J Adv Prosthodont,2017,9(3):170-175.
[12]Paulino SM,Leal MB,Pagnano VO,et al.The castability of pure titanium compared with Ni-Cr and Ni-Cr-Be alloys[J].JProsthet Dent,2007,98(6):445-454.
[13]Yu W,Qian C,Weng W,et al.Effects of lipopolysaccharides on the corrosion behavior of Ni-Cr and Co-Cr alloys[J].J Prosthet Dent,2016,116(2):286-291.
[14]Silva LJD,Leal MB,Valente MLC,et al.Effect of casting atmosphere on the marginal deficiency and misfit of Ni-Cr alloys with and without beryllium[J].J Prosthet Dent,2017,118(1):83-88.
[15]Hong KH,Kim JH,Chang K,et al.The role of Cr on oxide formation in Ni-Cr alloys:A theoretical study[J].Comp Mater Sci,2018,142:185-191.
[16]Ameer MA,Fekry MA,Bahr MA.Effect of Streptococcus mutans on the corrosion behavior of Nano-Coating Ni-Cr Dental Alloy[J].Inter J Electr Sci,2017,12(10):9652-9664.
[17]Mahmood B,Hammert WC.Metal implant allergy[J].J Hand Surg-Am,2015,40(4):831-834.
[18]Palacios MAD,Lopez-Salgueiro R,Sanchez GM,et al.Chronic urticaria after implantation of a mitral annuloplasty ring in a nickel-allergic patient[J].J Invest Allerg Clin,2017,27(1):74-75.
[19]Guerra A,Kirkwood M.Severe generalized dermatitis in a nickel-allergic patient with a popliteal artery nitinol stent[J].JVasc Surg Cases In,2017,3(1):23-25.
[20]Ahlstrom MG,Thyssen JP,Menne T,et al.Prevalence of nickel allergy in Europe following the EU Nickel Directive-a review[J].Contact Dermatitis,2017,77(4):193-200.
[21]Goldenberg A,Vassantachart J,Lin EJ,et al.Nickel allergy in adults in the U.S.:1962 to 2015[J].Derm Cont Atopic Occup Drug,2015,26(5):216.
[22]Zambelli B,Uversky VN,Ciurli S.Nickel impact on human health:An intrinsic disorder perspective[J].BBA-Proteins Proteom,2016,1864(12):1714-1731.
[23]Deo KM,Pages BJ,Ang DL,et al.Transition metal intercalators as anticancer agents-recent advances[J].Int J Mol Sci,2016,17(11):1818.
[24]Issa Y,Brunton P,Waters CM,et al.Cytotoxicity of metal ions to human oligodendroglial cells and human gingival fibroblasts assessed by mitochondrial dehydrogenase activity[J].Dent Mater,2008,24(2):281-287.
[25]Yao Y,Costa M.Toxicogenomic effect of nickel and beyond[J].Arch Toxicol,2014,88(9):1645-1650.
[26]Milheiro A,Nozaki K,Kleverlaan CJ,et al.In vitro cytotoxicity of metallic ions released from dental alloys[J].Odontology,2016,104(2):136-142.
[27]Zambelli B,Ciurli S.Nickel and human health[J].Metal Ions Life Sci,2013,13:321-357.
[28]El-Shafei HM.Assessment of liver function among nickel-plating workers in Egypt[J].East Mediterr Health J,2011,17(6):490-494.
[29]Hackett RL,Sunderma FW.Studies of Nickel carcinogenesis-acute reactions of pulmonary alveolar wall to Nickel carbonyl[J].Am J Pathol,1967,50(6):46.
[30]Kasprzak KS,Sunderman FW,Salnikow K.Nickel carcinogenesis[J].Mutat Res-Rev Mutat,2003,533(1):67-97.
[31]Jones SB,Taylor RL,Colligon JS,et al.Effect of element concentration on nickel release from dental alloys using a novel ion beam method[J].Dent Mater,2010,26(3):249-256.