摘要
<正>胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor,PSTT)是指源于中间型滋养细胞(intermediate trophoblasts,Its),来自胎盘种植部位的一种特殊类型的滋养细胞肿瘤(gestational trophoblastic disease,GTD),其病理形态及生物学行为与其他滋养细胞肿瘤有诸多不同。胎盘部位滋养细胞肿瘤(PSTT)临床较少见,患者多因闭经、流产、葡萄胎或足月妊娠后阴道不规则流血而就诊。Kurman等~([1])于1976年首次使用"胎盘部位假瘤"描述该病,认为该病是滋养细胞侵蚀特性的
引文
[1]Kurman RJ,Scully RE,Norris HJ.Trophoblastic pseudotumor of the uterus.Anexaggerated form of“Syncytial endometritis”simulating a malignant tumor[J].Cancer,1976,38(3):1214-1226.
[2]Scully RE,Young RH.Trophoblastic pseudotumor:a reappraisal[J].Am J Sury Pathol,1981,5(1):75-76.
[3]Schmid P,Nagai Y,Agarwal R,et al.Prognostic markersand long-term outcome of placental-site trophoblastictumours:a retrospective observational study[J].Lancet,2009,374:48-55.
[4]Luiza IW,Taylor SE,Gao FF,et al.Placental site trophoblastic tumor:immunohistochemistry algorihm key to diagnosis and review of literature[J].Gynecol Oncol Case Rep,2013,7:13-15.
[5]Pongsarantakul S,Kietpeerakool C.Hysterectomy in gestational tropoblastic neoplasia:Chiang Mai University Hospital’s experience[J].Asian Pac J Cancer Prev,2009,10(2):311-314.
[6]Zhao J,Xiang Y.The diagnosis and treatment of placental site trophoblastic tumor[J].Journal of Practical Oncology,2008,23(1):5-7.[赵俊,向阳.胎盘部位滋养细胞肿瘤及其诊治[J].实用肿瘤杂志,2008,23(1):5-7.]
[7]Hyman Dm,Bakios L,Gualtiere G,et al.Placental site trophoblastic tumor:analysis of presentation,treatment,and outcome[J].Gynecol Oncol,2013,129(1):58-62.
[8]Vantrommel NE,Lok CA,Bulten H,et al.Long-term outcome of placental site trophoblastic tumor in The Netherlands[J].Reprod Med,2013,58(5-6):224-228.
[9]Kong HY,Wan XY.The progress in diagnosis and treatment of placental site trophoblastic tumor[J].Progress in Obstetrics and Gynecology,2010,19:227-230.[孔虹燕,万小云.胎盘部位滋养细胞肿瘤的诊治进展[J].现代妇产科进展,2010,19:227-230.]
[10]Wang Y,Sun L,Liu AJ.Clinicopathological features of metastatic placental site trophoblastic tumor[J].Chinese Journal of Diagnostic Pathology,2012,27(3):363-367.[王昀,孙璐,刘爱军.转移性胎盘部位滋养细胞肿瘤临床病理观察[J].诊断病理学杂志,2012,27(3):363-367.]
[11]Shen XY,Ren T,Feng FZ,et al.The value of serum chorionic gonadotropin in the diagnosis and treatment of placental site trophoblastic tumors[J].Chinese Journal of Clinical Obstetrics and Gynecology,2012,13(3):198.[沈晓燕,任彤,冯凤芝,等.人绒毛膜促性腺激素在胎盘部位滋养细胞肿瘤诊治中的价值[J].中国妇产科临床杂志,2012,13(3):198.]
[12]Okumura M,Fushida K,Rezende WW,et al.Sonographic appearance ofgestational trophoblastic disease evolving into epithelioid trophoblastic tumor[J].Ultrasound Obstet Gynecol,2010,36(2):249-251.
[13]Moutte A,Doret M,Hajri T,et al.Placental site and epithelioid trophoblastic tumours:diagnostic pitfalls[J].Gynecol Oncol,2013,128(3):568-572.
[14]Saso S,Haddad I,Ellis P,et al.Placental site trophoblastic tumours and the concept pf fertility preservation[J].BIOG,2012,119:369-374.
[15]Shen X,Xiong Y,Guo L,et al.Fertility-preserving treatment in young patients with placental site trophpblastic tumors[J].Int J Gynecol Cancer,2012,22:869-874.
[16]Zhang JY,Li L,Chen WJ,et al.Clinical pathologic observation of placental site trophoblastic tumor[J].Chinese Journal of Clinical and Experimental Pathology,2014,30(7):725-727.[张江宇,李荔,陈文静,等.胎盘部位滋养细胞肿瘤临床病理观察[J].临床与实验病理学杂志,2014,30(7):725-727.]
[17]Zhao J,Xiang Y,Guo LN,et al.Reservation of fertility for seventeen patients with placental site trophoblastic tumor[J].Chinese Journal of Obstetrics and Gynecology,2014,49(4):265-269.[赵俊,向阳,郭丽娜,等.胎盘部位滋养细胞肿瘤保留生育功能治疗17例临床分析[J].中华妇产科杂志,2014,49(4):265-269.]
[18]Zheng Y,Bao L,Ning Y,et al.Retrospective analysis of the clinicopathologic and prognostic characteristics of stageⅠplacental site trophoblastic tumor in China[J].Int J Gynaecol Obstet,2015,129:67-70.
[19]Schmid P,Nagai Y,Agarwal R,et al.Prognostic markers and long-term outcome of placental-site trophoblastic tumours:a retrospective observational study[J].Lancet,2009,374:48-55.
[20]Hyman DM,Bakios L,Gualtiere G,et al.Placental site trophoblastic tumor:analysis of presentation,treatment,and outcome[J].Gynecol Oncol,2013,129:58-62.
[21]Seckl MJ,Sebire NJ,Berkowitz RS.Gestational trophoblastic disease[J].Lancet,2010,376:717-729.
[22]Lurain JR.Gestational trophoblastic diseaseⅡ:classification and management of gestational trophoblastic neoplasia[J].Am J Obstet Gynecol,2011,204(1):11-18.