Pentacam与AS-OCT测量眼前节生物参数的比较
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摘要
目的:在两组人群中比较Pentacam眼前节分析仪与眼前节光相干断层扫描(AS-OCT)测量的角膜曲率及角膜散光、中央角膜厚度和前房深度的差异性、相关性及一致性,为临床使用提供参考。方法:前瞻性临床研究。纳入青年近视术前检查者64例124眼、年龄相关性白内障患者61例85眼,先后使用Pentacam和AS-OCT进行测量,获得眼前节生物参数。在两组人群中采用配对样本t检验分别对两种仪器测量结果的差异性进行比较,所得数据的相关性采用Pearson相关性分析,测量结果的一致性采用Bland-Altman分析。结果:近视组两种仪器测得的陡峭角膜曲率(Ks)、平坦角膜曲率(Kf)、平均角膜曲率(Km)有显著差异(P <0. 001),而白内障组测得的Ks、Kf、Km无差异(P>0. 05),两组人群两种仪器测量的J0(散光参数)、平均角膜厚度(CCT)、前房深度(ACD)均有差异(P<0. 05),测得J45(散光参数)无差异(P>0. 05)。两组人群中两种仪器测量的Ks、Kf、Km、J0、J45、CCT及ACD均具有线性相关(P <0. 001)。近视组测量的Ks、Kf、Km的一致性良好,而白内障组测量的Ks、Kf、Km的一致性较差。结论:Pentacam和AS-OCT测量散光参数、CCT及ACD时具有较好一致性,可互换使用,而测量Ks、Kf、Km时的一致性受年龄相关因素影响,优先考虑选择Pentacam。
AIM: To compare the difference of corneal curvature,astigmatism, central corneal thickness and anterior chamber depth between the Pentacam anterior segment analyzer and anterior segment optical coherence tomography( AS-OCT) in young myopic preoperative and senile cataract patients. METHODS: Prospective clinical study. Totally 64 preoperative examinations( 124 eyes) and 61 senile cataract patients( 85 eyes) were selected. Pentacam and AS-OCT were used to measure the people's parameters of the ophthalmic anterior segment. Paired sample t-test was used to compare the differences of the two devices' measurement results of the two groups. The correlation of the obtained data was analyzed by Pearson correlation analysis. The consistency of the measurement results was analyzed by Bland-Altman plot analysis. RESULTS: There were significant differences in measuring steep Keratometry( Ks),flat Keratometry( Kf)and mean Keratometry( Km) between the two devices of myopia( P < 0. 001), but there was no statistically significant difference in the cataract group( P>0.05). The astigmatic parameters J0, central corneal thickness( CCT),and anterior chamber depth( ACD) measured by the devices and there were statistically significant differences between the two devices( P<0.05) while there was no significant difference in the measured astigmatic parameters J45( P>0.05). The results of Ks,Kf,Km,J0,J45,CCT and ACD measured by the two devices in both groups were linearly related( P<0.001). The Bland-Altman plot analyses showed that the two devices had comparable results for J0, J45, CCT and ACD. The consistency of Ks,Kf and Km measured by the myopia group was good,while the consistency of Ks,Kf and Km measured by the cataract group was poor.CONCLUSION: Pentacam and AS-OCT measurements of the ophthalmic anterior segment are consistent with astigmatic parameters,CCT and ACD,and can be used interchangeably. The consistency of Ks,Kf and Km is affected by age related factors, and Pentacam is preferred.
AIM: To compare the difference of corneal curvature,astigmatism, central corneal thickness and anterior chamber depth between the Pentacam anterior segment analyzer and anterior segment optical coherence tomography( AS-OCT) in young myopic preoperative and senile cataract patients. METHODS: Prospective clinical study. Totally 64 preoperative examinations( 124 eyes) and 61 senile cataract patients( 85 eyes) were selected. Pentacam and AS-OCT were used to measure the people's parameters of the ophthalmic anterior segment. Paired sample t-test was used to compare the differences of the two devices' measurement results of the two groups. The correlation of the obtained data was analyzed by Pearson correlation analysis. The consistency of the measurement results was analyzed by Bland-Altman plot analysis. RESULTS: There were significant differences in measuring steep Keratometry( Ks),flat Keratometry( Kf)and mean Keratometry( Km) between the two devices of myopia( P < 0. 001), but there was no statistically significant difference in the cataract group( P>0.05). The astigmatic parameters J0, central corneal thickness( CCT),and anterior chamber depth( ACD) measured by the devices and there were statistically significant differences between the two devices( P<0.05) while there was no significant difference in the measured astigmatic parameters J45( P>0.05). The results of Ks,Kf,Km,J0,J45,CCT and ACD measured by the two devices in both groups were linearly related( P<0.001). The Bland-Altman plot analyses showed that the two devices had comparable results for J0, J45, CCT and ACD. The consistency of Ks,Kf and Km measured by the myopia group was good,while the consistency of Ks,Kf and Km measured by the cataract group was poor.CONCLUSION: Pentacam and AS-OCT measurements of the ophthalmic anterior segment are consistent with astigmatic parameters,CCT and ACD,and can be used interchangeably. The consistency of Ks,Kf and Km is affected by age related factors, and Pentacam is preferred.
引文
1 Thibos LN,Wheeler W,Horner D. Power vectors:an application of Fourier analysis to the description and statistical analysis of refractive error. Optom Vis Sci 1997;74(6):367-375
2 Mehdizadeh M.Effect of axial length and keratometry measurement error on intraocular lens implant power prediction formulas in pediatric patients. J AAPOS 2008; 12(2):173-176
3 Savini G,Carbonelli M,Sbreglia A, et al. Comparison of anterior segment measurements by 3 Scheimpflug tomographers and 1 Placido corneal topographer. J Cataract Refract Surg 2011;37(9):1679-1685
4 Bedard M, Martin NJ, Krueger P,et al.Assessing reproducibility of data obtained with instruments based on continuous measurements. Exp Aging Res 2000;26(4):353-365
5 Bland JM,Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 327(8476):307-310
6 Srivannaboon S,Soeharnila,Chirapapaisan C,et al. Comparison of corneal astigmatism and axis location in cataract patients measured by total corneal power, automated keratometry, and simulated keratometry. J Cataract Refract Surg 2012; 38(12):2088-2093
7 Karunaratne N. Comparison of the Pentacam equivalent keratometry reading and IOL Master keratometry measurement in intraocular lens power calculations. Clin Exp Ophthalmol 2013;41(9):825-834
8 Tai LY,Khaw KW,Ng CM,et al. Central corneal thickness measurements with different imaging devices and ultrasound pachymetry.Cornea 2013;32(6):766-771
9 Emerah S,Elzakzouk E,Farag M. Comparison of Central Corneal Thickness Measurements by Pentacam and Ultrasound Pachymetry in Normal Myopic Patients. Electron Physician 2016;8(12):3441-3444
10刘圆媛,路承喆,汤欣.前节OCT在观察后发性白内障方面的应用价值.中国实用眼科杂志2017;35(3):247-251
11 Ishibazawa A, Igarashi S, Hanada K, et al. Central corneal thickness measurements with Fourier-domain optical coherence tomography versus ultrasonic pachymetry and rotating Scheimpflug camera. Cornea 2011; 30(6):615-619
12 Jr MRL, Kaupp S, Schallhorn S, et al. Orbscan pachymetry:Implications of a repeated measures and diurnal variation analysis.Ophthalmology 1999; 106(5):977-981
13 Khoramnia R,Rabsilber TM,Auffarth GU. Central and peripheralpachymetry measurements according to age using the Pentacam rotating Scheimpflug camera.J Cataract Refract Surg 2007;33(5):830-836
14 Shankar H,Taranath D,Santhirathelagan CT,et al. Anterior segment biometry with the Pentacam:comprehensive assessment of repeatability of automated measurements. J Cataract Refract Surg 2008; 34(1):103
15金红颖,姚克,杨亚波,等.三种仪器对近视患者眼前节生物学参数测量的比较.中华实验眼科杂志2014;32(12):1097-1101
16 Olsen T. Prediction of the effective postoperative(intraocular lens)anterior chamber depth. J Cataract Refract Surg 2006; 32(3):419-424
17 Awwad ST,Manasseh C, Bowman RW, et al. Intraocular lens power calculation after myopic laser in situ keratomileusis:Estimating the corneal refractive power. J Cataract Refract Surg 2008; 34(7):1070-1076
18 O'Donnell C,Hartwig A,Radhakrishnan H. Comparison of central corneal thickness and anterior chamber depth measured using LenStar LS900, Pentacam,and Visante AS-OCT. Cornea 2012;31(9):983-988
19 Dinc UA, Gorgun E, Oncel B,et al. Assessment of anterior chamber depth using Visante optical coherence tomography,slitlamp optical coherence tomography,IOL Master,Pentacam and Orbscan IIz.Ophthalmologica 2010;224(6):341-346
20 Elbaz U, Barkana Y, Gerber Y, et al. Comparison of different techniques of anterior chamber depth and keratometric measurements. Am J Ophthalmol 2007; 143(1):48-53
2 Mehdizadeh M.Effect of axial length and keratometry measurement error on intraocular lens implant power prediction formulas in pediatric patients. J AAPOS 2008; 12(2):173-176
3 Savini G,Carbonelli M,Sbreglia A, et al. Comparison of anterior segment measurements by 3 Scheimpflug tomographers and 1 Placido corneal topographer. J Cataract Refract Surg 2011;37(9):1679-1685
4 Bedard M, Martin NJ, Krueger P,et al.Assessing reproducibility of data obtained with instruments based on continuous measurements. Exp Aging Res 2000;26(4):353-365
5 Bland JM,Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 327(8476):307-310
6 Srivannaboon S,Soeharnila,Chirapapaisan C,et al. Comparison of corneal astigmatism and axis location in cataract patients measured by total corneal power, automated keratometry, and simulated keratometry. J Cataract Refract Surg 2012; 38(12):2088-2093
7 Karunaratne N. Comparison of the Pentacam equivalent keratometry reading and IOL Master keratometry measurement in intraocular lens power calculations. Clin Exp Ophthalmol 2013;41(9):825-834
8 Tai LY,Khaw KW,Ng CM,et al. Central corneal thickness measurements with different imaging devices and ultrasound pachymetry.Cornea 2013;32(6):766-771
9 Emerah S,Elzakzouk E,Farag M. Comparison of Central Corneal Thickness Measurements by Pentacam and Ultrasound Pachymetry in Normal Myopic Patients. Electron Physician 2016;8(12):3441-3444
10刘圆媛,路承喆,汤欣.前节OCT在观察后发性白内障方面的应用价值.中国实用眼科杂志2017;35(3):247-251
11 Ishibazawa A, Igarashi S, Hanada K, et al. Central corneal thickness measurements with Fourier-domain optical coherence tomography versus ultrasonic pachymetry and rotating Scheimpflug camera. Cornea 2011; 30(6):615-619
12 Jr MRL, Kaupp S, Schallhorn S, et al. Orbscan pachymetry:Implications of a repeated measures and diurnal variation analysis.Ophthalmology 1999; 106(5):977-981
13 Khoramnia R,Rabsilber TM,Auffarth GU. Central and peripheralpachymetry measurements according to age using the Pentacam rotating Scheimpflug camera.J Cataract Refract Surg 2007;33(5):830-836
14 Shankar H,Taranath D,Santhirathelagan CT,et al. Anterior segment biometry with the Pentacam:comprehensive assessment of repeatability of automated measurements. J Cataract Refract Surg 2008; 34(1):103
15金红颖,姚克,杨亚波,等.三种仪器对近视患者眼前节生物学参数测量的比较.中华实验眼科杂志2014;32(12):1097-1101
16 Olsen T. Prediction of the effective postoperative(intraocular lens)anterior chamber depth. J Cataract Refract Surg 2006; 32(3):419-424
17 Awwad ST,Manasseh C, Bowman RW, et al. Intraocular lens power calculation after myopic laser in situ keratomileusis:Estimating the corneal refractive power. J Cataract Refract Surg 2008; 34(7):1070-1076
18 O'Donnell C,Hartwig A,Radhakrishnan H. Comparison of central corneal thickness and anterior chamber depth measured using LenStar LS900, Pentacam,and Visante AS-OCT. Cornea 2012;31(9):983-988
19 Dinc UA, Gorgun E, Oncel B,et al. Assessment of anterior chamber depth using Visante optical coherence tomography,slitlamp optical coherence tomography,IOL Master,Pentacam and Orbscan IIz.Ophthalmologica 2010;224(6):341-346
20 Elbaz U, Barkana Y, Gerber Y, et al. Comparison of different techniques of anterior chamber depth and keratometric measurements. Am J Ophthalmol 2007; 143(1):48-53