OTSC在消化道疾病内镜下治疗中的应用进展
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摘要
消化道出血、消化道穿孔及消化道瘘和漏是常见的消化系统疾病,临床上的治疗方式包括保守治疗、内镜下治疗及手术治疗,而随着内镜技术的发展,上述疾病均能在内镜下得到良好的治疗。消化道出血可以通过内镜下局部注射药物、热凝及机械法止血;消化道穿孔及消化道瘘和漏可以通过内镜下缝合、放置支架、纤维蛋白胶封堵及金属夹夹闭等方法治疗。OTSC是一种内镜下使用的新型金属夹,它直径大、咬合力强,可以封闭较大的创面,为内镜治疗提供了更大的空间。
The gastrointestinal bleeding,gastrointestinal perforation,gastrointestinal fistula and leakage are common diseases of digestive system. The therapeutic methods include conservative treatment,endoscopic treatment and surgical treatment,and with the development of endoscopic techniques,these diseases can get good treatment under endoscope. Endoscopic treatment for gastrointestinal bleeding includes clip closure,endoscopic injection of drug and thermocoagulation. Gastrointestinal perforation,fistula and leakage can be treated by endoscopic suturing,stent placement,injection of tissue sealants and clip closure. OTSC( over-the-scope clip) is a new type of metal clip,with a much larger diameter and bite,which can close larger defects,providing more space for endoscopic treatment.
The gastrointestinal bleeding,gastrointestinal perforation,gastrointestinal fistula and leakage are common diseases of digestive system. The therapeutic methods include conservative treatment,endoscopic treatment and surgical treatment,and with the development of endoscopic techniques,these diseases can get good treatment under endoscope. Endoscopic treatment for gastrointestinal bleeding includes clip closure,endoscopic injection of drug and thermocoagulation. Gastrointestinal perforation,fistula and leakage can be treated by endoscopic suturing,stent placement,injection of tissue sealants and clip closure. OTSC( over-the-scope clip) is a new type of metal clip,with a much larger diameter and bite,which can close larger defects,providing more space for endoscopic treatment.
引文
[1]Raju GS,Gajula L.Endoclips for GI endoscopy[J].Gastrointest Endosc,2004,59(2):267-279.
[2]Hachishu T.Evaluation of endoscopic homeostasis using an improved clipping apparatus[J].Surg Endosc,1988,2(1):13-17.
[3]彭学,谢霞,樊超强,等.OTSC金属夹系统在消化道内镜治疗中的应用[J].局解手术学杂志,2017,26(1):26-29.
[4]吴寒,吴毓麟,邹晓平.内镜下止血夹在消化道出血治疗中的应用[J].中华消化内镜杂志,2008,25(8):428-429.
[5]Wedi E,Gonzalez S,Menke D,et al.One hundred and one overthe-scope-clip applications for severe gastrointestinal bleeding,leaks and fistulas[J].World J Gastroenterol,2016,22(5):1844-1853.
[6]史宁,李锟,胡营滨,等.OTSC金属夹治疗难治性急性非静脉曲张性上消化道出血的效果评估[J].中国内镜杂志,2017,4(23):98-101.
[7]林艺志,林炳慧,周剑金,等.Dieulafoy病传统止血夹止血失败后应用蝴蝶夹补救1例[J].临床消化病杂志,2017,29(3):174-175.
[8]Neumann H,Diebel H,Monkemuller K,et al.Description of a new,endoscopic technique to remove the over-the-scope-clip in an ex vivo porcine model(with video)[J].Gastrointest Endosc,2012,76(5):1009-1013.
[9]Caputo A,Schmidt A,Caca K,et al.Efficacy and safety of the rem OVE System for OTSC(R)and FTRD(R)clip removal:Data from a PMCF analysis[J].Minim Invasive Ther Allied Technol,2017,13:1-5.
[10]Manno M,Mangiafico S,Caruso A,et al.First-line endoscopic treatment with OTSC in patients with high-risk non-variceal upper gastrointestinal bleeding:Preliminary experience in 40 cases[J].Surg Endosc,2016,30(5):2026-2029.
[11]Wedi E,Fischer A,Hochberger J,et al.Multicenter evaluation of first-line endoscopic treatment with the OTSC in acute nonvariceal upper gastrointestinal bleeding and comparison with the Rockall cohort:the FLETRock study[J].Surg Endosc,2018,32(1):307-314.
[12]Hans-Jürgen R,Torben G,Christine W,et al.First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding:A single-center experience with 100 cases[J].World J Gastroenterol,2016(41):9162-9171.
[13]Nishiyama N,Mori H,Kobara H,et al.Efficacy and safety of overthe-scope clip:Including complications after endoscopic submucosal dissection[J].World J Gastroenterol,2013,19(18):2752-2760.
[14]Paspatis GA,Dumonceau JM,Barthet M,et al.Diagnosis and management of iatrogenic endoscopic perforations:European Society of Gastrointestinal Endoscopy(ESGE)Position Statement[J].Endoscopy,2014,46(8):693-711.
[15]von Renteln D,Schmidt A,Vassiliou MC,et al.Endoscopic closure of large colonic perforations using an over-the-scope clip:A randomized controlled porcine study[J].Endoscopy,2009,41(6):481-486.
[16]von Renteln D,Schmidt A,Vassiliou MC,et al.Natural orifice transluminal endoscopic surgery gastrotomy closure with an overthe-endoscope clip:A randomized,controlled porcine study(with videos)[J].Gastrointest Endosc,2009,70(4):732-739.
[17]von Renteln D,Rudolph HU,Schmidt A,et al.Endoscopic closure of duodenal perforations by using an over-the-scope clip:A randomized,controlled porcine study[J].Gastrointest Endosc,2010,71(1):131-138.
[18]Banerjee S,Barth BA,Bhat YM,et al.Endoscopic closure devices[J].Gastrointest Endosc,2012,76(2):244-251.
[19]Haito-Chavez Y,Law JK,Kratt T,et al.International multicenter experience with an over-the-scope clipping device for endoscopic management of GI defects(with video)[J].Gastrointest Endosc,2014,80(4):610-622.
[20]牛琼,刘成霞,王伟,等.OTSC金属夹在封闭急性医源性消化道穿孔中的临床应用[J].中国内镜杂志,2017,23(1):84-86.
[21]Honegger C,Valli PV,Wiegand N,et al.Establishment of OverThe-Scope-Clips(OTSC(R))in daily endoscopic routine[J].United European Gastroenterol J,2017,5(2):247-254.
[22]彭学,谢霞,樊超强,等.OTSC金属夹系统在消化道内镜治疗中的应用[J].局解手术学杂志,2017,26(1):26-28.
[23]郭花,王昕,王晓伟,等.OTSC夹闭系统在消化道穿孔关闭技术中的初步应用(含视频)[J].中华消化内镜杂志,2015,32(10):670-672.
[24]Schurr MO,Baur F,Ho CN,et al.Endoluminal full-thickness resection of GI lesions:A new device and technique[J].Minim Invasive Ther Allied Technol,2011,20(3):189-192.
[25]Raithel M,Albrecht H,Scheppach W,et al.Outcome,comorbidity,hospitalization and 30-day mortality after closure of acute perforations and postoperative anastomotic leaks by the over-thescope clip(OTSC)in an unselected cohort of patients[J].Surg Endosc,2017,31(6):2411-2425.
[26]Hagel AF,Naegel A,Lindner AS,et al.Over-the-scope clip application yields a high rate of closure in gastrointestinal perforations and may reduce emergency surgery[J].J Gastrointest Surg,2012,16(11):2132-2138.
[27]Willingham FF,Buscaglia JM.Endoscopic Management of Gastrointestinal Leaks and Fistulae[J].Clin Gastroenterol Hepatol,2015,13(10):1714-1721.
[28]吴秀文,任建安,黎介寿.肠瘘内镜下介入性治疗的研究进展[J].中华外科杂志,2016,54(3):233-237.
[29]Winder JS,Kulaylat AN,Schubart JR,et al.Management of nonacute gastrointestinal defects using the over-the-scope clips(OTSCs):A retrospective single-institution experience[J].Surg Endosc,2016,30(6):2251-2258.
[30]von Renteln D,Denzer UW,Schachschal G,et al.Endoscopic closure of GI fistulae by using an over-the-scope clip(with videos)[J].Gastrointest Endosc,2010,72(6):1289-1296.
[31]Mercky P,Gonzalez JM,Aimore BE,et al.Usefulness of over-thescope clipping system for closing digestive fistulas[J].Dig Endosc,2015,27(1):18-24.
[32]Arezzo A,Verra M,Reddavid R,et al.Efficacy of the over-thescope clip(OTSC)for treatment of colorectal postsurgical leaks and fistulas[J].Surg Endosc,2012,26(11):3330-3333.
[33]Donatelli G,Cereatti F,Dhumane P,et al.Closure of gastrointestinal defects with Ovesco clip:Long-term results and clinical implications[J].Therap Adv Gastroenterol,2016,9(5):713-721.
[34]Disibeyaz S,Koksal A S,Parlak E,et al.Endoscopic closure of gastrointestinal defects with an over-the-scope clip device.A case series and review of the literature[J].Clin Res Hepatol Gastroenterol,2012,36(6):614-621.
[35]Kirschniak A,Subotova N,Zieker D,et al.The Over-The-Scope Clip(OTSC)for the treatment of gastrointestinal bleeding,perforations,and fistulas[J].Surgical Endoscopy,2011,25(9):2901-2905.
[36]王革非,汪志明,吴秀文,等.OTSC吻合夹在消化道瘘治疗中的应用效果[J].中华胃肠外科杂志,2017,20(1):79-83.
[2]Hachishu T.Evaluation of endoscopic homeostasis using an improved clipping apparatus[J].Surg Endosc,1988,2(1):13-17.
[3]彭学,谢霞,樊超强,等.OTSC金属夹系统在消化道内镜治疗中的应用[J].局解手术学杂志,2017,26(1):26-29.
[4]吴寒,吴毓麟,邹晓平.内镜下止血夹在消化道出血治疗中的应用[J].中华消化内镜杂志,2008,25(8):428-429.
[5]Wedi E,Gonzalez S,Menke D,et al.One hundred and one overthe-scope-clip applications for severe gastrointestinal bleeding,leaks and fistulas[J].World J Gastroenterol,2016,22(5):1844-1853.
[6]史宁,李锟,胡营滨,等.OTSC金属夹治疗难治性急性非静脉曲张性上消化道出血的效果评估[J].中国内镜杂志,2017,4(23):98-101.
[7]林艺志,林炳慧,周剑金,等.Dieulafoy病传统止血夹止血失败后应用蝴蝶夹补救1例[J].临床消化病杂志,2017,29(3):174-175.
[8]Neumann H,Diebel H,Monkemuller K,et al.Description of a new,endoscopic technique to remove the over-the-scope-clip in an ex vivo porcine model(with video)[J].Gastrointest Endosc,2012,76(5):1009-1013.
[9]Caputo A,Schmidt A,Caca K,et al.Efficacy and safety of the rem OVE System for OTSC(R)and FTRD(R)clip removal:Data from a PMCF analysis[J].Minim Invasive Ther Allied Technol,2017,13:1-5.
[10]Manno M,Mangiafico S,Caruso A,et al.First-line endoscopic treatment with OTSC in patients with high-risk non-variceal upper gastrointestinal bleeding:Preliminary experience in 40 cases[J].Surg Endosc,2016,30(5):2026-2029.
[11]Wedi E,Fischer A,Hochberger J,et al.Multicenter evaluation of first-line endoscopic treatment with the OTSC in acute nonvariceal upper gastrointestinal bleeding and comparison with the Rockall cohort:the FLETRock study[J].Surg Endosc,2018,32(1):307-314.
[12]Hans-Jürgen R,Torben G,Christine W,et al.First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding:A single-center experience with 100 cases[J].World J Gastroenterol,2016(41):9162-9171.
[13]Nishiyama N,Mori H,Kobara H,et al.Efficacy and safety of overthe-scope clip:Including complications after endoscopic submucosal dissection[J].World J Gastroenterol,2013,19(18):2752-2760.
[14]Paspatis GA,Dumonceau JM,Barthet M,et al.Diagnosis and management of iatrogenic endoscopic perforations:European Society of Gastrointestinal Endoscopy(ESGE)Position Statement[J].Endoscopy,2014,46(8):693-711.
[15]von Renteln D,Schmidt A,Vassiliou MC,et al.Endoscopic closure of large colonic perforations using an over-the-scope clip:A randomized controlled porcine study[J].Endoscopy,2009,41(6):481-486.
[16]von Renteln D,Schmidt A,Vassiliou MC,et al.Natural orifice transluminal endoscopic surgery gastrotomy closure with an overthe-endoscope clip:A randomized,controlled porcine study(with videos)[J].Gastrointest Endosc,2009,70(4):732-739.
[17]von Renteln D,Rudolph HU,Schmidt A,et al.Endoscopic closure of duodenal perforations by using an over-the-scope clip:A randomized,controlled porcine study[J].Gastrointest Endosc,2010,71(1):131-138.
[18]Banerjee S,Barth BA,Bhat YM,et al.Endoscopic closure devices[J].Gastrointest Endosc,2012,76(2):244-251.
[19]Haito-Chavez Y,Law JK,Kratt T,et al.International multicenter experience with an over-the-scope clipping device for endoscopic management of GI defects(with video)[J].Gastrointest Endosc,2014,80(4):610-622.
[20]牛琼,刘成霞,王伟,等.OTSC金属夹在封闭急性医源性消化道穿孔中的临床应用[J].中国内镜杂志,2017,23(1):84-86.
[21]Honegger C,Valli PV,Wiegand N,et al.Establishment of OverThe-Scope-Clips(OTSC(R))in daily endoscopic routine[J].United European Gastroenterol J,2017,5(2):247-254.
[22]彭学,谢霞,樊超强,等.OTSC金属夹系统在消化道内镜治疗中的应用[J].局解手术学杂志,2017,26(1):26-28.
[23]郭花,王昕,王晓伟,等.OTSC夹闭系统在消化道穿孔关闭技术中的初步应用(含视频)[J].中华消化内镜杂志,2015,32(10):670-672.
[24]Schurr MO,Baur F,Ho CN,et al.Endoluminal full-thickness resection of GI lesions:A new device and technique[J].Minim Invasive Ther Allied Technol,2011,20(3):189-192.
[25]Raithel M,Albrecht H,Scheppach W,et al.Outcome,comorbidity,hospitalization and 30-day mortality after closure of acute perforations and postoperative anastomotic leaks by the over-thescope clip(OTSC)in an unselected cohort of patients[J].Surg Endosc,2017,31(6):2411-2425.
[26]Hagel AF,Naegel A,Lindner AS,et al.Over-the-scope clip application yields a high rate of closure in gastrointestinal perforations and may reduce emergency surgery[J].J Gastrointest Surg,2012,16(11):2132-2138.
[27]Willingham FF,Buscaglia JM.Endoscopic Management of Gastrointestinal Leaks and Fistulae[J].Clin Gastroenterol Hepatol,2015,13(10):1714-1721.
[28]吴秀文,任建安,黎介寿.肠瘘内镜下介入性治疗的研究进展[J].中华外科杂志,2016,54(3):233-237.
[29]Winder JS,Kulaylat AN,Schubart JR,et al.Management of nonacute gastrointestinal defects using the over-the-scope clips(OTSCs):A retrospective single-institution experience[J].Surg Endosc,2016,30(6):2251-2258.
[30]von Renteln D,Denzer UW,Schachschal G,et al.Endoscopic closure of GI fistulae by using an over-the-scope clip(with videos)[J].Gastrointest Endosc,2010,72(6):1289-1296.
[31]Mercky P,Gonzalez JM,Aimore BE,et al.Usefulness of over-thescope clipping system for closing digestive fistulas[J].Dig Endosc,2015,27(1):18-24.
[32]Arezzo A,Verra M,Reddavid R,et al.Efficacy of the over-thescope clip(OTSC)for treatment of colorectal postsurgical leaks and fistulas[J].Surg Endosc,2012,26(11):3330-3333.
[33]Donatelli G,Cereatti F,Dhumane P,et al.Closure of gastrointestinal defects with Ovesco clip:Long-term results and clinical implications[J].Therap Adv Gastroenterol,2016,9(5):713-721.
[34]Disibeyaz S,Koksal A S,Parlak E,et al.Endoscopic closure of gastrointestinal defects with an over-the-scope clip device.A case series and review of the literature[J].Clin Res Hepatol Gastroenterol,2012,36(6):614-621.
[35]Kirschniak A,Subotova N,Zieker D,et al.The Over-The-Scope Clip(OTSC)for the treatment of gastrointestinal bleeding,perforations,and fistulas[J].Surgical Endoscopy,2011,25(9):2901-2905.
[36]王革非,汪志明,吴秀文,等.OTSC吻合夹在消化道瘘治疗中的应用效果[J].中华胃肠外科杂志,2017,20(1):79-83.