虎符铜砭刮痧治疗糖尿病周围神经病变疗效观察
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摘要
目的探讨虎符铜砭刮痧治疗糖尿病周围神经病变的临床疗效。方法选择2017年10月至2018年3月期间惠州市中医医院内分泌科收治的82例糖尿病周围神经病变患者为研究对象,根据随机数表法分为观察组和对照组,每组41例,对照组患者予甲钴胺治疗,观察组患者在此基础上应用虎符铜砭刮痧,疗程均为28 d。比较两组患者的临床疗效,治疗前后胫总及腓总神经的运动神经传导速度(MNCV)、感觉神经传导速度(SNCV)以及症状总评分法(TSS)评分的变化。结果观察组患者的治疗总有效率为85.37%,明显高于对照组的68.29%,差异有统计学意义(P<0.05);治疗后,观察组患者的TSS总分为(5.13±1.81)分,明显低于对照组的(7.68±1.26)分,差异有统计学意义(P<0.05);观察组患者的胫总神经、腓总神经的MNCV分别为(33.91±1.52) m/s、(33.69±1.41) m/s,SNCV分别为(33.97±1.44) m/s、(34.26±1.67) m/s,明显快于对照组的(31.98±1.61) m/s、(31.91±1.22) m/s、(32.02±1.38) m/s、(32.12±1.53) m/s,差异均有统计学意义(P<0.05)。结论虎符铜砭刮痧治疗糖尿病周围神经病变可以明显改善神经传导速度及患者的临床症状,提高临床疗效。
Objective To investigate the clinical effect of Hufu Copper Gua Sha(scraping therapy) on diabetic peripheral neuropathy. Methods Eighty-two patients with diabetic peripheral neuropathy who were treated in Department of Endocrinology, Huizhou Traditional Chinese Medicine Hospital from October 2017 to March 2018 were selected as the subjects. They were divided into observation group and control group according to the random number table method, with 41 patients in each group. The control group was treated with mecobalamin, and the observation group was treated with Hufu copper Gua Sha. The treatment lasted for 28 days. The clinical efficacy, motor nerve conduction velocity(MNCV), sensory nerve conduction velocity(SNCV), and total symptom score(TSS) of tibial and peroneal nerves were compared before and after treatment. Results The total effective rate of patients in observation group was 85.37%, significantly higher than 68.29% of control group(P<0.05). After treatment, the total score of TSS in observation group was 5.13±1.81, significantly lower than 7.68±1.26 in control group(P<0.05). The MNCV of common tibial nerve and common peroneal nerve in observation group was(33.91 ± 1.52) m/s,(33.69 ± 1.41) m/s, and SNCV were(33.97 ± 1.44) m/s,(34.26 ± 1.67) m/s, significantly faster than(31.98 ± 1.61) m/s,(31.91 ± 1.22) m/s;(32.02 ± 1.38) m/s,(32.12 ± 1.53) m/s in the control group(P<0.05). Conclusion Hufu copper Gua Sha can significantly improve nerve conduction velocity and clinical symptoms of diabetic peripheral neuropathy, and improve clinical efficacy.
Objective To investigate the clinical effect of Hufu Copper Gua Sha(scraping therapy) on diabetic peripheral neuropathy. Methods Eighty-two patients with diabetic peripheral neuropathy who were treated in Department of Endocrinology, Huizhou Traditional Chinese Medicine Hospital from October 2017 to March 2018 were selected as the subjects. They were divided into observation group and control group according to the random number table method, with 41 patients in each group. The control group was treated with mecobalamin, and the observation group was treated with Hufu copper Gua Sha. The treatment lasted for 28 days. The clinical efficacy, motor nerve conduction velocity(MNCV), sensory nerve conduction velocity(SNCV), and total symptom score(TSS) of tibial and peroneal nerves were compared before and after treatment. Results The total effective rate of patients in observation group was 85.37%, significantly higher than 68.29% of control group(P<0.05). After treatment, the total score of TSS in observation group was 5.13±1.81, significantly lower than 7.68±1.26 in control group(P<0.05). The MNCV of common tibial nerve and common peroneal nerve in observation group was(33.91 ± 1.52) m/s,(33.69 ± 1.41) m/s, and SNCV were(33.97 ± 1.44) m/s,(34.26 ± 1.67) m/s, significantly faster than(31.98 ± 1.61) m/s,(31.91 ± 1.22) m/s;(32.02 ± 1.38) m/s,(32.12 ± 1.53) m/s in the control group(P<0.05). Conclusion Hufu copper Gua Sha can significantly improve nerve conduction velocity and clinical symptoms of diabetic peripheral neuropathy, and improve clinical efficacy.
引文
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[4]肖丽梅,孟宪璞,韩明林,等.分段刮痧与针刺治疗颈型颈椎病疗效对照观察[J].中国针灸, 2014, 34(8):751-754.
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[6] ZIEGLER D, AMETOV A, BARINOV A, et al. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy:the SYDNEY 2 trial[J]. Diabetes Care, 2006, 29(11):2365-2370.
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[9]彭晓智,裴翔,胥政.甲钴胺治疗糖尿病周围神经病变的疗效及其对患者血浆同型半胱氨酸水平的影响[J].海南医学, 2016, 27(10):1597-1599.
[10]魏薇,王中京,周玲,等. 2型糖尿病周围神经病变的危险因素分析[J].海南医学, 2017, 28(20):3379-3381.
[11]施君,张文川.糖尿病周围神经病变发病机制的研究进展[J].上海交通大学学报(医学版), 2012, 32(1):116-119.
[12]时霄冰,于生元,杨爱民,等.神经传导速度对糖尿病痛性周围神经病的诊断价值[J].现代生物医学进展, 2013, 13(6):1108-1110.
[13]常亮.甲钴胺治疗糖尿病周围神经病变的临床观察[J].海峡药学,2016, 28(3):124-126.
[14]罗春英,吴建能,杨靖.α-硫辛酸联合甲钴胺对老年痛性糖尿病周围神经病变氧化应激的影响[J].中国老年学杂志, 2016, 36(10):2398-2399.
[15]李树斌.中医为主治疗糖尿病并发周围神经炎50例临床分析[J].光明中医, 2014, 29(2):309-310.
[16]陈国凯,宝珠,任婷婷.老年糖尿病周围血管病中医证候规律及与糖脂代谢的关系研究[J].河北中医药学报, 2016, 31(3):19-22.
[17]姜荣荣,徐桂华,陈华,等.从文献计量学角度探刮痧治疗的优势病种[J].中医学报, 2014, 29(5):756-758.
[18]陈华,徐桂华,姜荣荣,等.刮痧对腰椎间盘突出症大鼠血清IgG及椎间盘组织病理改变的影响[J].南京中医药大学学报, 2014, 30(5):450-453.
[19]刘海华,王莹莹,吴远,等.刮痧治疗原发性高血压34例临床观察[J].世界针灸杂志(英文版), 2014, 24(4):54-58.
[2]文海杰.糖尿病周围神经病变的临床分析[J].中国实用医刊, 2016,43(8):122-123.
[3]王国凤,徐宁,尹冬,等.依帕司他、甲钴胺及α-硫辛酸不同组合治疗糖尿病周围神经病变的疗效观察[J].中国糖尿病杂志, 2013, 21(9):779-781.
[4]肖丽梅,孟宪璞,韩明林,等.分段刮痧与针刺治疗颈型颈椎病疗效对照观察[J].中国针灸, 2014, 34(8):751-754.
[5]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2010年版)[J].中国实用乡村医生杂志, 2012, 19(4):1-15.
[6] ZIEGLER D, AMETOV A, BARINOV A, et al. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy:the SYDNEY 2 trial[J]. Diabetes Care, 2006, 29(11):2365-2370.
[7]邹立华,李惠,陈小丹,等.甲钴胺联合α-硫辛酸、血府逐瘀胶囊治疗糖尿病周围神经病变疗效观察[J].中西医结合心脑血管病杂志,2014, 12(3):269-270.
[8]黄晓敏,李枢,刘伟芳.住院2型糖尿病患者糖尿病周围神经病变相关因素分析[J].新医学, 2014, 45(8):515-518.
[9]彭晓智,裴翔,胥政.甲钴胺治疗糖尿病周围神经病变的疗效及其对患者血浆同型半胱氨酸水平的影响[J].海南医学, 2016, 27(10):1597-1599.
[10]魏薇,王中京,周玲,等. 2型糖尿病周围神经病变的危险因素分析[J].海南医学, 2017, 28(20):3379-3381.
[11]施君,张文川.糖尿病周围神经病变发病机制的研究进展[J].上海交通大学学报(医学版), 2012, 32(1):116-119.
[12]时霄冰,于生元,杨爱民,等.神经传导速度对糖尿病痛性周围神经病的诊断价值[J].现代生物医学进展, 2013, 13(6):1108-1110.
[13]常亮.甲钴胺治疗糖尿病周围神经病变的临床观察[J].海峡药学,2016, 28(3):124-126.
[14]罗春英,吴建能,杨靖.α-硫辛酸联合甲钴胺对老年痛性糖尿病周围神经病变氧化应激的影响[J].中国老年学杂志, 2016, 36(10):2398-2399.
[15]李树斌.中医为主治疗糖尿病并发周围神经炎50例临床分析[J].光明中医, 2014, 29(2):309-310.
[16]陈国凯,宝珠,任婷婷.老年糖尿病周围血管病中医证候规律及与糖脂代谢的关系研究[J].河北中医药学报, 2016, 31(3):19-22.
[17]姜荣荣,徐桂华,陈华,等.从文献计量学角度探刮痧治疗的优势病种[J].中医学报, 2014, 29(5):756-758.
[18]陈华,徐桂华,姜荣荣,等.刮痧对腰椎间盘突出症大鼠血清IgG及椎间盘组织病理改变的影响[J].南京中医药大学学报, 2014, 30(5):450-453.
[19]刘海华,王莹莹,吴远,等.刮痧治疗原发性高血压34例临床观察[J].世界针灸杂志(英文版), 2014, 24(4):54-58.