心理干预配合药物治疗溃疡性结肠炎疗效分析
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摘要
目的探讨心理干预配合药物治疗对溃疡性结肠炎患者治疗效果的影响。方法选择2015-01/2017-12入住四川大学华西第四医院消化内科的溃疡性结肠炎患者186例,采用随机数字表随机分为对照组和干预组两组。对照组采用予以药物治疗;干预组在对照组治疗基础上加上心理干预。分析两组患者治疗疗效与满意度的差异。结果治疗1月后,干预治疗总有效率高于对照组,差异有统计学意义(χ~2=8.997,P<0.05),脓血便、粘液便、腹泻、腹坠胀、腹痛等临床症状的平均改善时间,干预组均短于对照组,差异均有统计学意义(P<0.05);干预组患者的总满意率为90.43%,常规检查组患者的总满意率为68.48%,干预组明显高于对照组,差异有统计学意义(P<0.05)。结论药物治疗联合心理干预治疗溃疡性结肠炎,安全、有效、患者满意度高,有利于改善溃疡性结肠炎患者的生活质量,值得在临床中推广使用。
Objective To explore the effect of psychological intervention combined with medication on Ulcerative Colitis patients. Methods A total of 186 patients with ulcerative colitis treated in West China Fourth Hospital of Sichuan University from January 2015 to December 2017 were randomly divided into the control group and the intervention group. The control group was given drug treatment, and the intervention group was given psychological intervention on the basis of the medication treatment of the control group. The difference of therapeutic efficacy and satisfaction between the two groups was analyzed. Results After 1 month treatment,the total effective rate of intervention was higher than that of control group(χ~2=8.9971,P<0.05). The average improvement time of clinical symptoms, such as abdominal distension, abdominal pain, purulent and bloody stools, mucous stools and diarrhea, in the intervention group was shorter than that in the control group, the difference was statistically significant(P<0.05). The total satisfactory rate of the intervention group was 90.43%, that of the routine examination group was 68.48%,and that of the intervention group was significantly higher than that of the control group(P<0.05). Conclusion Drug therapy combined with psychological intervention in the treatment of ulcerative colitis is safe, effective, and with high satisfaction in patients. This therapy is conducive to improving the living quality of patients with ulcerative colitis,and worthy of clinical application.
Objective To explore the effect of psychological intervention combined with medication on Ulcerative Colitis patients. Methods A total of 186 patients with ulcerative colitis treated in West China Fourth Hospital of Sichuan University from January 2015 to December 2017 were randomly divided into the control group and the intervention group. The control group was given drug treatment, and the intervention group was given psychological intervention on the basis of the medication treatment of the control group. The difference of therapeutic efficacy and satisfaction between the two groups was analyzed. Results After 1 month treatment,the total effective rate of intervention was higher than that of control group(χ~2=8.9971,P<0.05). The average improvement time of clinical symptoms, such as abdominal distension, abdominal pain, purulent and bloody stools, mucous stools and diarrhea, in the intervention group was shorter than that in the control group, the difference was statistically significant(P<0.05). The total satisfactory rate of the intervention group was 90.43%, that of the routine examination group was 68.48%,and that of the intervention group was significantly higher than that of the control group(P<0.05). Conclusion Drug therapy combined with psychological intervention in the treatment of ulcerative colitis is safe, effective, and with high satisfaction in patients. This therapy is conducive to improving the living quality of patients with ulcerative colitis,and worthy of clinical application.
引文
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[20]郭礼平,环雅琴,王莹,等. A型行为对临床心身疾病的影响分析[J].中国健康心理学杂志,2011,19(12):1437-1438.
[2]姚雪洁.小肠克罗恩病的临床特征分析与探讨[D].长沙:中南大学,2013.
[3]于海食,洪缨,王玉蓉.溃疡性结肠炎发病机制[J].实用医学杂志,2010,26(2):323-325.
[4]黄娟,魏艳玲,王军,等.294例炎症性肠病临床特点及随访分析[J].第三军医大学学报,2016,38(8):835-839.
[5]于洋.小肠克罗恩病的临床特征分析[D].长春:吉林大学,2015.
[6]冯桂芳,张晓燕,李娟.90例溃疡性结肠炎患者复发诱因分析及护理[J].现代临床护理,2010(1):51-52.
[7]林海燕,蓝健.溃疡性结肠炎复发相关因素的临床研究[J].中国实用医药,2013(16):130-131.
[8]陆玥琳,沈洪.溃疡性结肠炎复发相关因素研究进展[J].辽宁中医药大学学报,2011(3):28-30.
[9]林赛争,蔡建庭,陈焰,等.难治性炎症性肠病患者艰难梭状芽胞杆菌感染流行病学及临床特征[J].中华医院感染学杂志,2017,27(10):123-126.
[10]秦震声,张燕生,赵耀,等.慢性溃疡性结肠炎复发气象预报研究[J].辽宁中医药大学学报,2013(2):96-97.
[11]张跃,吴耀龙.影响溃疡性结肠炎复发的因素探讨[J].中国医药指南,2013(8):15-16.
[12]孙艳华,许文文,孔凡潇.心理干预联合药物治疗在功能性消化不良患者中的护理体会[J]世界最新医学信息文摘,2017,77(17):247-250.
[13]Kagami S, Rizzo HL, Lee JJ, et al. Circulating Th17, Th22, and The cells are increased in psoriasis[J]. J Invest Dermatol,2010,130(5):1373-1383.
[14]邓琼,周丽华,李汉华,等.门诊系统化管理对溃疡性结肠炎缓解期患者心理状态及生活质量的影响[J].中华护理杂志,2012,47(10):905-907.
[15]Hauser G, Tkalcic M, Stimac D, et al. Gender related differences in quality of life and affective status in patients with inflammatory bowel disease[J].Collegium Antropologicum,2011,35(2):203-207.
[16]夏洛蒂·利波夫,张源中.溃疡性结肠炎的症状与治疗[J].科技信息,2010(28):427-427.
[17]洪玲.溃疡性结肠炎患者的人格特质、心理健康状况和应对方式[J].中国健康心理学杂志,2017,25(9):938-940.
[18]褚晓静,鲁笛,鹿文娟.溃疡性结肠炎患者的压力管理干预[J].贵州医药,2017,41(10):1102-1103.
[19]中华中医药学会脾胃病分会.溃疡性结肠炎中医诊疗共识(2009)[J].中国中西医结合杂志,2010,30(5):527-531.
[20]郭礼平,环雅琴,王莹,等. A型行为对临床心身疾病的影响分析[J].中国健康心理学杂志,2011,19(12):1437-1438.