依诺肝素在新辅助化疗后结直肠癌患者围手术期静脉血栓栓塞症预防的疗效评估
摘要
<正>静脉血栓栓塞症(venous thromboembolism,VTE)主要包括深静脉血栓形成(deep vein thrombosis,DVT)和肺血栓栓塞病(pulmonary thromboembolism,PTE),是癌症患者常见并发症之一。Trinh等~([1])研究发现VTE是癌症患者术后死亡原因之一,其死亡率约为非VTE患者的5倍。癌症患者
引文
[1]Trinh Vincent Q,Karakiewicz Pierre I,et al. Venous thromboembolism after major cancer surgery:temporal trends and patterns of care[J]. JAMA Surg,2014,149(1):43-49.
[2]Heidrich H,Konau E,Hesse P. Asymptomatic venous thrombrosis in cancer patients-a problem often overlooked. Results of a retrospective and prospective study[J]. VASA,2009,38(2):160-166
[3]Nagata C,Tanabe H,Takakura S,et al. Randomized controlled trial of enoxaparin versus intermittent pneumatic compression for venous thromboembolism prevention in Japanese surgical patients with gynecologic malignancy[J]. J Obstet Gynaecol Res,2015,41(9):1440-1448.
[4]Diaz AH,Rodgers GM,Gilreath JA. Enoxaparin once daily vs.twice daily dosing for the treatment of venous thromboembolism in cancer patients:a literature summary[J]. J Oncol Pharm Pract,2011,18(2):264-270.
[5]Geerts WH,Bergqvist D,Pineo GF,et al. Prevention of venousthromboembolism:American college of chest physicians evidence-based clinical practice guidelines(8 th Editio)[J].Chest,2008,133(6 Suppl):381S-453S.
[6]Sakon M,Kobayashi T,Shimazui T. Efficacy and safety of enoxaparin in Japanese patients undergoing curative abdominal or pelvic cancer surgery:results from a multicenter, randomized, open-label study[J]. Thromb Res,2010,125(3):e65-70.
[7]Leizorovicz A. Epidemiology of post-operative venous thromboembolism in Asian patients. Results of the SMART venography study[J]. Haematologica,2007,92(9):1194-1200.
[8]Malinoski D,Jafari F,Ewing T,et al. Standard prophylactic enoxaparin dosing leads to inadequate anti-xa levels and increased deep venous thrombosis rates in critically ill trauma and surgical patients[J]. J Trauma,2010,68(4):874-80.
[2]Heidrich H,Konau E,Hesse P. Asymptomatic venous thrombrosis in cancer patients-a problem often overlooked. Results of a retrospective and prospective study[J]. VASA,2009,38(2):160-166
[3]Nagata C,Tanabe H,Takakura S,et al. Randomized controlled trial of enoxaparin versus intermittent pneumatic compression for venous thromboembolism prevention in Japanese surgical patients with gynecologic malignancy[J]. J Obstet Gynaecol Res,2015,41(9):1440-1448.
[4]Diaz AH,Rodgers GM,Gilreath JA. Enoxaparin once daily vs.twice daily dosing for the treatment of venous thromboembolism in cancer patients:a literature summary[J]. J Oncol Pharm Pract,2011,18(2):264-270.
[5]Geerts WH,Bergqvist D,Pineo GF,et al. Prevention of venousthromboembolism:American college of chest physicians evidence-based clinical practice guidelines(8 th Editio)[J].Chest,2008,133(6 Suppl):381S-453S.
[6]Sakon M,Kobayashi T,Shimazui T. Efficacy and safety of enoxaparin in Japanese patients undergoing curative abdominal or pelvic cancer surgery:results from a multicenter, randomized, open-label study[J]. Thromb Res,2010,125(3):e65-70.
[7]Leizorovicz A. Epidemiology of post-operative venous thromboembolism in Asian patients. Results of the SMART venography study[J]. Haematologica,2007,92(9):1194-1200.
[8]Malinoski D,Jafari F,Ewing T,et al. Standard prophylactic enoxaparin dosing leads to inadequate anti-xa levels and increased deep venous thrombosis rates in critically ill trauma and surgical patients[J]. J Trauma,2010,68(4):874-80.