穴位贴敷法治疗小儿咳嗽变异性哮喘的临床疗效及机制分析
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摘要
目的:观察西医联合穴位贴敷治疗小儿咳嗽变异性哮喘的临床疗效及机制分析。方法:选择我院2014年12月-2017年12月收治的咳嗽变异性哮喘患儿共60例,将60例患儿随机分为对照组和观察组各30例,两组患儿采用常规治疗方法,如化痰平喘、止咳等药物,详细药物:氨溴特罗口服溶液治疗,10 mL/次,2次/d;富马酸酮替芬片治疗,1片/次,2次/d。观察组在此基础上加用穴位贴敷治疗,以健肤按摩膏分别对患儿的肺俞、天突、足三里穴位按摩后进行贴敷,经医用纱布固定,两组共治疗3个疗程。观察两组的临床疗效、临床症状评分和细胞免疫功能。结果:对照组治疗的总有效率为73.33%,观察组治疗的总有效率为96.67%,观察组的治疗总有效率高于对照组(P <0.05)。两组患者临床症状评分和细胞免疫功能在治疗前对比差异无统计学意义(P> 0.05),在治疗后两组患者的评分较治疗前出现下降(P <0.05),且治疗后观察组的评分改善程度较对照组明显(P <0.05),对比差异具有统计学意义。结论:西医联合穴位贴敷治疗小儿咳嗽变异性哮喘的临床疗效较高,能有效改善患者的临床症状,其机制可能与患儿外周血T淋巴细胞亚群紊乱得到改善相关。
Objective: To observe clinical effects and mechanism of western medicine plus acupoint application on children coughvariant asthma. Methods: 60 children with cough-variant asthma were randomly divided into the observation group and the control group, 30 cases in each. Conventional treatment methods were chosen in two groups. The observation group was treated by acupoint application more. Feishu( 肺俞), Tiantu( 天突) and Zusanli( 足三里) was massaged and treated by acupoint application with Jianfu Anmo Gao( 健肤按摩膏). Results: The total effective rate was 96.67% in the observation group, higher than 73.33% in the control group. Before the treatment, the comparisons of symptoms score and immune function in both groups appeared no significant difference; but after the treatment, the symptoms score was decreased(P<0.05), and the improvement of symptoms score was better than the control group, with a significant difference. Conclusion: Western medicine plus acupoint application was effective on variant asthma in children with effectively improved symptoms, and the mechanism may be related to the improvement of PB T-lymphocyte disorders in children patients.
Objective: To observe clinical effects and mechanism of western medicine plus acupoint application on children coughvariant asthma. Methods: 60 children with cough-variant asthma were randomly divided into the observation group and the control group, 30 cases in each. Conventional treatment methods were chosen in two groups. The observation group was treated by acupoint application more. Feishu( 肺俞), Tiantu( 天突) and Zusanli( 足三里) was massaged and treated by acupoint application with Jianfu Anmo Gao( 健肤按摩膏). Results: The total effective rate was 96.67% in the observation group, higher than 73.33% in the control group. Before the treatment, the comparisons of symptoms score and immune function in both groups appeared no significant difference; but after the treatment, the symptoms score was decreased(P<0.05), and the improvement of symptoms score was better than the control group, with a significant difference. Conclusion: Western medicine plus acupoint application was effective on variant asthma in children with effectively improved symptoms, and the mechanism may be related to the improvement of PB T-lymphocyte disorders in children patients.
引文
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[4]李云龙,杨良俊,许锦奋,等.药物敷贴配合穴位注射治疗小儿咳嗽变异性哮喘76例临床观察[J].北方药学,2015,12(9):59-60.
[5]中华医学会儿科学分会呼吸组,《中华儿科杂志》编辑会委员.儿童支气管哮喘诊断与防治指南[J].中华儿科杂志,2008,46(10):745-753.
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[7]殷旭,刘贵云.刘贵云教授应用沙参麦冬汤的经验[J].中医临床研究,2016,8(13):74-75.
[8]李巧香,刘贵云,詹红艳,等.益肺平喘汤联合穴位贴敷治疗小儿咳嗽变异性哮喘的临床观察[J].中国中医急症,2017,26(5):860-863.
[2]赵红霞,冯海军.益气补肾汤联合沙美特罗替卡松治疗咳嗽变异性哮喘的临床观察[J].中国医药导刊,2015,17(3):282-283.
[3]甘苑入.益气补肾汤联合沙美特罗替卡松治疗咳嗽变异性哮喘的临床观察[J/CD].中西医结合心血管病电子杂志,2017,5(25):156-157.
[4]李云龙,杨良俊,许锦奋,等.药物敷贴配合穴位注射治疗小儿咳嗽变异性哮喘76例临床观察[J].北方药学,2015,12(9):59-60.
[5]中华医学会儿科学分会呼吸组,《中华儿科杂志》编辑会委员.儿童支气管哮喘诊断与防治指南[J].中华儿科杂志,2008,46(10):745-753.
[6]陈玉琴.中药内服联合中药穴位贴敷治疗小儿咳嗽变异性哮喘72例[J].中国农村卫生,2015,8(14):84.
[7]殷旭,刘贵云.刘贵云教授应用沙参麦冬汤的经验[J].中医临床研究,2016,8(13):74-75.
[8]李巧香,刘贵云,詹红艳,等.益肺平喘汤联合穴位贴敷治疗小儿咳嗽变异性哮喘的临床观察[J].中国中医急症,2017,26(5):860-863.