经皮骨水泥注入对老年骨质疏松性椎体压缩性骨折患者的治疗效果分析
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摘要
目的对老年骨质疏松性椎体压缩性骨折患者采用经皮骨水泥注入方法治疗的效果进行探讨。方法选取我院2016年3月～2018年3月收治的94例老年骨质疏松性椎体压缩性骨折患者进行研究,随机分为观察组与对照组,各47例,对照组采用传统钉棒系统内固定术治疗,观察组采用经皮骨水泥注入术治疗,对两组患者治疗效果进行对比。结果在术中出血量、手术时间、创面大小、镇痛药物使用剂量及骨水泥渗漏与不足率等指标对比中,观察组均明显低于对照组,差异有统计学意义(P <0.05);与术前比较,两组患者椎体高度、Cobb角术后均明显改善,差异有统计学意义(P <0.05);且术后48h、6个月,观察组椎体高度、Cobb角改善明显优于对照组,差异有统计学意义(P <0.05)。结论对老年骨质疏松性压缩性骨折患者采用经皮骨水泥注入术治疗,具有内固定支撑牢固、测量精确、操作简单的优势,且术中止血效果好,远期固定支撑效果理想,疗效确切,在临床中值得推广应用。
Objective To investigate therapeutic effect of percutaneous bone cement injection in the treatment of osteoporotic vertebral compression fractures in the elderly. Methods 94 senile patients with osteoporosis vertebral compression fracture in our hospital from March 2016 to March 2018 were randomly divided into observation group and control group,with 47 cases in each group.The control group was treated with traditional nail rod system internal fixation,while the observation group was treated by percutaneous cement injection.The effect was compared. Results Intraoperative blood volume,operation time,wound size,pain medication use dosage and bone cement leakage rate were significantly lower than that of control group,and that difference was statistically significant(P < 0.05).Compared with the preoperative comparison,the vertebral height and Cobb Angle of the two groups were significantly improved after surgery,and the difference was statistically significant(P < 0.05).48 h and 6 months after surgery,the improvement of vertebral height and Cobb Angle in the observation group were significantly better than that in the control group,and the differences were statistically significant(P < 0.05). Conclusion For the elderly patients with osteoporosis compressive fracture,percutaneous bone cement injection has the advantages of firm internal fixation support,accurate measurement and simple operation,good intraoperative hemostasis effect,ideal long-term fixation support effect and exact curative effect,which is worthy of promotion and application in clinical practice.
Objective To investigate therapeutic effect of percutaneous bone cement injection in the treatment of osteoporotic vertebral compression fractures in the elderly. Methods 94 senile patients with osteoporosis vertebral compression fracture in our hospital from March 2016 to March 2018 were randomly divided into observation group and control group,with 47 cases in each group.The control group was treated with traditional nail rod system internal fixation,while the observation group was treated by percutaneous cement injection.The effect was compared. Results Intraoperative blood volume,operation time,wound size,pain medication use dosage and bone cement leakage rate were significantly lower than that of control group,and that difference was statistically significant(P < 0.05).Compared with the preoperative comparison,the vertebral height and Cobb Angle of the two groups were significantly improved after surgery,and the difference was statistically significant(P < 0.05).48 h and 6 months after surgery,the improvement of vertebral height and Cobb Angle in the observation group were significantly better than that in the control group,and the differences were statistically significant(P < 0.05). Conclusion For the elderly patients with osteoporosis compressive fracture,percutaneous bone cement injection has the advantages of firm internal fixation support,accurate measurement and simple operation,good intraoperative hemostasis effect,ideal long-term fixation support effect and exact curative effect,which is worthy of promotion and application in clinical practice.
引文
[1]易剑华,陈升浩,蔡平原,等.高粘稠度骨水泥PVP术和PKP术治疗老年椎体压缩性骨折的临床效果对比[J].生物骨科材料与临床研究,2017,14(5):13-17.
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[9]张胜林,徐信龙,殷建华,等.椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折疗效分析[J].海南医学院学报,2013,19(12):1733-1736.
[10]叶宏,陈小杰.球囊扩张椎体后凸成形注入骨水泥治疗老年骨质疏松性椎体压缩性骨折[J].中国医药导报,2011,8(33):49-51.
[11]杨中华,崔青,魏华,等.经皮椎体成形术磷酸钙骨水泥治疗老年骨质疏松性椎体压缩性骨折[J].中国骨质疏松杂志,2010,16(6):439-441.
[12]景元海,杨小玉,赵丛然,等.经皮椎体注入骨水泥治疗老年脊椎骨质疏松压缩性骨折[J].中国组织工程研究与临床康复,2007,11(32):6484-6486.
[13]冯万立,康健,卫建民,等.高黏度骨水泥单侧与双侧经皮椎体成形术治疗骨质疏松性椎体压缩性骨折的临床疗效对比研究[J].中国医学前沿杂志(电子版),2017,9(6):47-50.
[14]颜学亮,曹奇,陈小明.小剂量骨水泥经皮椎体成形术治疗老年性骨质疏松症多节段跳跃性脊柱压缩性骨折的疗效分析[J].中南医学科学杂志,2016,44(4):368-370.
[15]王传功,崔文峰,尹双成,等.经皮椎体成形术治疗骨质疏松性椎体压缩性骨折骨水泥渗漏的预防[J].中国医药导刊,2015,17(9):906-907.
[2]徐本惠.经皮椎体成形骨水泥注入治疗老年脊椎骨质疏松压缩性骨折的临床分析[J].中国卫生标准管理,2017,8(15):40-41.
[3]周瑞明,管义红,王全兵,等.不同黏度骨水泥联合经皮椎体后凸成形术治疗骨质疏松椎体压缩性骨折的疗效[J].武警后勤学院学报(医学版),2017,26(6):509-511.
[4]毋崇岭,陈文华,王新虎.经皮椎体后凸成形术在治疗老年骨质疏松性椎体压缩性骨折中骨水泥注射量与疗效的相关性研究[J].山西医药杂志,2017,46(4):371-374.
[5]杨勇杰.经皮椎体注入骨水泥治疗老年脊椎骨质疏松压缩性骨折临床观察[J].深圳中西医结合杂志,2015,25(23):98-100.
[6]王成日,廖海浪,杨文彬,等.经皮椎体成形术结合分次灌注骨水泥技术治疗老年重度椎体压缩性骨折32例[J].广西医科大学学报,2015,32(3):462-463.
[7]欧长福.经皮椎体后凸成形术中应用不同剂量骨水泥对骨质疏松性压缩性骨折疗效的影响[J].中外医学研究,2017,15(31):37-38.
[8]李坚,陈其昕,张金喜,等.经皮椎体成形骨水泥注入治疗老年脊椎骨质疏松压缩性骨折的疗效[J].中国老年学杂志,2014,34(15):4376-4378.
[9]张胜林,徐信龙,殷建华,等.椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折疗效分析[J].海南医学院学报,2013,19(12):1733-1736.
[10]叶宏,陈小杰.球囊扩张椎体后凸成形注入骨水泥治疗老年骨质疏松性椎体压缩性骨折[J].中国医药导报,2011,8(33):49-51.
[11]杨中华,崔青,魏华,等.经皮椎体成形术磷酸钙骨水泥治疗老年骨质疏松性椎体压缩性骨折[J].中国骨质疏松杂志,2010,16(6):439-441.
[12]景元海,杨小玉,赵丛然,等.经皮椎体注入骨水泥治疗老年脊椎骨质疏松压缩性骨折[J].中国组织工程研究与临床康复,2007,11(32):6484-6486.
[13]冯万立,康健,卫建民,等.高黏度骨水泥单侧与双侧经皮椎体成形术治疗骨质疏松性椎体压缩性骨折的临床疗效对比研究[J].中国医学前沿杂志(电子版),2017,9(6):47-50.
[14]颜学亮,曹奇,陈小明.小剂量骨水泥经皮椎体成形术治疗老年性骨质疏松症多节段跳跃性脊柱压缩性骨折的疗效分析[J].中南医学科学杂志,2016,44(4):368-370.
[15]王传功,崔文峰,尹双成,等.经皮椎体成形术治疗骨质疏松性椎体压缩性骨折骨水泥渗漏的预防[J].中国医药导刊,2015,17(9):906-907.